Regulation of actin cytoskeleton (Rattus norvegicus)
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Lamellipodia
Actin
polymerization
GPCR
Adherens junction
pathway
MAPK Signaling
pathway
RAS
RAS
PI3K
GPCR
+p
Gene Expression
Actin polymerization
stress fiber
RTK
Filipodia
PI3K
Growth Factor (GF)
RTK
stress fiber
Focal adhesion
pathway
Focal complex
assembly
Actin polymerization
Focal adhesion
pathway
GF
Chemotactic factor
Actomyosin
assembly contraction
Chemotatic factor
?
-p
Focal adhesion
assembly
Stabilization
of actin
Acetylcholine
Rock2
Vav1
Fgf20
Csk
Ins1
Chrm5
Pik3r5
PIP2
Arpc5
LOC442775
Pik3r4
Pdgfrb
CDC42
Fgfr1
Nras
Fgf9
Vil1
Pxn
Map2k1
Egf
LPS
Mras
F2r
Gsn
Gng12
Ssh1
Cfl1
Pak3
Ptk2
Pik3c2g
Bdkrb1
Wasf2
Gna12
Actb
Pik3r3
Cd14
PIP2
Mylk
RAC3
Pip5k1c
Pik3r2
Arhgef7
Cfl2
Ssh3
Pik3cg
Itga1
Mapk3
Wasf1
Pik3cb
Rdx
Fgfr4
Pdgfb
F2
Pik3c2a
Mapk4
Git1
Mapk6
Fgf12
Enah
Chrm3
Vcl
Chrm4
Rhoa
Fgf21
Pip4k2b
Mapk1
Fgf3
PIK3CA
Apc
Raf1
Fgf14
Actg1
Pip4k2a
Myh10
Rassf7
Gna13
Sos1
Dock1
Pak2
Baiap2
Braf
Rock1
Pip4k2c
Fgf7
SOS2
Myl3
Pak7
Crk
Pak6
Msn
Map2k2
Arhgef4
Slc9a1
TMSB4X
Ssh2
DIAP3
CYFIP2
Limk1
Pdgfa
Fgf6
Fgf13
Chrm2
Pdgfra
Iqgap1
FGF18
Mos
PIP5KL1
Bdkrb2
Arhgef1
PIP5K1A
RAC1P4
Fn1
PIP3
Pfn1
Actn1
Fgd1
Vcl
Fgf1
Pak4
Actb
Pik3r1
Ins2
Arhgef6
Rras2
Fgf11
Actg1
Rac1
Fgf2
Chrm1
Pfn1
Baiap2
Bradykinin
Kras
WAS
Grlf1
Actg1
Fgf16
Pik3c2b
Bcar1
Fgf15
Pip5k1b
Abi2
Myl1
Pik3c3
Arhgef6
Fgf5
Egfr
Fgf23
Ppp1r12a
Arpc5
Apc2
Ezr
Pik3cd
Nckap1
c3orf10
Pip4k2a
Fgf22
Rras
Rac2
DIAP1
Fgf4
Fgf17
Actb
Fgfr2
Pak1
Fgf10
Fgf8
Fgfr3
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP51(r20783)
with a 90% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
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Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
117008
view
11:21, 16 May 2021
Eweitz
Modified title
109392
view
16:03, 16 March 2020
L Dupuis
Converted interactions to graphical lines
105000
view
04:50, 28 June 2019
Khanspers
removed KEGG comments
72164
view
12:24, 25 October 2013
Egonw
Added missing metabolite IDs.
71785
view
20:32, 17 October 2013
MaintBot
Automated update of data sources
71299
view
16:58, 17 October 2013
MaintBot
Automated update of data sources
69385
view
18:57, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67622
view
11:34, 26 June 2013
Ddigles
Ontology Term : 'cell adhesion signaling pathway' added !
47758
view
05:00, 6 April 2012
Khanspers
updated xref
47757
view
04:58, 6 April 2012
Khanspers
updated xrefs
41701
view
02:37, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34083
view
19:13, 9 December 2009
MaintBot
Automatic update of empty xrefs
32406
view
17:03, 15 August 2009
MaintBot
Fixed text labels
32061
view
13:34, 14 August 2009
MaintBot
Fixed group labels
31436
view
21:04, 13 August 2009
MaintBot
Fixed text labels
31003
view
01:01, 30 July 2009
MaintBot
Converted from Homo sapiens
21415
view
11:31, 14 November 2008
MaintBot
[[Pathway:Rattus norvegicus:Regulation of Actin Cytoskeleton KEGG]] moved to [[Pathway:WP351]]: Moved to stable identifier
8358
view
13:46, 7 January 2008
MaintBot
[[Pathway:Rat:Regulation of Actin Cytoskeleton KEGG]] moved to [[Pathway:Rattus norvegicus:Regulation of Actin Cytoskeleton KEGG]]: Renaming species
7797
view
16:18, 18 December 2007
MaintBot
fixed category names
7291
view
12:41, 4 November 2007
MaintBot
Added categories to GPML
6590
view
22:20, 22 May 2007
169.230.77.174
gpml file for [[Rat:Regulation_of_Actin_Cytoskeleton_KEGG]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Abi2
GeneProduct
286928 (Entrez Gene)
Acetylcholine
Metabolite
CHEBI:15355 (ChEBI)
Actb
GeneProduct
81822 (Entrez Gene)
Actg1
GeneProduct
287876 (Entrez Gene)
Actn1
GeneProduct
81634 (Entrez Gene)
Apc2
GeneProduct
299611 (Entrez Gene)
Apc
GeneProduct
24205 (Entrez Gene)
Arhgef1
GeneProduct
60323 (Entrez Gene)
Arhgef4
GeneProduct
301334 (Entrez Gene)
Arhgef6
GeneProduct
363509 (Entrez Gene)
Arhgef7
GeneProduct
114559 (Entrez Gene)
Arpc5
GeneProduct
360854 (Entrez Gene)
Baiap2
GeneProduct
117542 (Entrez Gene)
Bcar1
GeneProduct
25414 (Entrez Gene)
Bdkrb1
GeneProduct
81509 (Entrez Gene)
Bdkrb2
GeneProduct
25245 (Entrez Gene)
Bradykinin
Metabolite
CHEBI:3165 (ChEBI)
Braf
GeneProduct
114486 (Entrez Gene)
CDC42
GeneProduct
64465 (Entrez Gene)
CYFIP2
GeneProduct
303073 (Entrez Gene)
Cd14
GeneProduct
60350 (Entrez Gene)
Cfl1
GeneProduct
29271 (Entrez Gene)
Cfl2
GeneProduct
366624 (Entrez Gene)
Chrm1
GeneProduct
25229 (Entrez Gene)
Chrm2
GeneProduct
81645 (Entrez Gene)
Chrm3
GeneProduct
24260 (Entrez Gene)
Chrm4
GeneProduct
25111 (Entrez Gene)
Chrm5
GeneProduct
53949 (Entrez Gene)
Crk
GeneProduct
54245 (Entrez Gene)
Csk
GeneProduct
315707 (Entrez Gene)
DIAP1
GeneProduct
DIAP3
GeneProduct
Dock1
GeneProduct
309081 (Entrez Gene)
Egf
GeneProduct
25313 (Entrez Gene)
Egfr
GeneProduct
24329 (Entrez Gene)
Enah
GeneProduct
360891 (Entrez Gene)
Ezr
GeneProduct
54319 (Entrez Gene)
F2
GeneProduct
29251 (Entrez Gene)
F2r
GeneProduct
25439 (Entrez Gene)
FGF18
GeneProduct
29369 (Entrez Gene)
Fgd1
GeneProduct
363460 (Entrez Gene)
Fgf10
GeneProduct
25443 (Entrez Gene)
Fgf11
GeneProduct
170632 (Entrez Gene)
Fgf12
GeneProduct
170630 (Entrez Gene)
Fgf1
GeneProduct
25317 (Entrez Gene)
Fgf13
GeneProduct
84488 (Entrez Gene)
Fgf14
GeneProduct
63851 (Entrez Gene)
Fgf15
GeneProduct
170582 (Entrez Gene)
Fgf16
GeneProduct
60464 (Entrez Gene)
Fgf17
GeneProduct
29368 (Entrez Gene)
Fgf20
GeneProduct
66017 (Entrez Gene)
Fgf21
GeneProduct
170580 (Entrez Gene)
Fgf22
GeneProduct
170579 (Entrez Gene)
Fgf23
GeneProduct
170583 (Entrez Gene)
Fgf2
GeneProduct
54250 (Entrez Gene)
Fgf3
GeneProduct
170633 (Entrez Gene)
Fgf4
GeneProduct
116499 (Entrez Gene)
Fgf5
GeneProduct
60662 (Entrez Gene)
Fgf6
GeneProduct
170700 (Entrez Gene)
Fgf7
GeneProduct
29348 (Entrez Gene)
Fgf8
GeneProduct
29349 (Entrez Gene)
Fgf9
GeneProduct
25444 (Entrez Gene)
Fgfr1
GeneProduct
79114 (Entrez Gene)
Fgfr2
GeneProduct
25022 (Entrez Gene)
Fgfr3
GeneProduct
84489 (Entrez Gene)
Fgfr4
GeneProduct
25114 (Entrez Gene)
Fn1
GeneProduct
25661 (Entrez Gene)
Git1
GeneProduct
83709 (Entrez Gene)
Gna12
GeneProduct
81663 (Entrez Gene)
Gna13
GeneProduct
303634 (Entrez Gene)
Gng12
GeneProduct
114120 (Entrez Gene)
Grlf1
GeneProduct
306400 (Entrez Gene)
Gsn
GeneProduct
296654 (Entrez Gene)
Ins1
GeneProduct
24505 (Entrez Gene)
Ins2
GeneProduct
24506 (Entrez Gene)
Iqgap1
GeneProduct
361598 (Entrez Gene)
Itga1
GeneProduct
25118 (Entrez Gene)
Kras
GeneProduct
24525 (Entrez Gene)
LOC442775
GeneProduct
LPS
Metabolite
C00338 (KEGG Compound)
Limk1
GeneProduct
65172 (Entrez Gene)
Map2k1
GeneProduct
170851 (Entrez Gene)
Map2k2
GeneProduct
58960 (Entrez Gene)
Mapk1
GeneProduct
116590 (Entrez Gene)
Mapk3
GeneProduct
50689 (Entrez Gene)
Mapk4
GeneProduct
54268 (Entrez Gene)
Mapk6
GeneProduct
58840 (Entrez Gene)
Mos
GeneProduct
24559 (Entrez Gene)
Mras
GeneProduct
25482 (Entrez Gene)
Msn
GeneProduct
81521 (Entrez Gene)
Myh10
GeneProduct
79433 (Entrez Gene)
Myl1
GeneProduct
56781 (Entrez Gene)
Myl3
GeneProduct
24585 (Entrez Gene)
Mylk
GeneProduct
288057 (Entrez Gene)
Nckap1
GeneProduct
58823 (Entrez Gene)
Nras
GeneProduct
24605 (Entrez Gene)
PIK3CA
GeneProduct
170911 (Entrez Gene)
PIP2
Metabolite
C04637 (KEGG Compound)
PIP3
Metabolite
C05981 (KEGG Compound)
PIP5K1A
GeneProduct
365865 (Entrez Gene)
PIP5KL1
GeneProduct
Pak1
GeneProduct
29431 (Entrez Gene)
Pak2
GeneProduct
29432 (Entrez Gene)
Pak3
GeneProduct
29433 (Entrez Gene)
Pak4
GeneProduct
292756 (Entrez Gene)
Pak6
GeneProduct
296078 (Entrez Gene)
Pak7
GeneProduct
311450 (Entrez Gene)
Pdgfa
GeneProduct
25266 (Entrez Gene)
Pdgfb
GeneProduct
24628 (Entrez Gene)
Pdgfra
GeneProduct
25267 (Entrez Gene)
Pdgfrb
GeneProduct
24629 (Entrez Gene)
Pfn1
GeneProduct
64303 (Entrez Gene)
Pik3c2a
GeneProduct
361632 (Entrez Gene)
Pik3c2b
GeneProduct
289021 (Entrez Gene)
Pik3c2g
GeneProduct
116720 (Entrez Gene)
Pik3c3
GeneProduct
65052 (Entrez Gene)
Pik3cb
GeneProduct
85243 (Entrez Gene)
Pik3cd
GeneProduct
366508 (Entrez Gene)
Pik3cg
GeneProduct
298947 (Entrez Gene)
Pik3r1
GeneProduct
25513 (Entrez Gene)
Pik3r2
GeneProduct
29741 (Entrez Gene)
Pik3r3
GeneProduct
60664 (Entrez Gene)
Pik3r4
GeneProduct
363131 (Entrez Gene)
Pik3r5
GeneProduct
497931 (Entrez Gene)
Pip4k2a
GeneProduct
116723 (Entrez Gene)
Pip4k2b
GeneProduct
89812 (Entrez Gene)
Pip4k2c
GeneProduct
140607 (Entrez Gene)
Pip5k1b
GeneProduct
309419 (Entrez Gene)
Pip5k1c
GeneProduct
314641 (Entrez Gene)
Ppp1r12a
GeneProduct
116670 (Entrez Gene)
Ptk2
GeneProduct
25614 (Entrez Gene)
Pxn
GeneProduct
360820 (Entrez Gene)
RAC1P4
GeneProduct
RAC3
GeneProduct
Rac1
GeneProduct
363875 (Entrez Gene)
Rac2
GeneProduct
366957 (Entrez Gene)
Raf1
GeneProduct
24703 (Entrez Gene)
Rassf7
GeneProduct
293623 (Entrez Gene)
Rdx
GeneProduct
315655 (Entrez Gene)
Rhoa
GeneProduct
117273 (Entrez Gene)
Rock1
GeneProduct
81762 (Entrez Gene)
Rock2
GeneProduct
25537 (Entrez Gene)
Rras2
GeneProduct
365355 (Entrez Gene)
Rras
GeneProduct
361568 (Entrez Gene)
SOS2
GeneProduct
85384 (Entrez Gene)
Slc9a1
GeneProduct
24782 (Entrez Gene)
Sos1
GeneProduct
313845 (Entrez Gene)
Ssh1
GeneProduct
304580 (Entrez Gene)
Ssh2
GeneProduct
303342 (Entrez Gene)
Ssh3
GeneProduct
365396 (Entrez Gene)
TMSB4X
GeneProduct
81814 (Entrez Gene)
Vav1
GeneProduct
25156 (Entrez Gene)
Vcl
GeneProduct
305679 (Entrez Gene)
Vil1
GeneProduct
316521 (Entrez Gene)
WAS
GeneProduct
317371 (Entrez Gene)
Wasf1
GeneProduct
294568 (Entrez Gene)
Wasf2
GeneProduct
313024 (Entrez Gene)
c3orf10
GeneProduct
Annotated Interactions
No annotated interactions
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Bibliography
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History
External references
DataNodes
Annotated Interactions
No annotated interactions