Oxidative stress response (Danio rerio)

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Induction ofantioxidant genesAdaptive responseRepressionRepression of ROS-producing systemsInhibition of oxidasesTF activationTF inhibitionStress-regulated MAP kinaseActivationImmediate-earlygene inductionReactive Oxygen SpeciesLOC555669TXNRD1GSTT1bcatcybaTXNRD2mapk14atxn2MT1Xsi:dkey-117m1.6cyp1aGPX1aNFKB1mapk10hmox1xdhsp1Nrf2sod2nqo1sod1UGT1A6MGST1zgc:110010gclcfosMAOAGPX3JUNBGPX1bGSTT1a


Description

No description

Comments

GenMAPP notes 
Adapted from Biochem J 1999 Sep 15;342 Pt 3:481-96 Morel Y, Barouki R. Repression of gene expression by oxidative stress. Biochem J 1999 Sep 15;342 Pt 3:481-96
GenMAPP remarks 
Adapted from rat by GenMAPP.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP408(r21540) with a 58% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
116901view11:31, 15 May 2021EweitzModified title
91955view13:58, 6 April 2017LWackersUpdated annotations. Split GSTT2 into its zebrafish orthologues.
88284view14:42, 1 August 2016FehrhartOntology Term : 'oxidative stress response pathway' added !
71514view19:22, 17 October 2013MaintBotAutomated update of data sources
68644view04:58, 6 July 2013MaintBotUpdated to 2013 gpml schema
40812view22:17, 1 March 2011MaintBotRemoved redundant pathway information and comments
34200view21:28, 9 December 2009MaintBotAutomatic update of empty xrefs
32338view13:32, 15 August 2009MaintBotFixed text labels
31951view13:01, 14 August 2009MaintBotFixed group labels
31382view20:41, 13 August 2009MaintBotFixed text labels
31084view01:34, 30 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
GPX1aGeneProductENSDARG00000018146 (Ensembl)
GPX1bGeneProductNM_001004634 (RefSeq)
GPX3GeneProduct798788 (Entrez Gene)
GSTT1aGeneProductENSDARG00000042428 (Ensembl)
GSTT1bGeneProductENSDARG00000017388 (Ensembl)
JUNBGeneProduct407086 (Entrez Gene)
LOC555669GeneProduct555669 (Entrez Gene)
MAOAGeneProductENSDARG00000023712 (Ensembl)
MGST1GeneProduct449784 (Entrez Gene)
MT1XGeneProduct
NFKB1GeneProduct565756 (Entrez Gene)
Nrf2GeneProduct
TXNRD1GeneProduct352924 (Entrez Gene)
TXNRD2GeneProductENSDARG00000075923 (Ensembl)
UGT1A6GeneProduct
catGeneProduct30068 (Entrez Gene)
cybaGeneProduct393551 (Entrez Gene) Probe set ID: u18729
cyp1aGeneProduct140634 (Entrez Gene)
fosGeneProduct394198 (Entrez Gene)
gclcGeneProduct326857 (Entrez Gene)
hmox1GeneProduct791518 (Entrez Gene)
mapk10GeneProduct569698 (Entrez Gene)
mapk14aGeneProduct65237 (Entrez Gene)
nqo1GeneProduct322506 (Entrez Gene)
si:dkey-117m1.6GeneProduct794006 (Entrez Gene)
sod1GeneProduct30553 (Entrez Gene)
sod2GeneProduct335799 (Entrez Gene)
sp1GeneProduct324109 (Entrez Gene)
txn2GeneProduct402938 (Entrez Gene)
xdhGeneProduct560486 (Entrez Gene)
zgc:110010GeneProduct553575 (Entrez Gene)

Annotated Interactions

No annotated interactions
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