Adipogenesis genes (Mus musculus)

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2Growth Factors/HormonesInsulin Action GenesInhibitors of Preadipocyte to Adipocyte TransitionTranscription Factors/ModulatorsAdipocyte Secretory ProductsPreadipocyteFully Differentiated Adipocyte MarkersDifferentiated adipocyteMiscellaneousPossible Lipodystrophy GenesAgtBmp1Mef2bKlf5RaraNr2f1Ncoa1Stat6Fabp4Ddit3Trib3Stat2GhLpin2Bmp2D10Ertd214eRb1NdnMef2cGata4RetnFoxc2Tcf1Tgfb1Irs1Mbnl1Nsg1Dlk1PtgisE2f4Ebf1AdipoqAhrWnt1MifIl6Nr1h3Socs3LepSfrp4Ncor1Creb1Agpat2Stat1Klf7CebpdGadd45bNr3c1Foxo1OsmSrebf1Lpin3LmnaPpargc1aFzd1Ins2Pck1PpardGata2Hmga1PpargEpas1Nrip1Klf15LipeWwtr1Pck2Twist1Bmp4Id3Serpine1Ins1Cyp26b1Ncoa2Wnt5bSmad3Sp1Cyp26a1FasPrlrMef2dKlf6RoraE2f1LplGdf10CebpaRxrgLifStat5bRxraDvl1Stat3Gata3Ucp1Pbef1Il6stCugbp1AgrpFrzbAdfpCebpbLifrIgf1AdnBmp3Scd1Zmpste24Mef2aLpin1Mixl1Spock1TnfCntfrIrs3PparaCatnbBscl2Hif1aNcor2AdpnGadd45aIrs4LOC384783Stat5aRbl1Wnt10bRbl2PlinSlc2a4Egr2Socs1Tle31


Description

The different classes of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Villanueva CJ, Waki H, Godio C, Nielsen R, Chou WL, Vargas L, Wroblewski K, Schmedt C, Chao LC, Boyadjian R, Mandrup S, Hevener A, Saez E, Tontonoz P; ''TLE3 Is a Dual-Function Transcriptional Coregulator of Adipogenesis.''; Cell Metab, 2011 PubMed Europe PMC Scholia
  2. Rosen ED, Spiegelman BM; ''Molecular regulation of adipogenesis.''; Annu Rev Cell Dev Biol, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
126310view17:29, 20 April 2023EgonwLicense is CCZero
87026view14:49, 15 July 2016MkutmonOntology Term : 'signaling pathway pertinent to development' added !
73875view20:50, 26 February 2014MaintBotModified title
72045view16:41, 24 October 2013Mkutmonupdated annotations
69771view11:58, 11 July 2013Mkutmonreplace annotation lines with graphical lines (instead of interactions)
63290view17:26, 9 May 2013MaintBotupdating gpml
42781view21:25, 29 April 2011Claudio.j.villanuevaIncluded new transcriptional regulator
41258view00:20, 2 March 2011MaintBotRemoved redundant pathway information and comments
37353view18:20, 28 May 2010KhanspersModified description
35353view09:05, 12 February 2010MartijnVanIerselModified description
35344view08:58, 12 February 2010MartijnVanIerseladded literature reference
28134view19:50, 27 January 2009KhanspersRemoved species from name
21620view11:32, 14 November 2008MaintBot[[Pathway:Mus musculus:Adipogenesis]] moved to [[Pathway:WP447]]: Moved to stable identifier
7886view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Adipogenesis]] moved to [[Pathway:Mus musculus:Adipogenesis]]: Renaming species
7568view16:00, 18 December 2007MaintBotfixed category names
7453view12:42, 4 November 2007MaintBotAdded categories to GPML
6411view22:18, 22 May 2007M.Pattigpml file for [[Mouse:Adipogenesis]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AdfpGeneProduct11520 (Entrez Gene)
AdipoqGeneProduct11450 (Entrez Gene)
AdnGeneProduct11537 (Entrez Gene)
AdpnGeneProduct116939 (Entrez Gene)
Agpat2GeneProduct67512 (Entrez Gene)
AgrpGeneProduct11604 (Entrez Gene)
AgtGeneProduct11606 (Entrez Gene)
AhrGeneProduct11622 (Entrez Gene)
Bmp1GeneProduct12153 (Entrez Gene)
Bmp2GeneProduct12156 (Entrez Gene)
Bmp3GeneProduct110075 (Entrez Gene)
Bmp4GeneProduct12159 (Entrez Gene)
Bscl2GeneProduct14705 (Entrez Gene)
CatnbGeneProduct12387 (Entrez Gene)
CebpaGeneProduct12606 (Entrez Gene)
CebpbGeneProduct12608 (Entrez Gene)
CebpdGeneProductENSMUSG00000071637 (Ensembl)
CntfrGeneProduct12804 (Entrez Gene)
Creb1GeneProduct12912 (Entrez Gene)
Cugbp1GeneProduct13046 (Entrez Gene)
Cyp26a1GeneProduct13082 (Entrez Gene)
Cyp26b1GeneProduct232174 (Entrez Gene)
D10Ertd214eGeneProduct52637 (Entrez Gene)
Ddit3GeneProduct13198 (Entrez Gene)
Dlk1GeneProduct13386 (Entrez Gene)
Dvl1GeneProduct13542 (Entrez Gene)
E2f1GeneProduct13555 (Entrez Gene)
E2f4GeneProduct104394 (Entrez Gene)
Ebf1GeneProduct13591 (Entrez Gene)
Egr2GeneProduct13654 (Entrez Gene)
Epas1GeneProduct13819 (Entrez Gene)
Fabp4GeneProduct11770 (Entrez Gene)
FasGeneProduct14102 (Entrez Gene)
Foxc2GeneProduct14234 (Entrez Gene)
Foxo1GeneProduct56458 (Entrez Gene)
FrzbGeneProduct20378 (Entrez Gene)
Fzd1GeneProduct14362 (Entrez Gene)
Gadd45aGeneProduct13197 (Entrez Gene)
Gadd45bGeneProduct17873 (Entrez Gene)
Gata2GeneProduct14461 (Entrez Gene)
Gata3GeneProduct14462 (Entrez Gene)
Gata4GeneProduct14463 (Entrez Gene)
Gdf10GeneProduct14560 (Entrez Gene)
GhGeneProduct14599 (Entrez Gene)
Hif1aGeneProduct15251 (Entrez Gene)
Hmga1GeneProduct15361 (Entrez Gene)
Id3GeneProduct15903 (Entrez Gene)
Igf1GeneProduct16000 (Entrez Gene)
Il6GeneProduct16193 (Entrez Gene)
Il6stGeneProduct16195 (Entrez Gene)
Ins1GeneProduct16333 (Entrez Gene)
Ins2GeneProduct16334 (Entrez Gene)
Irs1GeneProduct16367 (Entrez Gene)
Irs3GeneProduct16369 (Entrez Gene)
Irs4GeneProduct16370 (Entrez Gene)
Klf15GeneProduct66277 (Entrez Gene)
Klf5GeneProduct12224 (Entrez Gene)
Klf6GeneProduct23849 (Entrez Gene)
Klf7GeneProduct93691 (Entrez Gene)
LOC384783GeneProduct384783 (Entrez Gene)
LepGeneProduct16846 (Entrez Gene)
LifGeneProduct16878 (Entrez Gene)
LifrGeneProduct16880 (Entrez Gene)
LipeGeneProduct16890 (Entrez Gene)
LmnaGeneProduct16905 (Entrez Gene)
Lpin1GeneProduct14245 (Entrez Gene)
Lpin2GeneProduct64898 (Entrez Gene)
Lpin3GeneProduct64899 (Entrez Gene)
LplGeneProduct16956 (Entrez Gene)
Mbnl1GeneProduct56758 (Entrez Gene)
Mef2aGeneProduct17258 (Entrez Gene)
Mef2bGeneProduct17259 (Entrez Gene)
Mef2cGeneProduct17260 (Entrez Gene)
Mef2dGeneProduct17261 (Entrez Gene)
MifGeneProduct17319 (Entrez Gene)
Mixl1GeneProduct27217 (Entrez Gene)
Ncoa1GeneProduct17977 (Entrez Gene)
Ncoa2GeneProduct17978 (Entrez Gene)
Ncor1GeneProduct20185 (Entrez Gene)
Ncor2GeneProduct20602 (Entrez Gene)
NdnGeneProduct17984 (Entrez Gene)
Nr1h3GeneProduct22259 (Entrez Gene)
Nr2f1GeneProduct13865 (Entrez Gene)
Nr3c1GeneProduct14815 (Entrez Gene)
Nrip1GeneProduct268903 (Entrez Gene)
Nsg1GeneProduct18196 (Entrez Gene)
OsmGeneProduct18413 (Entrez Gene)
Pbef1GeneProduct59027 (Entrez Gene)
Pck1GeneProduct18534 (Entrez Gene)
Pck2GeneProduct74551 (Entrez Gene)
PlinGeneProduct103968 (Entrez Gene)
PparaGeneProduct19013 (Entrez Gene)
PpardGeneProduct19015 (Entrez Gene)
PpargGeneProduct19016 (Entrez Gene)
Ppargc1aGeneProduct19017 (Entrez Gene)
PrlrGeneProduct19116 (Entrez Gene)
PtgisGeneProduct19223 (Entrez Gene)
RaraGeneProduct19401 (Entrez Gene)
Rb1GeneProduct19645 (Entrez Gene)
Rbl1GeneProduct19650 (Entrez Gene)
Rbl2GeneProduct19651 (Entrez Gene)
RetnGeneProduct57264 (Entrez Gene)
RoraGeneProduct19883 (Entrez Gene)
RxraGeneProduct20181 (Entrez Gene)
RxrgGeneProduct20183 (Entrez Gene)
Scd1GeneProduct20249 (Entrez Gene)
Serpine1GeneProduct18787 (Entrez Gene)
Sfrp4GeneProduct20379 (Entrez Gene)
Slc2a4GeneProduct20528 (Entrez Gene)
Smad3GeneProduct17127 (Entrez Gene)
Socs1GeneProduct12703 (Entrez Gene)
Socs3GeneProduct12702 (Entrez Gene)
Sp1GeneProduct20683 (Entrez Gene)
Spock1GeneProduct20745 (Entrez Gene)
Srebf1GeneProduct20787 (Entrez Gene)
Stat1GeneProduct20846 (Entrez Gene)
Stat2GeneProduct20847 (Entrez Gene)
Stat3GeneProduct20848 (Entrez Gene)
Stat5aGeneProduct20850 (Entrez Gene)
Stat5bGeneProduct20851 (Entrez Gene)
Stat6GeneProduct20852 (Entrez Gene)
Tcf1GeneProduct21405 (Entrez Gene)
Tgfb1GeneProduct21803 (Entrez Gene)
Tle3GeneProduct21887 (Entrez Gene)
TnfGeneProduct21926 (Entrez Gene)
Trib3GeneProduct228775 (Entrez Gene)
Twist1GeneProduct22160 (Entrez Gene)
Ucp1GeneProduct22227 (Entrez Gene)
Wnt10bGeneProduct22410 (Entrez Gene)
Wnt1GeneProduct22408 (Entrez Gene)
Wnt5bGeneProduct22419 (Entrez Gene)
Wwtr1GeneProduct97064 (Entrez Gene)
Zmpste24GeneProduct230709 (Entrez Gene)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP447"
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