Small ligand GPCRs (Canis familiaris)

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ProstanoidsGq/G11 PathwayGi PathwayGq/G11 PathwayMelatoninCannabinoidPlatelet ActivatingLysophosphatidicAcidS1PR4PTGER3Mel-1CMTNR1APTGER4PTGER1CNR2S1PR2LPAR1PTGER2PTGFRCNR1PTGDRPTGIRS1PR3MTNR1BPTAFRTBXA2RS1PR1


Description

G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: Wikipedia These small ligand receptors are part of the Rhodopsin-like family of GPCRs. Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP247(r21199) with a 89% conversion rate.

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Bibliography

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History

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CompareRevisionActionTimeUserComment
117461view10:55, 21 May 2021EweitzModified title
96078view18:45, 15 February 2018KhanspersModified description
87673view08:55, 25 July 2016LindarieswijkOntology Term : 'G protein mediated signaling pathway' added !
71474view19:18, 17 October 2013MaintBotAutomated update of data sources
68564view22:49, 5 July 2013MaintBotUpdated to 2013 gpml schema
62722view03:17, 2 May 2013MaintBotUpdated UniProt data source
40722view21:52, 1 March 2011MaintBotRemoved redundant pathway information and comments
34001view18:38, 9 December 2009MaintBotAutomatic update of empty xrefs
32538view13:02, 17 August 2009MaintBotFixed text labels
32224view12:47, 15 August 2009MaintBotFixed text labels
31721view11:55, 14 August 2009MaintBotFixed group labels
31236view19:46, 13 August 2009MaintBotFixed text labels
30658view22:36, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CNR1GeneProduct481913 (Entrez Gene)
CNR2GeneProduct612289 (Entrez Gene)
LPAR1GeneProduct474800 (Entrez Gene)
MTNR1AGeneProduct482904 (Entrez Gene)
MTNR1BGeneProduct607818 (Entrez Gene)
Mel-1CGeneProduct
PTAFRGeneProduct487336 (Entrez Gene)
PTGDRGeneProduct610845 (Entrez Gene)
PTGER1GeneProduct610774 (Entrez Gene)
PTGER2GeneProduct403797 (Entrez Gene)
PTGER3GeneProduct403430 (Entrez Gene)
PTGER4GeneProduct403589 (Entrez Gene)
PTGFRGeneProduct479981 (Entrez Gene)
PTGIRGeneProduct484429 (Entrez Gene)
S1PR1GeneProduct490138 (Entrez Gene)
S1PR2GeneProduct484959 (Entrez Gene)
S1PR3GeneProduct484199 (Entrez Gene)
S1PR4GeneProduct612082 (Entrez Gene)
TBXA2RGeneProduct485056 (Entrez Gene)

Annotated Interactions

No annotated interactions
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