Nicotine activity on dopaminergic neurons (Bos taurus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none PDepolarizationSynaptic VesicleDopaminergic neuronThr75PPPP1R1BThr34PPPP1R1BPRKACADopamineSNARE ComplexCDK5TyrosinePPP1R1BDopamineADCY2ATPDopamineCa++GNAI1K+K+DOPANicotinePPP1CACa++cAMPNa+K+GNAI1DRD2GNB1DRD4GNG2DRD3CHRNA4CHRNB2GNG2GNB1CHRNA4CHRNB2CHRNA6CHRNA3KCNK9KCNK3THDDCSLC18A2Na+K+DRD2DRD4DRD3DopamineCHRNA4CHRNA5CHRNB2Name: Nicotine activity on dopaminergic neuronsLicense: CC BY 2.0Organism: Bos taurus


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP1602(78486) with a 91.0% conversion rate.

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Quality Tags

Ontology Terms

Pathway Ontology : nicotine pathway
Cell Type : dopaminergic neuron
 

Bibliography

  1. Cartier EA, Parra LA, Baust TB, Quiroz M, Salazar G, Faundez V, Egaña L, Torres GE; ''A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles.''; J Biol Chem, 2010 PubMed Europe PMC Scholia
  2. martin, grady; ''mine''; wikipathways.org, 1999 PubMed Europe PMC Scholia
  3. Eiden LE, Schäfer MK, Weihe E, Schütz B; ''The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine.''; Pflugers Arch, 2004 PubMed Europe PMC Scholia
  4. Kaltenbach M; ''[Conservative therapy of coronary heart disease].''; Verh Dtsch Ges Kreislaufforsch, 1975 PubMed Europe PMC Scholia
  5. Klein TE, Chang JT, Cho MK, Easton KL, Fergerson R, Hewett M, Lin Z, Liu Y, Liu S, Oliver DE, Rubin DL, Shafa F, Stuart JM, Altman RB; ''Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base.''; Pharmacogenomics J, 2001 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
137189view14:25, 28 February 2025EgonwModified description
117567view11:21, 21 May 2021EweitzModified title
106010view11:53, 16 August 2019MaintBotHMDB identifier normalization
80757view15:24, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
ADCY2GeneProductENSBTAG00000019210 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:108
ATPMetaboliteHMDB0000538 (HMDB)
CDK5GeneProductENSBTAG00000007766 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1020
CHRNA3GeneProductENSBTAG00000003130 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1136
CHRNA4GeneProductENSBTAG00000017198 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1137
CHRNA5GeneProductENSBTAG00000013657 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1138
CHRNA6GeneProductENSBTAG00000014056 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8973
CHRNB2GeneProductENSBTAG00000007517 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1141
Ca++MetaboliteHMDB0000464 (HMDB)
DDCGeneProductENSBTAG00000020869 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1644
DOPAMetaboliteHMDB0000181 (HMDB)
DRD2GeneProductENSBTAG00000010860 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1813
DRD3GeneProductENSBTAG00000002132 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1814
DRD4GeneProduct
DopamineMetaboliteHMDB0000073 (HMDB)
GNAI1GeneProductENSBTAG00000002714 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2770
GNB1GeneProductENSBTAG00000000215 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2782
GNG2GeneProductENSBTAG00000003043 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:54331
K+MetaboliteHMDB0000586 (HMDB)
KCNK3GeneProductENSBTAG00000018193 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3777
KCNK9GeneProductENSBTAG00000047488 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51305
Na+MetaboliteHMDB0000588 (HMDB)
NicotineMetaboliteHMDB0001934 (HMDB)
PPP1CAGeneProductENSBTAG00000040418 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5499
PPP1R1BGeneProductENSBTAG00000006035 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:84152
PRKACAGeneProductENSBTAG00000006642 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5566
SLC18A2GeneProductENSBTAG00000004739 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6571
SNARE ComplexGeneProduct
THGeneProductENSBTAG00000026768 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7054
TyrosineMetaboliteHMDB0000158 (HMDB)
cAMPMetaboliteHMDB0000058 (HMDB)

Annotated Interactions

No annotated interactions
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