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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Thromboxane Platelet activating factor Thyrotropin Endothelin Neuromedin U Hormone protein Interleukin-8 Thrombin Prostacyclin Lutropin-choriogonadotropic hormone APJ like Follicle stimulating hormone C-X-C Chemokine Cxcr3 Blr1 Cx3cr1 Cxcr4 Vasopressin-like Avpr1a Avpr1b Avpr2 Oxt Oxtr Avp Alpha Adrenoceptors Adrenoceptors Adra2a Adra2b Adra2c Adra1d Adra1a Adra1b Neuropeptide Y Npy6r Gpr83 Npy5r Ppyr1 Npy1r Npy2r Olfactory Olfr708 Olfr870 Olfr713 Olfr70 Olfr707 Olfr71 Olfr715 Olfr716 Olfr1355 Q9EPV1 Olfr155 Olfr710 Gabbr1 Olfr15 Q9EPG0 Olfr159 Olfr714 Olfr19 Olfr17 Olfr157 Olfr156 Adenosine Nucleotide-like Adora2a Adora3 Adora2b Chemokine receptor-like Cmklr1 Gpr30 Gpr33 Gpr44 Bombesin Brs3 Nmbr Grpr Bradykinin Bdkrb2 Bdkrb1 GPR37 / endothelin B-like Gpr37 Gpr37l1 Prostanoid Prostaglandin Ptger4 Ptger1 Ptgdr Ptgfr Ptger2 Ptger3 Neurotensin Ntsr2 Ntsr1 Proteinase activated F2rl2 F2rl3 F2rl1 Rhodopsin Other Opn4 Opn3 Rgr Rrh Opioid Oprl1 Oprm1 Oprd1 Oprk1 CCK Cckar Cckbr Class A Orphan/other Gpr45 P2ry13 Gpr27 Gpr3 Mas1 Gpr63 Gpr19 Tcp10c Gpr34 Gpr87 Gpr12 P2ry14 Gpr65 Cysltr1 Gpr109b P2ry12 Cmkor1 Purinoceptors Gpr35 P2ry6 P2ry2 Ltb4r1 P2ry1 Sucnr1 P2ry4 Beta Adrenoceptors Adrb1 Adrb3 Adrb2 Fmet-leu-phe Fpr-rs4 Fprl1 Fpr-rs1 Fpr1 Fpr-rs3 Fpr-rs2 Angiotensin Peptide Agtr1b Agtr2 Agtr1 Melanocortin Mc2r Mc1r Mc5r Mc4r Mc3r Olfactory type 3 Olfr888 Olfr959 Olfr968 Olfr970 Olfr957 Olfr948 Olfr876 Olfr749 Olfr933 Olfr703 Olfr705 Olfr971 Olfr893 Olfr889 Olfr16 Olfr704 Q9EQ94 Olfr144 Olfr945 Olfr160 Olfr148 Olfr944 Olfr955 Olfr145 Olfr961 Olfr894 Olfr938 Olfr874 Olfr926 Olfr954 Olfr934 Olfr242 Olfr151 Olfr972 Olfr701 Olfr711 Olfr878 Olfr930 Olfr27 Olfr887 Olfr49 Olfr143 Olfr480 Olfr943 Olfr44 Olfr146 Olfr2 Olfr6 Olfr960 Olfr937 Olfr706 Thyrotropin-releasing hormone & Secretagogue Trhr2 Trhr Galanin Galr1 Galr3 Galr2 Acetylcholine (muscarinic) Amine Chrm4 Chrm1 Chrm2 Chrm3 C-C Chemokine Chemokine Ccr2 Ccr1 Ccr9 Ccr3 Ccr1l1 Ccr4 Ccr8 Ccrl2 Ccbp2 Ccr5 Ccr6 Cannabis Cnr1 Cnr2 Somatostatin Sstr2 Sstr5 Sstr3 Sstr1 Sstr4 Rhodopsin Vertebrate (Rhod)opsin Rho Opn1sw Opn1mw C5a anaphylatoxin C3ar1 C5r1 Agtrl1 Fshr Dopamine Tbxa2r Histamine Ednrb Ptafr Il8rb Lhcgr F2r Melatonin Ptgir Nmur1 Serotonin Tshr Drd4 Drd3 Htr1a Hrh1 Htr1b Hrh2 Htr1f Htr1d Htr4 Htr5b Htr5a Htr6 Htr7 Htr2b Htr2c Htr2a Gpr50 Mtnr1a Group object Name: GPCRs, class A rhodopsin-like Organism: Mus musculus
Description
This pathway was created using the GPCRDB (Horn et al., 1998),
http://www.gpcr.org/7tm/ (originally at
http://www.cmbi.kun.nl/7tm/ ). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
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Ontology Terms
Bibliography
Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, Edvardsen O, Campagne F, Vriend G; ''GPCRDB: an information system for G protein-coupled receptors.''; Nucleic Acids Res, 1998 PubMed Europe PMC Scholia Karchin R, Karplus K, Haussler D; ''Classifying G-protein coupled receptors with support vector machines.''; Bioinformatics, 2002 PubMed Europe PMC Scholia History
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No annotated interactions
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