Monoamine GPCRs (Homo sapiens)
From WikiPathways
Description
G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: Wikipedia
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Ontology Terms
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DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
ADRA1A | GeneProduct | 148 (Entrez Gene) | |
ADRA1B | GeneProduct | 147 (Entrez Gene) | |
ADRA1D | GeneProduct | 146 (Entrez Gene) | |
ADRA2A | GeneProduct | 150 (Entrez Gene) | |
ADRA2B | GeneProduct | 151 (Entrez Gene) | |
ADRA2C | GeneProduct | 152 (Entrez Gene) | |
ADRB1 | GeneProduct | 153 (Entrez Gene) | |
ADRB2 | GeneProduct | 154 (Entrez Gene) | |
ADRB3 | GeneProduct | 155 (Entrez Gene) | |
Acetylcholine | Metabolite | HMDB0000895 (HMDB) | |
CHRM1 | GeneProduct | 1128 (Entrez Gene) | |
CHRM2 | GeneProduct | 1129 (Entrez Gene) | |
CHRM3 | GeneProduct | 1131 (Entrez Gene) | |
CHRM4 | GeneProduct | 1132 (Entrez Gene) | |
CHRM5 | GeneProduct | 1133 (Entrez Gene) | |
DRD1 | GeneProduct | 1812 (Entrez Gene) | |
DRD2 | GeneProduct | 1813 (Entrez Gene) | |
DRD3 | GeneProduct | 1814 (Entrez Gene) | |
DRD4 | GeneProduct | 1815 (Entrez Gene) | |
DRD5 | GeneProduct | 1816 (Entrez Gene) | |
Dopamine | Metabolite | 62-31-7 (CAS) | |
Epinephrine | Metabolite | HMDB0000068 (HMDB) | |
Gi/Go pathway | Pathway | WP35 (WikiPathways) | |
Gq/G11 pathway | Pathway | WP35 (WikiPathways) | |
Gs pathway | Pathway | WP35 (WikiPathways) | |
HRH1 | GeneProduct | 3269 (Entrez Gene) | |
HRH2 | GeneProduct | 3274 (Entrez Gene) | |
HTR1A | GeneProduct | 3350 (Entrez Gene) | |
HTR1B | GeneProduct | 3351 (Entrez Gene) | |
HTR1D | GeneProduct | 3352 (Entrez Gene) | |
HTR1E | GeneProduct | 3354 (Entrez Gene) | |
HTR1F | GeneProduct | 3355 (Entrez Gene) | |
HTR2A | GeneProduct | 3356 (Entrez Gene) | |
HTR2B | GeneProduct | 3357 (Entrez Gene) | |
HTR2C | GeneProduct | 3358 (Entrez Gene) | |
HTR4 | GeneProduct | 3360 (Entrez Gene) | |
HTR5A | GeneProduct | 3361 (Entrez Gene) | |
HTR5B | GeneProduct | 645694 (Entrez Gene) | |
HTR6 | GeneProduct | 3362 (Entrez Gene) | |
HTR7 | GeneProduct | 3363 (Entrez Gene) | |
Histamine | Metabolite | 51-45-6 (CAS) | |
Muscarine | Metabolite | CHEBI:7034 (ChEBI) | |
Norepinephrine | Metabolite | HMDB0000216 (HMDB) | |
Serotonin | Metabolite | 50-67-9 (CAS) |
Annotated Interactions
No annotated interactions