Please help improve this pathway by editing the description. You are allowed to use literature references as a source of inspiration, however please write your own text. Remove this tag when completed.
Approved version
The current version of this pathway was approved for data analysis by Marvin Martens.
Annotate nodes
Comment: 15 out of 66 DataNodes have a missing external reference. Check DataNode table at the bottom of the page.
Please help improve this pathway by annotating gene, protein and metabolite nodes.
Jordan VC; ''New insights into the metabolism of tamoxifen and its role in the treatment and prevention of breast cancer.''; Steroids, 2007 PubMedEurope PMCScholia
Jordan VC; ''Chemoprevention of breast cancer with selective oestrogen-receptor modulators.''; Nat Rev Cancer, 2007 PubMedEurope PMCScholia
Lazarus P, Blevins-Primeau AS, Zheng Y, Sun D; ''Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen.''; Ann N Y Acad Sci, 2009 PubMedEurope PMCScholia
Kaku T, Ogura K, Nishiyama T, Ohnuma T, Muro K, Hiratsuka A; ''Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4.''; Biochem Pharmacol, 2004 PubMedEurope PMCScholia
Ogura K, Ishikawa Y, Kaku T, Nishiyama T, Ohnuma T, Muro K, Hiratsuka A; ''Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4.''; Biochem Pharmacol, 2006 PubMedEurope PMCScholia
Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
Ontology Terms
Bibliography
History
External references
DataNodes
Annotated Interactions
No annotated interactions