Acetaminophen synthesis (Escherichia coli)
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Description
Synthetic biology approaches to acetaminophen production. The first reaction path in E.coli has been successfully tested experimentally. The second path in Synechocystis is proposed hypothetically by Menezes, et al. in a study considering synthetic biology approaches to resource utilization on future space missions.
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Ontology Terms
Bibliography
- Mizutani Y, Narikawa T, Satoh T, Sakurai N, Kaji H, Yamada S, Samejima T; ''A new UV method for serum gamma-glutamyltransferase assay using recombinant 4-aminobenzoate hydroxylase as a coupling enzyme.''; J Biochem, 1999 PubMed Europe PMC Scholia
- Menezes AA, Cumbers J, Hogan JA, Arkin AP; ''Towards synthetic biological approaches to resource utilization on space missions.''; J R Soc Interface, 2015 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
4-Aminophenol | Metabolite | HMDB0001169 (HMDB) | |
4-amino-4-deoxychorismate | Metabolite | CHEBI:35181 (ChEBI) | |
4ABH (muschroom) | GeneProduct | ||
Acetaminophen | Metabolite | HMDB0001859 (HMDB) | |
Ammonia | Metabolite | HMDB0000051 (HMDB) | |
Anthranilate | Metabolite | 227 (PubChem-compound) | |
Chorismate | Metabolite | HMDB0012199 (HMDB) | |
nhoA | GeneProduct | b1463 (Ensembl) | |
p-Aminobenzoic acid | Metabolite | HMDB0001392 (HMDB) | |
pabA | GeneProduct | b3360 (Ensembl) | |
pabB | GeneProduct | b1812 (Ensembl) | |
pabC | GeneProduct | b1096 (Ensembl) | |
trpE | GeneProduct | b1264 (Ensembl) |
Annotated Interactions
No annotated interactions