Inflammation is a protective response to infection by the immune system that requires communication between different classes of immune cells to coordinate their actions. Acute inflammation is an important part of the immune response, but chronic inappropriate inflammation can lead to destruction of tissues in autoimmune disorders and perhaps neurodegenerative or cardiovascular disease. Secreted cytokine proteins provide signals between immune cells to coordinate the inflammatory response.
Sources: [BioCarta](http://www.biocarta.com/pathfiles/h_inflamPathway.asp).
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Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway WP530(79331) with a 89.0% conversion rate.
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