Lac-Phe pathway (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none L-phenylalanineABCC5(S)-lactateLac-PheCNDP2Lac-PheName: Lac-Phe pathwayOrganism: Homo sapiens


Description

Lac-Phe is formed by CNDP2 and exported outside the cell, into the blood circulation by ABCC5. It is linked to food intake and obesity, where it is increased after exercise and suppresses food intake.

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Quality Tags

Image:Curated.pngApproved version

Ontology Terms

 

Bibliography

  1. ''''; , PubMed Europe PMC Scholia
  2. ''''; , PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123034
Approved
view07:06, 20 June 2022EgonwRemoved RHEA:
123027view08:38, 18 June 2022EgonwOntology Term : 'classic metabolic pathway' added !
123026view08:38, 18 June 2022EgonwModified description
123024view08:37, 18 June 2022EgonwOntology Term : 'signaling pathway' added !
123023view08:37, 18 June 2022EgonwOntology Term : 'obesity pathway' added !
123021view08:36, 18 June 2022EgonwModified description
123017view06:59, 18 June 2022EgonwNew pathway

External references

DataNodes

Name  ↓Type  ↓Database reference  ↓Comment  ↓
(S)-lactateMetabolite16651 (ChEBI)
ABCC5GeneProductO15440 (Uniprot-TrEMBL)
CNDP2ProteinQ96KP4 (Uniprot-TrEMBL)
L-phenylalanineMetabolite58095 (ChEBI)
Lac-PheMetabolite167456 (ChEBI)

Annotated Interactions

Source  ↓Target  ↓Type  ↓Database reference  ↓Comment  ↓
(S)-lactateLac-Phemim-conversion66724 (Rhea)
Lac-PheLac-Phe66720 (Rhea)
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5239"
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