Toll-like receptor signaling pathway (Bos taurus)

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Toll-like receptors (TLRs) are a critical part of the innate immune response, and are expressed on macrophages and dendritic cells. TLRs are pattern-recognition receptors, and recognize molecules derived from microbes. Once activated, TLRs result in activation of innate immunity by inducing production of proinflammatory cytokines and upregulation of costimulatory molecules

HomologyConvert 

This pathway was inferred from Homo sapiens pathway WP75(72133) with a 95.0% conversion rate.