IL-6 signaling pathway (Canis familiaris)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none AutophosphorylationEarly EndosomesInhibitionTranslocationCytoplasmCY->NUPhosphorylationDephosphorylationAcetylationCY->NUCY->NUDDDDDDCY->ENCY->NUCY->NUDDDDDLigandReceptorMolecule in the pathwayCY->NUActivationComplex formationGene SymbolDDAccession Number: NetPath 18Proteins in a complex interactionEnzyme complex(Protein-Protein interaction)DReactions through unknown mechanisms/moleculesDeacetylationGlycosylationMethylationDemethylationPalmitoylationProteolytic cleavageSumoylationDesumoylationUbiquitinationDeubiquitinationRecruitmentControlCYExtracellularECENEndosomeEREndoplasmic reticulumGOGolgi apparatusMTMitochondrionNUNucleusPMPlasma membraneMolecular associationIL6IL6RIL6RIL6STIL6STFESTECBTKJAK2PTPN11JAK1TYK2SHC1GRB2STAT3SOS1VAV1MAPK1GAB1PIK3R1PIK3R2STAT1STAT1STAT1STAT3STAT1STAT3STAT3STAT3MAPK14MAPK14SGK1SGK1NFKB1NFKB1NLKHRASNCOA1CREBBPRAC1CDK9DAXXARLOC487309PRKCDPTK2BGAB2MAP2K4LOC480438SOCS3FOSJUNHNF1ACEBPBERBB2ERBB3HCKLYNCEBPBRAF1CASP3CASP9PPP2CAPPP2CBPPP2R1APPP2R1BPPP2R2APPP2R2BPPP2R2CPPP2R3APPP2R3BPPP2R4PPP2R5APPP2R5BPPP2R5CPPP2R5DPPP2R5EEP300MAP2K6CDK5MAPTRPS6KA2MAPK3FGRPLCG1MAP3K4RB1AKT1BADGSK3BFOXO1MAP2K1MAP2K2EIF4EEIF2AMAPK8PTK2PXNFOXO3AFOXO4INPP5DINPPL1RPS6KB1EIF4EBP1BMXFYNCD40STAT3STAT5ASTAT5BSTAT3STAT3MAPKAPK2MAP3K7MAP3K7HSPB1IL6CDK5R1Name: IL-6 signaling pathwayOrganism: Canis familiaris


Description

No description

Comments

GenMAPP notes 
NetPath 18 - IL-6 signaling pathway. NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP364(r28142) with a 91% conversion rate.

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Quality Tags

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Homology Converted

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
118000
Homology Converted
view11:25, 23 May 2021EweitzModified title
86937view13:07, 15 July 2016MkutmonOntology Term : 'interleukin-6 signaling pathway' added !
68562view22:47, 5 July 2013MaintBotUpdated to 2013 gpml schema
40720view21:52, 1 March 2011MaintBotRemoved redundant pathway information and comments
33999view18:38, 9 December 2009MaintBotAutomatic update of empty xrefs
32542view13:03, 17 August 2009MaintBotFixed text labels
31240view19:48, 13 August 2009MaintBotFixed text labels
30663view22:37, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
Name  â†“Type  â†“Database reference  â†“Comment  â†“
AKT1GeneProduct490878 (Entrez Gene)
ARGeneProduct403588 (Entrez Gene)
BADGeneProduct483763 (Entrez Gene)
BMXGeneProduct491750 (Entrez Gene)
BTKGeneProduct492019 (Entrez Gene)
CASP3GeneProduct403567 (Entrez Gene)
CASP9GeneProduct487432 (Entrez Gene)
CD40GeneProduct403469 (Entrez Gene)
CDK5GeneProduct475537 (Entrez Gene)
CDK5R1GeneProduct491154 (Entrez Gene)
CDK9GeneProduct491325 (Entrez Gene)
CEBPBGeneProduct
CREBBPGeneProduct479866 (Entrez Gene)
DAXXGeneProduct474873 (Entrez Gene)
EIF2AGeneProduct477112 (Entrez Gene)
EIF4EGeneProduct487870 (Entrez Gene)
EIF4EBP1GeneProduct475590 (Entrez Gene)
EP300GeneProduct
ERBB2GeneProduct403883 (Entrez Gene)
ERBB3GeneProduct481105 (Entrez Gene)
FESGeneProduct609483 (Entrez Gene)
FGRGeneProduct487341 (Entrez Gene)
FOSGeneProduct490792 (Entrez Gene)
FOXO1GeneProduct477295 (Entrez Gene)
FOXO3AGeneProduct
FOXO4GeneProduct491946 (Entrez Gene)
FYNGeneProduct475032 (Entrez Gene)
GAB1GeneProduct483808 (Entrez Gene)
GAB2GeneProduct485167 (Entrez Gene)
GRB2GeneProduct483312 (Entrez Gene)
GSK3BGeneProduct478575 (Entrez Gene)
HCKGeneProduct485828 (Entrez Gene)
HNF1AGeneProduct486303 (Entrez Gene)
HRASGeneProduct
HSPB1GeneProduct403979 (Entrez Gene)
IL6GeneProduct403985 (Entrez Gene)
IL6RGeneProduct612271 (Entrez Gene)
IL6STGeneProduct403545 (Entrez Gene)
INPP5DGeneProduct
INPPL1GeneProduct485209 (Entrez Gene)
JAK1GeneProduct442952 (Entrez Gene)
JAK2GeneProduct484185 (Entrez Gene)
JUNGeneProduct609429 (Entrez Gene)
LOC480438GeneProduct480438 (Entrez Gene)
LOC487309GeneProduct487309 (Entrez Gene)
LYNGeneProduct477886 (Entrez Gene)
MAP2K1GeneProduct478347 (Entrez Gene)
MAP2K2GeneProduct611939 (Entrez Gene)
MAP2K4GeneProduct489508 (Entrez Gene)
MAP2K6GeneProduct480454 (Entrez Gene)
MAP3K4GeneProduct476262 (Entrez Gene)
MAP3K7GeneProduct474996 (Entrez Gene)
MAPK14GeneProduct403856 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
MAPK8GeneProduct477746 (Entrez Gene)
MAPKAPK2GeneProduct490263 (Entrez Gene)
MAPTGeneProduct480488 (Entrez Gene)
NCOA1GeneProduct475684 (Entrez Gene)
NFKB1GeneProduct442859 (Entrez Gene)
NLKGeneProduct491160 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PIK3R2GeneProduct609956 (Entrez Gene)
PLCG1GeneProduct485874 (Entrez Gene)
PPP2CAGeneProduct403608 (Entrez Gene)
PPP2CBGeneProduct482873 (Entrez Gene)
PPP2R1AGeneProduct484335 (Entrez Gene)
PPP2R1BGeneProduct479444 (Entrez Gene)
PPP2R2AGeneProduct477374 (Entrez Gene)
PPP2R2BGeneProduct478053 (Entrez Gene)
PPP2R2CGeneProduct610262 (Entrez Gene)
PPP2R3AGeneProduct485672 (Entrez Gene)
PPP2R3BGeneProduct607103 (Entrez Gene)
PPP2R4GeneProduct491303 (Entrez Gene)
PPP2R5AGeneProduct490280 (Entrez Gene)
PPP2R5BGeneProduct483755 (Entrez Gene)
PPP2R5CGeneProduct480436 (Entrez Gene)
PPP2R5DGeneProduct481806 (Entrez Gene)
PPP2R5EGeneProduct480349 (Entrez Gene)
PRKCDGeneProduct494005 (Entrez Gene)
PTK2GeneProduct475108 (Entrez Gene)
PTK2BGeneProduct486102 (Entrez Gene)
PTPN11GeneProduct477488 (Entrez Gene)
PXNGeneProduct486299 (Entrez Gene)
RAC1GeneProduct403955 (Entrez Gene)
RAF1GeneProduct484648 (Entrez Gene)
RB1GeneProduct476915 (Entrez Gene)
RPS6KA2GeneProduct612448 (Entrez Gene)
RPS6KB1GeneProduct480580 (Entrez Gene)
SGK1GeneProduct403647 (Entrez Gene)
SHC1GeneProduct490439 (Entrez Gene)
SOCS3GeneProduct442949 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene)
STAT1GeneProduct488449 (Entrez Gene)
STAT3GeneProduct490967 (Entrez Gene)
STAT5AGeneProduct490968 (Entrez Gene)
STAT5BGeneProduct490969 (Entrez Gene)
TECGeneProduct482140 (Entrez Gene)
TYK2GeneProduct476714 (Entrez Gene)
VAV1GeneProduct485016 (Entrez Gene)

Annotated Interactions

No annotated interactions
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