Nicotine metabolism (Bos taurus)
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Liver cell
Nicotine iminium ion
CYP2A6
Cotinine N-oxide
Nicotine-Gluc
AOX1
Cotinine
3'-Hydroxycotinine
5'-Hydroxycotinine
Nicotine-N-oxide
Cotinine
CYP2A6
CYP2A6
Nornicotine
3'-Hydroxycotinine glucuronide
Nornicotine
Cotinineglucuronide
5'-Hydroxycotinine
UGT1A4
Nornicotine
Cotinineglucuronide
3'-Hydroxycotinine glucuronide
UGT1A9
Nicotine
Cotinine N-oxide
Nornicotine
FMO3
Nicotine-N-oxide
Nicotine-Gluc
Nicotine
3'-Hydroxycotinine
CYP2B6
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP1600(70113)
with a 87.0% conversion rate.
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Bibliography
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History
Compare
Revision
Action
Time
User
Comment
117574
view
11:22, 21 May 2021
Eweitz
Modified title
105959
view
11:49, 16 August 2019
MaintBot
HMDB identifier normalization
89936
view
13:45, 6 October 2016
Egonw
Modified description
80767
view
15:25, 30 June 2015
Mkutmon
New pathway
External references
DataNodes
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Name
Type
Database reference
Comment
3'-Hydroxycotinine glucuronide
Metabolite
HMDB0001204 (HMDB)
3'-Hydroxycotinine
Metabolite
HMDB0001390 (HMDB)
5'-Hydroxycotinine
Metabolite
HMDB0001427 (HMDB)
AOX1
GeneProduct
ENSBTAG00000009725 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:316
CYP2A6
GeneProduct
ENSBTAG00000047815 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1548
CYP2B6
GeneProduct
ENSBTAG00000003871 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1555
Cotinine N-oxide
Metabolite
HMDB0001411 (HMDB)
Cotinine
Metabolite
HMDB0001046 (HMDB)
Cotinineglucuronide
Metabolite
HMDB0001013 (HMDB)
FMO3
GeneProduct
ENSBTAG00000020597 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2328
Nicotine iminium ion
Metabolite
HMDB0001010 (HMDB)
Nicotine-Gluc
Metabolite
HMDB0001272 (HMDB)
Nicotine-N-oxide
Metabolite
HMDB0001497 (HMDB)
Nicotine
Metabolite
HMDB0001934 (HMDB)
Nornicotine
Metabolite
HMDB0001126 (HMDB)
UGT1A4
GeneProduct
ENSBTAG00000048275 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:54657
UGT1A9
GeneProduct
Annotated Interactions
No annotated interactions
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