miRNA biogenesis (Homo sapiens)
From WikiPathways
Description
microRNA biogenesis + an example of a miRBase entry.
As an example immature hsa-mir-146a is shown
Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2338).Quality Tags
Ontology Terms
Bibliography
- Yang JS, Phillips MD, Betel D, Mu P, Ventura A, Siepel AC, Chen KC, Lai EC; ''Widespread regulatory activity of vertebrate microRNA* species.''; RNA, 2011 PubMed Europe PMC Scholia
- Wienholds E, Plasterk RH; ''MicroRNA function in animal development.''; FEBS Lett, 2005 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name ![]() | Type ![]() | Database reference ![]() | Comment ![]() |
---|---|---|---|
DGCR8 | GeneProduct | ENSG00000128191 (Ensembl) ![]() | |
DICER1 | GeneProduct | ENSG00000100697 (Ensembl) ![]() | |
DROSHA | GeneProduct | ENSG00000113360 (Ensembl) ![]() | |
GTP | Metabolite | HMDB0001440 (HMDB) ![]() | |
RAN | GeneProduct | 5901 (Entrez Gene) ![]() | |
TRBP | Protein | Q15633 (Uniprot-TrEMBL) ![]() | |
XPO5 | GeneProduct | ENSG00000124571 (Ensembl) ![]() |
Annotated Interactions
No annotated interactions