From WikiPathways
ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Inhibitors of Preadipocyte to Adipocyte Transition Transcription Factors/Modulators Growth Factors/Hormones Fully Differentiated Adipocyte Markers Miscellaneous Preadipocyte Differentiated adipocyte Adipocyte Secretory Products Possible Lipodystrophy Genes Insulin Action Genes Igf1 Ptgis Ppard Creb1 Mixl1 Gh Id3 Stat5a Stat5b Nr3c1 Ddit3 Lif Cebpb Cyp26a1 Cyp26b1 Rxra Rara Nr1h3 Lpl Fas Rbl1 Gata3 Gata2 Pparg Tnf Mif Tgfb1 Serpine1 Slc2a4 Scd1 Twist1 Fabp4 Rb1 Rbl2 Nsg1 E2f1 Sp1 Hmga1 Il6 Gadd45a Gadd45b Cebpa Cebpd Bmp1 Bmp2 Bmp3 Bmp4 E2f4 Foxo1 Klf5 Foxc2 Ppargc1a Ncoa2 Ppara Stat3 Stat2 Stat1 Stat6 Socs1 Socs3 Cntfr Lifr Il6st Ucp1 Wnt1 Smad3 Fzd1 Dvl1 Tcf1 Rxrg Frzb Ins1 Ins2 Trib3 Prlr Cugbp1 Hif1a Klf6 Klf7 Sfrp4 Ncor1 Ncor2 Ahr Klf15 Egr2 Ebf1 Epas1 Wwtr1 Gdf10 Irs1 LOC384783 Irs3 Irs4 Bscl2 Lmna Zmpste24 Lpin1 Lpin2 Lpin3 Pck1 Pck2 Dlk1 Ndn Wnt10b Wnt5b Gata4 Ncoa1 Nr2f1 Rora Nrip1 Plin Lipe Retn Adn Adfp Adpn Agt Pbef1 Spock1 Osm Catnb Agrp D10Ertd214e Lep Mef2a Mef2b Mef2c Mef2d Srebf1 Mbnl1 Adipoq Agpat2 Tle3 Name: Adipogenesis genes Last Modified: 5/9/2013 Organism: Mus musculus
Description
The different classes of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.
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Quality Tags
Approved version The current version of this pathway was approved for data analysis by Egon Willighagen .
Annotated lists Annotated lists of gene products are considered useful for analysis and for stimulating future pathway curation.
Ontology Terms
Bibliography
Villanueva CJ, Waki H, Godio C, Nielsen R, Chou WL, Vargas L, Wroblewski K, Schmedt C, Chao LC, Boyadjian R, Mandrup S, Hevener A, Saez E, Tontonoz P; ''TLE3 Is a Dual-Function Transcriptional Coregulator of Adipogenesis.''; Cell Metab, 2011 PubMed Europe PMC Scholia Rosen ED, Spiegelman BM; ''Molecular regulation of adipogenesis.''; Annu Rev Cell Dev Biol, 2000 PubMed Europe PMC Scholia History
External references
DataNodes
Annotated Interactions
No annotated interactions
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