Salvage pathways of pyrimidine deoxyribonucleotides (Saccharomyces cerevisiae)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none uracilthymidineCDD1phosphatethymineDeoxyuridinephosphatePyrimidine ribonucleotide salvage pathwayH2OH+2'-deoxycytidineNH3dUMP2-deoxy-α-D-ribose 1-phosphatedTMPATPADPH+ATPADPH+CytosineH2O2'-deoxyribosecCMPATPADPH+de novo biosynthesis of pyrimidine deoxyribonucleotidesde novo biosynthesis of pyrimidine deoxyribonucleotidesde novo biosynthesis of pyrimidine deoxyribonucleotidesURH1URK12.4.2.22.4.2.32.7.1.212.7.1.1452.4.2.22.4.2.4Name: Salvage pathways of pyrimidine deoxyribonucleotidesOrganism: Saccharomyces cerevisiae


Description

The deoxynucleotides required for DNA synthesis can either be made de novo, or they can be salvaged from endogenous degradation processes. If the required substrates are available, the salvage pathways of pyrimidine deoxyribonucleotides are preferred over de novo synthesis pathways for pyrimidine biosynthesis. As with many of the metabolic pathways of S. cerevisiae, the pathways for the salvage of pyrimidine deoxyribonucleotides are regulated by a variety of processes, including transcription regulation. Description adapted from YeastPathways (https://pathway.yeastgenome.org/)

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Quality Tags

Image:Curated.pngApproved version

Ontology Terms

Pathway Ontology : DNA replication pathway
 

Bibliography

  1. ''salvage pathways of pyrimidine deoxyribonucleotides''; YeastPathways,

History

View all...
CompareRevisionActionTimeUserComment
135919
Approved
view18:53, 27 November 2024KhanspersModified title
135918view18:51, 27 November 2024KhanspersModified description
135917view18:50, 27 November 2024KhanspersOntology Term : 'PW:0000005' removed !
135916view18:50, 27 November 2024KhanspersOntology Term : 'nucleotide metabolic pathway' added !
135915view18:49, 27 November 2024KhanspersOntology Term : 'classic metabolic pathway' added !
135914view18:49, 27 November 2024Khanspersremoved GenMAPP comments, updated reference
135913view18:48, 27 November 2024Khanspersupdating
135912view18:20, 27 November 2024Khanspersupdating
117334view11:50, 20 May 2021EweitzModified title
87642view08:54, 25 July 2016LindarieswijkOntology Term : 'carbohydrate metabolic pathway' added !
69826view14:45, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
69607view20:32, 8 July 2013MaintBotUpdated to 2013 gpml schema
41839view04:50, 2 March 2011MaintBotRemoved redundant pathway information and comments
21141view11:30, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Ribose and Deoxyribose Phosphate Metabolism]] moved to [[Pathway:WP220]]: Moved to stable identifier
12834view08:04, 17 May 2008MaintBotautomated metabolite conversion
8906view14:12, 7 January 2008MaintBotAdded to category $category
8904view14:11, 7 January 2008M.BraymerUploaded new pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
2'-deoxycytidineMetabolite15698 (ChEBI)
2'-deoxyriboseMetabolite131350 (ChEBI)
2-deoxy-α-D-ribose 1-phosphateMetabolite57259 (ChEBI)
2.4.2.2GeneProduct2.4.2.2 (Enzyme Nomenclature)
2.4.2.3GeneProduct2.4.2.3 (Enzyme Nomenclature)
2.4.2.4GeneProduct2.4.2.4 (Enzyme Nomenclature)
2.7.1.145GeneProduct2.7.1.145 (Enzyme Nomenclature)
2.7.1.21GeneProduct2.7.1.21 (Enzyme Nomenclature)
ADPMetabolite58-64-0 (CAS)
ATPMetabolite1927-31-7 (CAS)
CDD1GeneProductS000004235 (SGD)
CytosineMetabolite16040 (ChEBI)
DeoxyuridineMetabolite951-78-0 (CAS)
H+Metabolite15378 (ChEBI)
H2OMetabolite15377 (ChEBI)
NH3Metabolite28938 (ChEBI)
Pyrimidine ribonucleotide salvage pathwayPathwayWP95 (WikiPathways)
URH1GeneProductS000002808 (SGD)
URK1GeneProductS000005295 (SGD)
cCMPMetabolite57566 (ChEBI)
dTMPMetabolite63528 (ChEBI)
dUMPMetabolite246422 (ChEBI)
de novo biosynthesis of pyrimidine deoxyribonucleotidesPathwayWP36 (WikiPathways)
phosphateMetabolite14265-44-2 (CAS)
thymidineMetabolite50-89-5 (CAS)
thymineMetabolite65-71-4 (CAS)
uracilMetabolite66-22-8 (CAS)

Annotated Interactions

No annotated interactions

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