Exercise-induced circadian regulation (Mus musculus)

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1OthermSCNpStructural/CytoskeletonmHrts LvrspPermLvrs,pE-BoxmLvrsmSCNpRev-erbaNucleusmHrtsCry2mHrts mLvrsmHrts mLvrs,p mSCNpTranscriptionmLvrs,p SCNpmHrts mLvrs, mSCNpmLvrs,pmLvrsmHrtsChaperonemLvrpmHrts mLvrsmHrtsCell CyclemLvrpmHrtsSignalingmLvrsmHrtsmLvrsmLvrp mSCNpmLvrs,pmHrtsmHrts mLvrs,p mSCNmLvrsmHrtsmHrtsmHrtsPer2mLvrpmLvrp mSCNpMetabolismCry1mHrtsmSCNpCrymLvrsemLvrs,pmSCNpmHrts mLvrpmSCNpmLvrpmSCNpmLvrs,pmLvrpmHrtsProtein ModificationmHrtsmLvrpDNA/RNA BindingPer1mHrts mLvrs,pEif4g2Ppp1r3cTob1Cry1Gstp2ArntlNr1d1PigfQkEtv6Hist1h2bnPpp2cbD14Ertd171eZfrTubb4Cbx3Ucp3Dazap2Myf6Idi1Per1Sumo3Per2PuraHerpud1Sumo1CebpbSf3a3Ugp2OazinHspa8Cry2Btg1Dnaja1Nr1d2H2-DMaCldn5Ncoa4VapaClockMap3k7ip2Nckap1Gfra1G0s2RbpmsBteb1Gstm3D5Ertd593ePsma4E-BoxE-BoxE-BoxE-Box


Time- and exercise-dependent gene regulation in human skeletal muscle, http://genomebiology.com/2003/4/10/R61 Mouse genes regulated in the diurnal (inferred from human) and compared with mouse genes that display circadian regulation in mouse heart and liver (Panda 2002, Storch 2002), and SCN (Panda 2002). The 608 significantly regulated (P < 0.05) hSkM genes identified in the diurnal comparison (0800 h and 2000 h) were subjected to an additional statistical filter of absolute fold change > 20% (n = 239) and linked to mouse circadianly regulated orthologues. This pathway represents the resultant 44 putative hSkM circadianly regulated genes; L, promoter for the light-responsive element; E, E-box (Clock/Bmal1 promoter). Orthologue information is denoted to the left of the gene boxes: mHrts and mLvrs, mouse orthologue was circadianly regulated as described (Storch 2002) in mouse heart or liver, respectively; mLvrp and mSCNp, mouse orthologue was diurnally regulated as described (Panda 2002) in mouse liver or SCN, respectively.

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  1. Zambon AC, McDearmon EL, Salomonis N, Vranizan KM, Johansen KL, Adey D, Takahashi JS, Schambelan M, Conklin BR; ''Time- and exercise-dependent gene regulation in human skeletal muscle.''; Genome Biol, 2003 PubMed Europe PMC Scholia


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117882view10:21, 23 May 2021EweitzModified title
95033view17:43, 3 November 2017KhanspersModified description
91908view21:04, 3 April 2017KhanspersOntology Term : 'skeletal muscle fiber' added !
91907view21:02, 3 April 2017KhanspersOntology Term : 'skeletal muscle fiber' added !
91906view21:02, 3 April 2017Khanspersadded lit ref
91905view21:01, 3 April 2017Khanspersremoved GenMAPP comment
91904view21:00, 3 April 2017KhanspersModified description
91903view20:59, 3 April 2017Khanspersremoved GenMAPP comment
88050view13:45, 25 July 2016SusanOntology Term : 'regulatory pathway' added !
78411view10:25, 7 January 2015MaintBotadded missing graphIds
69890view18:49, 11 July 2013AlexanderPicoModified title
69782view12:43, 11 July 2013Mkutmonuse cellular compartment nucleus
69781view12:41, 11 July 2013Mkutmonfixed unconnected lines
69127view18:15, 8 July 2013MaintBotUpdated to 2013 gpml schema
41312view00:24, 2 March 2011MaintBotRemoved redundant pathway information and comments
33686view21:44, 3 December 2009KhanspersAdded connectors
29533view10:57, 12 May 2009EveloCorrected title!
21824view11:32, 14 November 2008MaintBot[[Pathway:Mus musculus:Circadian Exercise]] moved to [[Pathway:WP544]]: Moved to stable identifier
7962view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Circadian Exercise]] moved to [[Pathway:Mus musculus:Circadian Exercise]]: Renaming species
7605view16:03, 18 December 2007MaintBotfixed category names
7462view12:42, 4 November 2007MaintBotAdded categories to GPML
6426view22:18, 22 May 2007A.C.Zambongpml file for [[Mouse:Circadian_Exercise]]

External references


View all...
NameTypeDatabase referenceComment
ArntlGeneProduct11865 (Entrez Gene)
Bteb1GeneProduct16601 (Entrez Gene) 93527 at
Btg1GeneProduct12226 (Entrez Gene) 93104 at
Cbx3GeneProduct12417 (Entrez Gene) 100405 at
CebpbGeneProduct12608 (Entrez Gene) 92925 at
Cldn5GeneProduct12741 (Entrez Gene) 104516 at
ClockGeneProduct12753 (Entrez Gene)
Cry1GeneProduct12952 (Entrez Gene)
Cry2GeneProduct12953 (Entrez Gene)
D14Ertd171eGeneProduct238988 (Entrez Gene) 93829 at
D5Ertd593eGeneProduct52331 (Entrez Gene) 104116 at
Dazap2GeneProduct23994 (Entrez Gene) 94454 at
Dnaja1GeneProduct15502 (Entrez Gene) 97261 at
Eif4g2GeneProduct13690 (Entrez Gene) 100535 at
Etv6GeneProduct14011 (Entrez Gene) 93866 s at
G0s2GeneProduct14373 (Entrez Gene) 97531 at
Gfra1GeneProduct14585 (Entrez Gene) 93872 at
Gstm3GeneProduct14864 (Entrez Gene) 97681 f at
Gstp2GeneProduct14869 (Entrez Gene) 99583 at
H2-DMaGeneProduct14998 (Entrez Gene) 162346 f at
Herpud1GeneProduct64209 (Entrez Gene) 95057 at
Hist1h2bnGeneProduct319187 (Entrez Gene) 93833 s at
Hspa8GeneProduct15481 (Entrez Gene) 96564 at
Idi1GeneProduct319554 (Entrez Gene) 96269 at
Map3k7ip2GeneProduct68652 (Entrez Gene) 160309 at
Myf6GeneProduct17878 (Entrez Gene) 102265 at
Nckap1GeneProduct50884 (Entrez Gene) 95508 at
Ncoa4GeneProduct27057 (Entrez Gene) 97843 at
Nr1d1GeneProduct217166 (Entrez Gene)
Nr1d2GeneProduct353187 (Entrez Gene) 99076 at
OazinGeneProduct54375 (Entrez Gene) 101002 at
Per1GeneProduct18626 (Entrez Gene)
Per2GeneProduct18627 (Entrez Gene)
PigfGeneProduct18701 (Entrez Gene) 104725 at
Ppp1r3cGeneProduct53412 (Entrez Gene) 93933 at
Ppp2cbGeneProduct19053 (Entrez Gene) 101101 at
Psma4GeneProduct26441 (Entrez Gene) 97459 at
PuraGeneProduct19290 (Entrez Gene) 103501 at
QkGeneProduct19317 (Entrez Gene) 95096 at
RbpmsGeneProduct19663 (Entrez Gene) 103888 at
Sf3a3GeneProduct75062 (Entrez Gene) 96029 at
Sumo1GeneProduct22218 (Entrez Gene) 101091 at
Sumo3GeneProduct20610 (Entrez Gene) 95424 at
Tob1GeneProduct22057 (Entrez Gene) 99532 at
Tubb4GeneProduct22153 (Entrez Gene) 94835 f at
Ucp3GeneProduct22229 (Entrez Gene) 93392 at
Ugp2GeneProduct216558 (Entrez Gene) 94481 at
VapaGeneProduct30960 (Entrez Gene) 94889 at
ZfrGeneProduct22763 (Entrez Gene) 104050 at

Annotated Interactions

No annotated interactions

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