Hydrochloric acid secretion in parietal cells (Bos taurus)

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1carbonate dehydratase activityVenous bloodStomach lumenPotassiumCCKBRZincHistamine AcetylcholineCHRM1ATP4ACarbon dioxideGASTChloride ionHRH2Bicarbonate ionWaterHydrogenBicarbonate ionHydrogenChloride ionPotassiumChloride ion


Description

Gastric parietal cells are stomach epithelial cells. They secrete gastric acid and intrinsic factor. This pathway is primarily based on https://en.wikipedia.org/wiki/Parietal_cell

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2597(78485) with a 100.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Murakami H, Sly WS; ''Purification and characterization of human salivary carbonic anhydrase.''; J Biol Chem, 1987 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
117598view11:36, 21 May 2021EweitzModified title
105939view11:47, 16 August 2019MaintBotHMDB identifier normalization
87648view08:54, 25 July 2016LindarieswijkOntology Term : 'acid-base homeostasis pathway' added !
80797view15:26, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATP4AGeneProductENSBTAG00000045598 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:495
AcetylcholineMetabolite182 (Chemspider)
Bicarbonate ionMetabolite749 (Chemspider)
CCKBRGeneProductENSBTAG00000005236 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:887
CHRM1GeneProductENSBTAG00000011579 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1128
Carbon dioxideMetabolite274 (Chemspider)
Chloride ionMetaboliteHMDB0000492 (HMDB)
GASTGeneProductENSBTAG00000017663 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P01350
HRH2GeneProductENSBTAG00000044071 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3274
Histamine Metabolite753 (Chemspider)
HydrogenMetaboliteHMDB0059597 (HMDB)
PotassiumMetaboliteHMDB0000586 (HMDB)
WaterMetabolite937 (Chemspider)
ZincMetabolite22430 (Chemspider)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP3204"
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