miR-222 in exercise-induced cardiac growth (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Growth, Proliferation and Cardiac RepairExerciseCardiomyocyteCDKN1BHMBOX1MIR222HIPK2HIPK1Name: miR-222 in exercise-induced cardiac growthOrganism: Homo sapiens


Description

miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling. Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP3938).

Comments

HomologyMapper 
This pathway was inferred from Mus musculus pathway "miR-222 in Exercise-Induced Cardiac Growth", WP2928 revision 87837, with a 80.0% conversion rate.

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Quality Tags

Image:Curated.pngApproved version
Homology Converted

Ontology Terms

Pathway Ontology : Notch signaling pathway
 

Bibliography

  1. Liu X, Xiao J, Zhu H, Wei X, Platt C, Damilano F, Xiao C, Bezzerides V, Boström P, Che L, Zhang C, Spiegelman BM, Rosenzweig A; ''miR-222 Is Necessary for Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling.''; Cell Metab, 2015 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
137954
Approved
view20:53, 10 March 2025KhanspersModified description
120650view18:14, 22 December 2021Khanspersadded xref for mir222
118945view22:43, 4 June 2021EweitzOntology Term : 'microRNA pathway' added !
118944view22:41, 4 June 2021EweitzModified title
117790view14:06, 22 May 2021EweitzOntology Term : 'PW:0000808' removed !
117780view14:01, 22 May 2021EweitzOntology Term : 'microRNA pathway' added !
117779view14:01, 22 May 2021EweitzOntology Term : 'PW:0000004' removed !
105858view23:19, 15 August 2019KhanspersModified description
97682view14:11, 1 June 2018AMTanOntology Term : 'cardiac muscle cell' added !
90779view01:26, 14 December 2016KhanspersOntology Term : 'regulatory pathway' added !
90778view01:26, 14 December 2016KhanspersNew pathway

External references

DataNodes

Name  ↓Type  ↓Database reference  ↓Comment  ↓
CDKN1BGeneProductENSG00000111276 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000003031
HIPK1GeneProductENSG00000163349 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000008730
HIPK2GeneProductENSG00000064393 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000061436
HMBOX1GeneProductENSG00000147421 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000021972
MIR222RnaMI0000299 (miRBase Sequence) No homologues found for original id En:ENSMUSG00000065471

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP3938"
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