Apoptosis modulation by HSP70 (Bos taurus)

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Bibliography

1. Gurbuxani S, Schmitt E, Cande C, Parcellier A, Hammann A, Daugas E, Kouranti I, Spahr C, Pance A, Kroemer G, Garrido C; ''Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor.''; Oncogene, 2003 PubMed Europe PMC Scholia
2. Orsini F, Migliaccio E, Moroni M, Contursi C, Raker VA, Piccini D, Martin-Padura I, Pelliccia G, Trinei M, Bono M, Puri C, Tacchetti C, Ferrini M, Mannucci R, Nicoletti I, Lanfrancone L, Giorgio M, Pelicci PG; ''The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
3. Saleh A, Srinivasula SM, Balkir L, Robbins PD, Alnemri ES; ''Negative regulation of the Apaf-1 apoptosome by Hsp70.''; Nat Cell Biol, 2000 PubMed Europe PMC Scholia
4. Garrido C, Schmitt E, Candé C, Vahsen N, Parcellier A, Kroemer G; ''HSP27 and HSP70: potentially oncogenic apoptosis inhibitors.''; Cell Cycle, 2003 PubMed Europe PMC Scholia
5. Gabai VL, Meriin AB, Yaglom JA, Volloch VZ, Sherman MY; ''Role of Hsp70 in regulation of stress-kinase JNK: implications in apoptosis and aging.''; FEBS Lett, 1998 PubMed Europe PMC Scholia
6. Mosser DD, Caron AW, Bourget L, Meriin AB, Sherman MY, Morimoto RI, Massie B; ''The chaperone function of hsp70 is required for protection against stress-induced apoptosis.''; Mol Cell Biol, 2000 PubMed Europe PMC Scholia
7. Jäättelä M, Wissing D, Kokholm K, Kallunki T, Egeblad M; ''Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.''; EMBO J, 1998 PubMed Europe PMC Scholia
8. Schett G, Steiner CW, Gröger M, Winkler S, Graninger W, Smolen J, Xu Q, Steiner G; ''Activation of Fas inhibits heat-induced activation of HSF1 and up-regulation of hsp70.''; FASEB J, 1999 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
AIFM1	GeneProduct	ENSBTAG00000006838 (Ensembl)	Apoptosis Inducing Factor HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9131
APAF1	GeneProduct	ENSBTAG00000021661 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:317
Apoptosis	Pathway	WP254 (WikiPathways)
BID2	GeneProduct	ENSBTAG00000013988 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:637
CASP2	GeneProduct	ENSBTAG00000018159 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:835
CASP3	GeneProduct	ENSBTAG00000015874 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:836
CASP6	GeneProduct	ENSBTAG00000012537 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:839
CASP7	GeneProduct	ENSBTAG00000006615 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:840
CASP8	GeneProduct	ENSBTAG00000015718 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:841
CASP9	GeneProduct	ENSBTAG00000002472 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:842
CYCS	GeneProduct	ENSBTAG00000022613 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:54205
FADD	GeneProduct	ENSBTAG00000018274 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8772
FAS	GeneProduct	ENSBTAG00000010785 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:355
FASLG	GeneProduct	ENSBTAG00000032808 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000117560
HSPA1A	GeneProduct		HomologyConvert: Multiple homologues found: En:ENSBTAG00000025441;En:ENSBTAG00000025441;
MAP3K1	GeneProduct	ENSBTAG00000013790 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4214
MAPK10	GeneProduct	ENSBTAG00000020048 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5602
NF-kB Pathway	Pathway
NFKB1	GeneProduct	ENSBTAG00000020270 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4790
RIPK1	GeneProduct	ENSBTAG00000006378 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8737
TNF-alpha	GeneProduct
TNFRSF1A	GeneProduct	ENSBTAG00000004211 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7132

Annotated Interactions