Translation factors (Homo sapiens)
From WikiPathways
Description
Protein synthesis is the ultimate step of gene expression and a key control point for regulation. In particular, it enables cells to rapidly manipulate protein production without new mRNA synthesis, processing, or export. This pathway gives an overview of the translation factors involved in this process.
Proteins on this pathway have targeted assays available via the CPTAC Assay Portal.
Quality Tags
Ontology Terms
Bibliography
- Dever TE; ''Gene-specific regulation by general translation factors.''; Cell, 2002 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
EEF1A1 | GeneProduct | 1915 (Entrez Gene) | |
EEF1A2 | GeneProduct | 1917 (Entrez Gene) | |
EEF1B2 | GeneProduct | 1933 (Entrez Gene) | |
EEF1D | GeneProduct | 1936 (Entrez Gene) | |
EEF1G | GeneProduct | 1937 (Entrez Gene) | |
EEF2 | GeneProduct | 1938 (Entrez Gene) | |
EEF2K | GeneProduct | 29904 (Entrez Gene) | |
EIF1AX | GeneProduct | 1964 (Entrez Gene) | |
EIF1AY | GeneProduct | 9086 (Entrez Gene) | |
EIF2AK1 | GeneProduct | 27102 (Entrez Gene) | |
EIF2AK2 | GeneProduct | 5610 (Entrez Gene) | now E2K2 HUMAN |
EIF2AK3 | GeneProduct | 9451 (Entrez Gene) | |
EIF2B1 | GeneProduct | 1967 (Entrez Gene) | |
EIF2B2 | GeneProduct | 8892 (Entrez Gene) | |
EIF2B3 | GeneProduct | 8891 (Entrez Gene) | |
EIF2B4 | GeneProduct | 8890 (Entrez Gene) | |
EIF2B5 | GeneProduct | 8893 (Entrez Gene) | |
EIF2S1 | GeneProduct | 1965 (Entrez Gene) | |
EIF2S2 | GeneProduct | 8894 (Entrez Gene) | |
EIF2S3 | GeneProduct | 1968 (Entrez Gene) | |
EIF3S10 | GeneProduct | 8661 (Entrez Gene) | |
EIF3S1 | GeneProduct | 8669 (Entrez Gene) | |
EIF3S2 | GeneProduct | 8668 (Entrez Gene) | |
EIF3S3 | GeneProduct | 8667 (Entrez Gene) | |
EIF3S4 | GeneProduct | 8666 (Entrez Gene) | |
EIF3S5 | GeneProduct | 8665 (Entrez Gene) | |
EIF3S6 | GeneProduct | 3646 (Entrez Gene) | |
EIF3S7 | GeneProduct | 8664 (Entrez Gene) | |
EIF3S8 | GeneProduct | 8663 (Entrez Gene) | |
EIF3S9 | GeneProduct | 8662 (Entrez Gene) | |
EIF4A1 | GeneProduct | 1973 (Entrez Gene) | |
EIF4A2 | GeneProduct | 1974 (Entrez Gene) | |
EIF4B | GeneProduct | 1975 (Entrez Gene) | |
EIF4E | GeneProduct | 1977 (Entrez Gene) | |
EIF4EBP1 | GeneProduct | 1978 (Entrez Gene) | |
EIF4EBP2 | GeneProduct | 1979 (Entrez Gene) | |
EIF4EBP3 | GeneProduct | 8637 (Entrez Gene) | |
EIF4G1 | GeneProduct | 1981 (Entrez Gene) | TrEMBL accession number O43177 refers to same protein. |
EIF4G3 | GeneProduct | 8672 (Entrez Gene) | |
EIF5 | GeneProduct | 1983 (Entrez Gene) | |
EIF5A | GeneProduct | 1984 (Entrez Gene) | |
EIF5B | GeneProduct | 9669 (Entrez Gene) | |
ETF1 | GeneProduct | 2107 (Entrez Gene) | |
GSPT2 | GeneProduct | 23708 (Entrez Gene) | |
ITGB4BP | GeneProduct | 3692 (Entrez Gene) | |
KIAA0664 | GeneProduct | 23277 (Entrez Gene) | |
PABPC1 | GeneProduct | 26986 (Entrez Gene) | |
PAIP1 | GeneProduct | 10605 (Entrez Gene) | |
SUI1 | GeneProduct | 10209 (Entrez Gene) | |
WBSCR1 | GeneProduct | 7458 (Entrez Gene) |
Annotated Interactions
No annotated interactions