Lung pathology of COVID-19 (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Airway epithelial cellSARS-CoV-2NucleusCell deathIncreased in serum andbronchoalveolar lavage fluidCGASIFIH1DDX58MAVSNFKB1STING1TBK1IRF3TLR8TLR7TLR3IL6CCL2TNFIFN-ICXCL10IFN-IIIL1BCSF2IL18CXCL8CXCL9CXCL11IRF3NFKB1Name: Lung pathology of COVID-19Organism: Homo sapiens


Description

Beginning of a pathway on the Lung Pathology of COVID-19 based on a figure in a paper (Reference 1)

Comments

 
This pathway is based on figure 4 of Ref 1

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Quality Tags

Image:Wplogo_31.pngCommunity: COVID-19
Image:Curated.pngApproved version

Ontology Terms

Pathway Ontology : RNA degradation pathway
 

Bibliography

  1. Harrison AG, Lin T, Wang P; ''Mechanisms of SARS-CoV-2 Transmission and Pathogenesis.''; Trends Immunol, 2020 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
128308
COVID
Approved
view22:10, 30 January 2024EweitzOntology Term : 'epithelial cell' added !
128307view14:39, 30 January 2024Mkutmonchanged text to labels
120619view23:32, 18 December 2021EweitzLabel group of genes
120618view17:59, 18 December 2021EweitzRemove "Golgi" label due to WP-PathVisio graphics issue
120617view17:57, 18 December 2021EweitzFix WP-PathVisio graphics issue; label organelles, virus
120616view13:08, 18 December 2021EweitzUse official gene symbol, STING1
120615view13:04, 18 December 2021EweitzTighten graphics, refine datanodes, case
120379view23:48, 29 November 2021EweitzOntology Term : 'COVID-19' added !
120378view23:47, 29 November 2021EweitzModified title
120328view16:04, 26 November 2021XNautsNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
CCL2GeneProductENSG00000108691 (Ensembl)
CGASGeneProductENSG00000164430 (Ensembl)
CSF2GeneProductENSG00000164400 (Ensembl)
CXCL10GeneProductENSG00000169245 (Ensembl)
CXCL11GeneProductENSG00000169248 (Ensembl)
CXCL8MetaboliteCHEBI:138181 (ChEBI)
CXCL9GeneProductENSG00000138755 (Ensembl)
DDX58GeneProductENSG00000107201 (Ensembl)
IFIH1GeneProductENSG00000115267 (Ensembl)
IFN-II PF00714 (Pfam)
IFN-IPF00143 (Pfam)
IL18GeneProductENSG00000150782 (Ensembl)
IL1BGeneProductENSG00000125538 (Ensembl)
IL6GeneProductENSG00000136244 (Ensembl)
IRF3GeneProductENSG00000126456 (Ensembl)
MAVSGeneProductENSG00000088888 (Ensembl)
NFKB1GeneProductENSG00000109320 (Ensembl)
STING1GeneProductENSG00000184584 (Ensembl)
TBK1GeneProductENSG00000183735 (Ensembl)
TLR3GeneProductENSG00000164342 (Ensembl)
TLR7GeneProductENSG00000196664 (Ensembl)
TLR8GeneProductENSG00000101916 (Ensembl)
TNFGeneProductENSG00000232810 (Ensembl)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5146"
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