miRNA biogenesis (Bos taurus)

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Mature sequence hsa-miR-146a-5p Accession: MIMAT0000449Previous: hsa-miR-146;hsa-miR-146aMature sequence hsa-miR-146a-3pAccession: MIMAT0004608Previous: hsa-miR-146a*Stem-loop sequence hsa-mir-146a Accession: MI0000477 Previous: hsa-mir-1461, 2Transcriptionpre-miRNANucleuspri-miRNAsGTPXPO5RNA polymerase IIRANDROSHADICER1DGCR8CytoplasmDICER1TARBP2miRNA duplexDNApre-miRNA5'3'5'3'5'3'3'5'5'3'5'3'


Description

microRNA biogenesis + an example of a miRBase entry.

As an example immature hsa-mir-146a is shown

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2338(78504) with a 77.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Wienholds E, Plasterk RH; ''MicroRNA function in animal development.''; FEBS Lett, 2005 PubMed Europe PMC Scholia
  2. Yang JS, Phillips MD, Betel D, Mu P, Ventura A, Siepel AC, Chen KC, Lai EC; ''Widespread regulatory activity of vertebrate microRNA* species.''; RNA, 2011 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
117554view11:18, 21 May 2021EweitzModified title
106016view11:54, 16 August 2019MaintBotHMDB identifier normalization
80701view15:22, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
DGCR8GeneProductENSBTAG00000019869 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000128191
DICER1GeneProductENSBTAG00000012852 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000100697
DROSHAGeneProductENSBTAG00000017551 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000113360
GTPMetaboliteHMDB0001440 (HMDB)
RANGeneProductENSBTAG00000014223 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5901
RNA polymerase IIProtein
TARBP2ProteinENSBTAG00000000435 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q15633
XPO5GeneProductENSBTAG00000018970 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000124571
pri-miRNAsProtein

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP3140"
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