Peptidoglycan cytoplasmic synthesis and recycling pathways (Escherichia coli)

From WikiPathways

Jump to: navigation, search
1, 2additional periplasmic enzymes (degradation)L-Ala-gamma-D-Glu-meso-DAP-D-AlaglmSmurFTonB-dependent uptake?D-AlaglmUglmManhMurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-AlaglutaminePeriplasmExtracellular SpaceCytoplasmD-glucosamine-6-phosphateUDP-MurNAc-L-AlaL-glutamateD-Ala-D-AlaDiaminopimelic acidPenicillin-binding protein 1CL-alaninePenicillin-binding protein 1BUndecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineUTPD-alanineUndecaprenyl phosphateGlucosamine-1PUND-PP-MurNAc-L-Ala-D-Glu-meso-DAP-D-Ala-D-AlaUDP-MurNAc-L-Ala-D-GluUndecaprenyl pyrophosphateFructose-6-phosphateD-glutamateUDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAPUDP-GlcNAcUDP-MurNAcUndecaprenyl-diphosphataseUDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-AlaPenicillin-binding protein 1AphosphoenolpyruvateUDP-GlcNAc-enolpyruvateNADPHN-acetylglucosamine-1-phosphatePeptidoglycan LayerAcetyl-CoAL-alanineGlcNAc-6-PMurNAc 6-phosphateGlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-AlaMurNAcPenicillin-binding protein 2(Peptidoglycan D,D-transpeptidase MrdA}Penicillin-binding protein 3(Peptidoglycan D,D-transpeptidase FtsI)glmUmurEmurDmurCmurBmurAmurGmraYddlBdadXalrmurIampGmplmurJftsWmtgAmurPanmKmurQnagAnagBnagK1,6-anhMurNAcGlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-AlanagZGlcNAc1,6-anhydro-N-acetylmuramyl-L-alanine amidase (AmpD)L-Ala-gamma-D-Glu-meso-DAPMurein tetrapeptide carboxypeptidase (LdcA)additional periplasmic enzymes (synthesis)


Description

PG cytoplasmic synthesis and recycling pathways in E. coli

Comments

 
NOTE: Cytoplasmic pathways only. Membrane & periplasmic pathways are incomplete.

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. Hélène Barreteau, Andreja Kovac, Audrey Boniface, Matej Sova, Stanislav Gobec, Didier Blanot; ''Cytoplasmic steps of peptidoglycan biosynthesis ''; FEMS Microbiol Rev., 2008 PubMed Europe PMC Scholia
  2. Christoph Mayer, Robert Maria Kluj, Maraike Mühleck, Axel Walter, Sandra Unsleber, Isabel Hottmann, Marina Borisova; ''Bacteria's different ways to recycle their own cell wall''; Int J Med Microbiol., 2019 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123880view10:45, 23 August 2022EgonwMissed one
123879view10:44, 23 August 2022EgonwReplaced a PubChem identifier with that of the neutral compound, with Wikidata mapping
116278view04:49, 26 April 2021KhanspersOntology Term : 'peptidoglycan biosynthetic pathway' added !
116273view15:09, 25 April 2021EgonwUpdated Uniprot-SwissProt to Uniprot-TrEMBL
115641view13:02, 3 March 2021EgonwCorrected the type of two metabolites (with ChEBI id)
115640view12:57, 3 March 2021EgonwModified title
115496view12:47, 24 February 2021Jpg64New pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1,6-anhMurNAcMetaboliteCHEBI:40666 (ChEBI)
1,6-anhydro-N-acetylmuramyl-L-alanine amidase (AmpD)ProteinP13016 (Uniprot-TrEMBL)
Acetyl-CoAMetaboliteHMDB01206 (HMDB)
D-Ala-D-AlaMetaboliteCHEBI:16576 (ChEBI)
D-AlaMetabolite71080 (PubChem-compound)
D-alanineMetaboliteCHEBI:15570 (ChEBI)
D-glucosamine-6-phosphateMetaboliteCHEBI:20995 (ChEBI)
D-glutamateMetaboliteCHEBI:29986 (ChEBI)
Diaminopimelic acidMetaboliteHMDB01370 (HMDB)
Fructose-6-phosphateMetaboliteCHEBI:15946 (ChEBI)
GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-AlaMetabolite163626 (PubChem-compound)
GlcNAc-6-PMetabolite150941 (PubChem-compound)
GlcNAcMetaboliteCHEBI:506227 (ChEBI)
Glucosamine-1PMetaboliteHMDB01109 (HMDB)
L-Ala-gamma-D-Glu-meso-DAP-D-AlaMetabolite51351779 (PubChem-compound)
L-Ala-gamma-D-Glu-meso-DAPMetabolite51351754 (PubChem-compound)
L-alanineMetaboliteCHEBI:16977 (ChEBI)
L-glutamateMetaboliteCHEBI:29985 (ChEBI)
MurNAc 6-phosphateMetaboliteCHEBI:47968 (ChEBI)
MurNAcMetabolite5462244 (PubChem-compound)
Murein tetrapeptide carboxypeptidase (LdcA)ProteinP76008 (Uniprot-TrEMBL)
N-acetylglucosamine-1-phosphateMetaboliteCHEBI:16446 (ChEBI)
NADPHMetaboliteHMDB00221 (HMDB)
Penicillin-binding protein 1AProteinP02918 (Uniprot-TrEMBL)
Penicillin-binding protein 1BProteinP02919 (Uniprot-TrEMBL)
Penicillin-binding protein 1CProteinP76577 (Uniprot-TrEMBL)
Penicillin-binding protein 2 (Peptidoglycan D,D-transpeptidase MrdA}ProteinQ2TL65 (Uniprot-TrEMBL)
Penicillin-binding protein 3 (Peptidoglycan D,D-transpeptidase FtsI)ProteinP0AD68 (Uniprot-TrEMBL)
Peptidoglycan LayerMetaboliteCHEBI:8005 (ChEBI)
TonB-dependent uptake?Protein
UDP-GlcNAc-enolpyruvateMetaboliteCHEBI:68483 (ChEBI)
UDP-GlcNAcMetaboliteCHEBI:16264 (ChEBI)
UDP-MurNAc-L-Ala-D-GluMetaboliteCHEBI:16970 (ChEBI)
UDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-AlaMetaboliteCHEBI:18199 (ChEBI)
UDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAPMetaboliteCHEBI:28639 (ChEBI)
UDP-MurNAc-L-AlaMetabolite5490066 (PubChem-compound)
UDP-MurNAcMetaboliteCHEBI:70765 (ChEBI)
UND-PP-MurNAc-L-Ala-D-Glu-meso-DAP-D-Ala-D-AlaMetabolite46173752 (PubChem-compound)
UTPMetaboliteCHEBI:46398 (ChEBI)
Undecaprenyl phosphateMetaboliteCHEBI:16141 (ChEBI)
Undecaprenyl pyrophosphateMetaboliteCHEBI:17047 (ChEBI)
Undecaprenyl-diphosphataseProteinP60932 (Uniprot-TrEMBL)
Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineMetaboliteCHEBI:28138 (ChEBI)
alrGeneProductP0A6B4 (Uniprot-TrEMBL)
ampGGeneProductP0AE16 (Uniprot-TrEMBL)
anhMurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-AlaMetabolite
anmKGeneProductP77570 (Uniprot-TrEMBL)
dadXGeneProductP29012 (Uniprot-TrEMBL)
ddlBGeneProductP07862 (Uniprot-TrEMBL)
ftsWGeneProductP0ABG4 (Uniprot-TrEMBL)
glmMGeneProductP31120 (Uniprot-TrEMBL)
glmSGeneProductP17169 (Uniprot-TrEMBL)
glmUGeneProductP0ACC7 (Uniprot-TrEMBL)
glutamineMetaboliteCHEBI:28300 (ChEBI)
mplGeneProductP37773 (Uniprot-TrEMBL)
mraYGeneProductP0A6W3 (Uniprot-TrEMBL)
mtgAGeneProductP46022 (Uniprot-TrEMBL)
murAGeneProductP0A749 (Uniprot-TrEMBL)
murBGeneProductP08373 (Uniprot-TrEMBL)
murCGeneProductP17952 (Uniprot-TrEMBL)
murDGeneProductP14900 (Uniprot-TrEMBL)
murEGeneProductP22188 (Uniprot-TrEMBL)
murFGeneProductP11880 (Uniprot-TrEMBL)
murGGeneProductP17443 (Uniprot-TrEMBL)
murIGeneProductP22634 (Uniprot-TrEMBL)
murJGeneProductP0AF16 (Uniprot-TrEMBL)
murPGeneProductP77272 (Uniprot-TrEMBL)
murQGeneProductP76535 (Uniprot-TrEMBL)
nagAGeneProductP0AF18 (Uniprot-TrEMBL)
nagBGeneProductP0A759 (Uniprot-TrEMBL)
nagKGeneProductP75959 (Uniprot-TrEMBL)
nagZGeneProductP75949 (Uniprot-TrEMBL)
phosphoenolpyruvateMetaboliteCHEBI:58702 (ChEBI)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5060"
Personal tools