Apoptosis-related network due to altered Notch3 in ovarian cancer (Bos taurus)

From WikiPathways

Jump to: navigation, search
ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none NET1ERBB3TNFSERBP1APOECUL5SQSTM1TNFRSF10DRIPK2CUL1CDKN1AAKT1HSPB1CTNNA1HSPD1HELLSANXA5HDAC1NFKB1BCL3TRAF1NGFRAP1RNF7PTK2ETS1MAPK1CDKN1BRPS6KB1PPP2GBAXIN1SMAD7VIMPKN1IER3CSDACARD14NQO1GCLCJUNDF2RBIRC5THBS1TNFRSF21APPCASP7GGFBPP5ABL1PAK2SOCS3IL7RPTK2BVAV3ERN1GRP78Name: Apoptosis-related network due to altered Notch3 in ovarian cancerOrganism: Bos taurus


Description

Results of pathway analysis of apoptosis-related genes in OVCAR3 cells treated with Notch3 siRNA or control siRNA.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2864(79278) with a 96.0% conversion rate.

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Image:Curated.pngApproved version
Image:MissingXref.pngAnnotate nodes
Homology Converted

Ontology Terms

Pathway Ontology : classic metabolic pathway
 

Bibliography

  1. Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK; ''Notch3 pathway alterations in ovarian cancer.''; Cancer Res, 2014 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
108132
Approved
view10:30, 29 November 2019FehrhartOntology Term : 'cancer pathway' added !
80679view15:21, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
ABL1GeneProductENSBTAG00000017976 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:25
AKT1GeneProductENSBTAG00000017636 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:207
ANXA5GeneProductENSBTAG00000021746 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:308
APOEGeneProductENSBTAG00000010123 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:348
APPGeneProductENSBTAG00000017753 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:351
AXIN1GeneProductENSBTAG00000016577 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8312
BCL3ProteinENSBTAG00000009493 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:602
BIRC5GeneProductENSBTAG00000013573 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:332
CARD14GeneProductENSBTAG00000015261 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:79092
CASP7GeneProductENSBTAG00000006615 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:840
CDKN1AGeneProductENSBTAG00000008353 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1026
CDKN1BGeneProductENSBTAG00000018254 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1027
CSDAGeneProductENSBTAG00000009663 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8531
CTNNA1GeneProductENSBTAG00000014182 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1495
CUL1GeneProductENSBTAG00000008736 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8454
CUL5GeneProductENSBTAG00000012882 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8065
ERBB3GeneProductENSBTAG00000010444 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2065
ERN1GeneProductENSBTAG00000016799 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2081
ETS1GeneProductENSBTAG00000002341 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2113
F2RGeneProductENSBTAG00000020199 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2149
GCLCGeneProductENSBTAG00000015571 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2729
GGFBPP5GeneProductENSBTAG00000004150 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3084
GRP78GeneProductENSBTAG00000007662 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3309
HDAC1GeneProductENSBTAG00000012698 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3065
HELLSGeneProductENSBTAG00000005979 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3070
HSPB1GeneProductENSBTAG00000011969 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3315
HSPD1GeneProductENSBTAG00000012586 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3329
IER3GeneProductENSBTAG00000011358 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8870
IL7RGeneProductENSBTAG00000019975 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3575
JUNDGeneProduct
MAPK1GeneProductENSBTAG00000010312 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5594
NET1GeneProductENSBTAG00000007648 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10276
NFKB1GeneProductENSBTAG00000020270 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4790
NGFRAP1GeneProductENSBTAG00000006026 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:27018
NQO1GeneProductENSBTAG00000020632 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1728
PAK2GeneProductENSBTAG00000047856 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5062
PKN1GeneProductENSBTAG00000017037 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5585
PPP2GBGeneProduct
PTK2BGeneProductENSBTAG00000005958 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2185
PTK2GeneProductENSBTAG00000009578 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5747
RIPK2GeneProductENSBTAG00000015271 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8767
RNF7GeneProductENSBTAG00000002185 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9616
RPS6KB1GeneProductENSBTAG00000016851 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6198
SERBP1GeneProductENSBTAG00000012957 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:26135
SMAD7GeneProductENSBTAG00000012441 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4092
SOCS3GeneProductENSBTAG00000008441 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9021
SQSTM1GeneProductENSBTAG00000015591 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8878
THBS1GeneProductENSBTAG00000002006 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7057
TNFGeneProductENSBTAG00000025471 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7124
TNFRSF10DGeneProductENSBTAG00000047389 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8795
TNFRSF21GeneProductENSBTAG00000020054 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:27242
TRAF1GeneProductENSBTAG00000003012 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7185
VAV3GeneProductENSBTAG00000031575 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10451
VIMGeneProductENSBTAG00000018463 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7431

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP3126"
Personal tools