Biogenic amine synthesis (Drosophila melanogaster)

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1AcetylserotoninSerotoninGABA5-Hydroxy-L-tryptophanAcetylcholineTyrosineHistidineDopamineHistamineMelatoninGlutamateSynthesis pathways for biogenic amines (in blue)follow solid arrows through enzymatic steps,while degradation steps follow dashed arrows.PhenylalanineL-DopaTryptophanCholineEpinephrineNorepinephrineDdcHdcAANATTrhHnpleTbhDdcPNMTGAD2Gad1MAOAACHEMAOADdcCOMTChaASMT


Description

Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source: http://www.whatislife.com/reader2/Metabolism/pathway/Neurotransmitter.html

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Quality Tags

Ontology Terms

 

Bibliography

  1. Purves, Dale, Augustine, George J., Fitzpatrick, David, Katz, Lawrence C., LaMantia, Anthony-Samuel, McNamara, James O., Williams, S. Mark.; ''Neuroscience''; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=neurosci&part=A405, 2001

History

View all...
CompareRevisionActionTimeUserComment
120778view22:11, 4 January 2022Khanspersadded missing xref
120777view22:07, 4 January 2022Khanspersconnected enzymes, added xrefs for metabolites
116914view11:56, 15 May 2021EweitzModified title
102068view00:25, 28 November 2018Elisson nlGene id added
92244view23:39, 15 May 2017MaintBotReverted to version '10:43, 16 September 2016' by MaintBot
92243view22:15, 15 May 2017KrasinQuick edit to datanode annotation or property
89510view10:43, 16 September 2016Mkutmonontology tag fix
89467view13:38, 15 September 2016Mkutmonremove space from ontology term id
77402view22:36, 5 September 2014MaintBotremoved homology mapp label
71543view19:25, 17 October 2013MaintBotAutomated update of data sources
70074view09:13, 12 July 2013Mkutmonfixed unconnected lines
67084view10:04, 26 June 2013Christine ChichesterOntology Term : 'biogenic amine biosynthetic pathway' added !
62150view10:43, 25 April 2013EgonwConverted labels into Metabolite DataNode's.
62147view10:41, 25 April 2013EgonwThe applet changed the coordinate space, so when I copied in the unconverted metabolite locations... :( Undo revision 62146 by [[Special:Contributions/Egonw|Egonw]] ([[User talk:Egonw|Talk]])
62146view10:34, 25 April 2013EgonwConverted labels into Metabolite DataNode's.
62145view10:33, 25 April 2013EgonwConnected dots
40892view22:34, 1 March 2011MaintBotRemoved redundant pathway information and comments
35163view14:41, 11 February 2010ThomasModified description
35162view14:41, 11 February 2010Thomasadded literature
34158view21:08, 9 December 2009MaintBotAutomatic update of empty xrefs
20945view11:30, 14 November 2008MaintBot[[Pathway:Drosophila melanogaster:Biogenic Amine Synthesis]] moved to [[Pathway:WP125]]: Moved to stable identifier
8588view14:04, 7 January 2008MaintBotAdded to category $category
8586view14:04, 7 January 2008AlexanderPicoUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
5-Hydroxy-L-tryptophanMetaboliteHMDB00472 (HMDB)
AANATGeneProductENSG00000129673 (Ensembl)
ACHEGeneProductENSG00000087085 (Ensembl)
ASMTGeneProductENSG00000196433 (Ensembl)
AcetylcholineMetaboliteHMDB00895 (HMDB)
AcetylserotoninMetaboliteHMDB01238 (HMDB)
COMTGeneProduct47091 (Entrez Gene)
ChaGeneProduct42249 (Entrez Gene)
CholineMetaboliteHMDB00097 (HMDB)
DdcGeneProduct35190 (Entrez Gene)
DopamineMetaboliteHMDB00073 (HMDB)
EpinephrineMetaboliteHMDB00068 (HMDB)
GABAMetaboliteCHEBI:16865 (ChEBI)
GAD2GeneProductENSG00000136750 (Ensembl)
Gad1GeneProduct38484 (Entrez Gene)
GlutamateMetaboliteCHEBI:14321 (ChEBI)
HdcGeneProduct36076 (Entrez Gene)
HistamineMetaboliteHMDB00870 (HMDB)
HistidineMetaboliteHMDB00177 (HMDB)
HnGeneProduct38871 (Entrez Gene)
L-DopaMetaboliteHMDB00181 (HMDB)
MAOAGeneProductENSG00000189221 (Ensembl)
MelatoninMetaboliteHMDB01389 (HMDB)
NorepinephrineMetaboliteHMDB00216 (HMDB)
PNMTGeneProductENSG00000141744 (Ensembl)
PhenylalanineMetaboliteCHEBI:17295 (ChEBI)
SerotoninMetaboliteHMDB00259 (HMDB)
TbhGeneProduct31718 (Entrez Gene)
TrhGeneProduct38121 (Entrez Gene)
TryptophanMetaboliteHMDB00929 (HMDB)
TyrosineMetaboliteCHEBI:17895 (ChEBI)
pleGeneProduct38746 (Entrez Gene)

Annotated Interactions

No annotated interactions

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