Secretion of hydrochloric acid in parietal cells (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Stomach lumenVenous bloodCarbonate dehydrase activityZincGastrinAcetylcholineATP4AHistamineCarbon dioxideWaterBicarbonate ionHydrogenChloride ionPotassiumHRH2CHRM1CCKBRBicarbonate ionHydrogenChloride ionPotassiumChloride ionName: Secretion of hydrochloric acid in parietal cellsOrganism: Homo sapiens


Description

Gastric parietal cells are stomach epithelial cells. They secrete gastric acid and intrinsic factor. This pathway is primarily based on https://en.wikipedia.org/wiki/Parietal_cell

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Quality Tags

Image:Curated.pngApproved version

Ontology Terms

 

Bibliography

  1. Murakami H, Sly WS; ''Purification and characterization of human salivary carbonic anhydrase.''; J Biol Chem, 1987 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
129119
Approved
view22:07, 11 March 2024EweitzStandardize font
129118view22:06, 11 March 2024EweitzCenter metabolite
129117view22:05, 11 March 2024EweitzEconomize layout, standardize case
129111view21:35, 11 March 2024EweitzOntology Term : 'epithelial cell of stomach' added !
129110view21:34, 11 March 2024EweitzOntology Term : 'epithelial cell' added !
117821view14:56, 22 May 2021EweitzModified title
106721view13:16, 17 September 2019MaintBotHMDB identifier normalization
87647view08:54, 25 July 2016LindarieswijkOntology Term : 'acid-base homeostasis pathway' added !
78485view10:28, 7 January 2015MaintBotadded missing graphIds
77607view08:03, 30 September 2014Mkutmonconnected lines
76321view07:23, 2 July 2014Mkutmonchanged carbonate dehydratase activity from gene product to label.
73972view10:11, 13 March 2014MaintBotGuessing, but it is probably H+ and not H2.
72719view14:38, 3 December 2013AndraFixed curation issues
72718view14:38, 3 December 2013AndraFixed curation issues
72717view14:37, 3 December 2013AndraFixed curation issues
72660view12:55, 29 November 2013AndraModified description
72659view12:49, 29 November 2013AndraModified description
72658view12:38, 29 November 2013AndraOntology Term : 'parietal cell' added !
72657view12:36, 29 November 2013AndraFirst release
72656view12:26, 29 November 2013AndraPeriodical save, work in progress
72655view12:16, 29 November 2013AndraPeriodical save, work in progress
72654view12:06, 29 November 2013AndraPeriodical save, work in progress
72653view11:56, 29 November 2013AndraPeriodical save, work in progress
72652view11:46, 29 November 2013AndraPeriodical save, work in progress
72651view11:36, 29 November 2013AndraNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
ATP4AGeneProduct495 (Entrez Gene)
AcetylcholineMetabolite182 (Chemspider)
Bicarbonate ionMetabolite749 (Chemspider)
CCKBRGeneProduct887 (Entrez Gene)
CHRM1GeneProduct1128 (Entrez Gene)
Carbon dioxideMetabolite274 (Chemspider)
Chloride ionMetaboliteHMDB0000492 (HMDB)
GastrinGeneProductP01350 (Uniprot-TrEMBL)
HRH2GeneProduct3274 (Entrez Gene)
Histamine Metabolite753 (Chemspider)
HydrogenMetaboliteHMDB0059597 (HMDB)
PotassiumMetaboliteHMDB0000586 (HMDB)
WaterMetabolite937 (Chemspider)
ZincMetabolite22430 (Chemspider)

Annotated Interactions

No annotated interactions

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