Metapathway biotransformation (Equus caballus)
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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Cytochrome P450 Flavin monooxygenases Aldo-keto reductases Sulfotransferases Glucuronosyltransferases N-acetyltransferases Epoxide hydrolases Glutathione transferases Methyltransferases Nucleophiles Glutathione conjugation Sulfation Acetylation Glucuronidation Reduction Hydrolysis Oxidation Methylation Glutathione peroxidases Glutathione reductase Glutathione synthetase Amino acid conjugation Electrophiles Amino acid acyl transferases Xenobiotic substrate Substrate-Ac Substrate-Gl Substrate-SG Substrate-SO3H Aldo-keto reductase Sulfotransferase N-acetyltransferase Glucuronosyltransferase CYP450 Glutathione transferase Flavin monooxygenase Methyltransferase Substrate-CH3 XP_001494003.2 XP_001499231.2 Substrate-Aa Amino acid acyltransferase XP_001492270.2 XP_001492219.1 XP_001496001.1 XP_001496254.1 XP_001496075.2 UGT1A1 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT1A10 UGT2A1 UGT2A2 UGT2A3 UGT2B4 UGT2B7 UGT2B11 UGT2B15 UGT2B17 UGT2B28 Substrate-OH Substrate-SH Substrate-NH2 COMT NNMT XP_001490376.2 XP_001500553.1 TPMT_HORSE A8WCD7_HORSE XP_001493936.1 XP_001499815.2 CYP2A6 CYP2C8 CYP2C9 CYP2C19 A8WDL7_HORSE CYP3A4 CYP3A5 CYP2D6 CP11A_HORSE CYP11B2 CYP2A13 XP_001918061.1 CYP11B1 CYP2C18 CYP2A7 XP_001498220.1 XP_001497396.2 CYP2S1 XP_001503107.2 CYP2B6 CYP2W1 CYP3A7 CYP3A43 CYP4B1 CYP4F2 CYP4F3 CYP4F8 CYP4F11 CYP4F12 XP_001914769.1 XP_001490382.2 XP_001493525.2 CYP4Z1 CYP46A1 XP_001496962.1 XP_001915852.1 XP_001501478.2 CP17A_HORSE CP19A_HORSE XP_001918021.1 CYP21A2 XP_001488979.2 XP_001502548.1 XP_001488867.2 CYP26C1 XP_001492328.1 Q2LE11_HORSE XP_001488205.2 XP_001498224.1 XP_001491520.1 XP_001489035.1 XP_001492725.1 XP_001916131.1 GPX2 Q9N2C4_HORSE GPX4 Q4TUB6_HORSE GSTA1 GSTM1 XP_001489453.1 GSTA5 GSTA2 XP_001503655.1 GSTA3 XP_001503157.1 XP_001489979.1 GSTM2 XP_001495454.2 XP_001918060.1 GSTM5 XP_001499427.2 XP_001499416.2 GSTP1 GSTT2 GSTT2B XP_001493411.1 XP_001501941.1 MGST2 XP_001493558.1 XP_001487907.1 XP_001487907.1 NAT6 XP_001489957.2 NAT8 XP_001492728.1 NAT10 XP_001488543.2 XP_001489266.1 XP_001491545.2 XP_001501166.1 XP_001498955.2 XP_001502088.1 XP_001502088.1 XP_001502088.1 XP_001502088.1 SULT1B1 XP_001501402.2 XP_001493215.1 XP_001493338.1 SULT1C4 SULT1E1 SULT2A1 SULT2B1 XP_001487968.2 XP_001499929.2 CHST1 CHST2 XP_001503816.1 XP_001498064.1 XP_001498871.1 XP_001498871.1 CHST7 XP_001489097.1 CHST9 XP_001489868.1 XP_001498449.2 XP_001492298.2 CHST13 CHST14 XP_001494941.2 XP_001497881.2 XP_001495217.1 XP_001505104.1 XP_001494608.1 XP_001501008.1 XP_001500863.2 HS3ST3A1 HS3ST3B1 HS3ST4 XP_001504142.1 XP_001915244.1 XP_001915539.1 HS6ST2 XP_001916527.1 XP_001503761.1 XP_001503966.1 XP_001503334.1 XP_001503353.1 XP_001495936.1 AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR7A2 XP_001917301.1 XP_001497124.1 XP_001500782.1 XP_001490613.2 AKR1B10 KCNAB2 XP_001504849.2 Substrate=O Substrate-O-R XP_001504071.1 XP_001504745.1 GLYATL1 GLYATL2 Name: Metapathway biotransformation Last Modified: 2/20/2013 Organism: Equus caballus
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