NIPBL role in DNA damage - Cornelia de Lange syndrome (Homo sapiens)

From WikiPathways

Jump to: navigation, search
1122222212ICLCBX3NIPBLATMATRNIPBLHistone H2AXRNF8RNF168MDC1NIPBL role in DNA damage2, 3DSBDSB2ICLRNF8RNF168UbiquitinLegendChromatidDSBRecruitmentHistone H2AXMDC11RNF1681RNF8222ICL2Interstrand cross linkDSBDouble strand break


Description

Recruitment of cohesin subunit NIPBL after DNA damage.

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. Oka Y, Suzuki K, Yamauchi M, Mitsutake N, Yamashita S; ''Recruitment of the cohesin loading factor NIPBL to DNA double-strand breaks depends on MDC1, RNF168 and HP1γ in human cells.''; Biochem Biophys Res Commun, 2011 PubMed Europe PMC Scholia
  2. Bot C, Pfeiffer A, Giordano F, Manjeera DE, Dantuma NP, Ström L; ''Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.''; J Cell Sci, 2017 PubMed Europe PMC Scholia
  3. Oka Y, Suzuki K, Yamauchi M, Mitsutake N, Yamashita S; ''Recruitment of the cohesin loading factor NIPBL to DNA double-strand breaks depends on MDC1, RNF168 and HP1γ in human cells.''; Biochem Biophys Res Commun, 2011 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
129305view13:47, 26 March 2024MkutmonOntology Term : 'disease pathway' added !
128298view04:13, 30 January 2024EweitzLess margin
128297view04:12, 30 January 2024EweitzPlace legend at right of diagram, per convention
128296view04:09, 30 January 2024EweitzFurther economize layout
128295view03:31, 30 January 2024EweitzFurther economize layout
128294view03:13, 30 January 2024EweitzRefine legend, economize layout, standardize case
125320view21:50, 31 January 2023LarsgwFix reference bp:ID
119393view10:46, 27 June 2021EweitzOntology Term : 'Cornelia de Lange syndrome' added !
119392view10:46, 27 June 2021EweitzModified title
119109view12:38, 17 June 2021IrkilmezANew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATMGeneProductENSG00000149311 (Ensembl)
ATRGeneProductENSG00000175054 (Ensembl)
CBX3GeneProductENSG00000122565 (Ensembl)
Histone H2AXProteinP16104 (Uniprot-TrEMBL)
MDC1GeneProductENSG00000137337 (Ensembl)
NIPBLGeneProductENSG00000164190 (Ensembl)
RNF168GeneProductENSG00000163961 (Ensembl)
RNF8GeneProductENSG00000112130 (Ensembl)

Annotated Interactions

No annotated interactions

Personal tools