Prostaglandin synthesis and regulation (Canis familiaris)
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Inactive Metabolites
prolactin
release
Cytoplasm
Cortisone
Gq signaling
pathway
PG Synthases
Cell Membrane
Phospholipids
PTGFR
Prostaglandin H2
PTGS1
EDNRB
PTGER4
PTGER1
ANXA4
HSD11B1
PTGER2
PTGS2
PLA2G4A
ANXA6
PGI2
PTGDR
PTGER3
HSD11B2
ANXA8
SCGB1A1
Arachidonic Acid
PGF2a
TXA2
ANXA1
Cortisol
Calcium
ANXA5
ANXA3
PTGDS
HPGD
Cortisol
PGE2
EDN1
Progesterone
PTGIS
ANXA2
Calcium
PTGIR
PRL
EDNRA
TBXAS1
S100A6
LOC478365
PGF2a
S100A10
Description
No description
Comments
GenMAPP notes
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks
See note for more details
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP98(r20887)
with a 80% conversion rate.
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Bibliography
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History
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Compare
Revision
Action
Time
User
Comment
118056
view
10:36, 24 May 2021
Eweitz
Modified title
106037
view
11:56, 16 August 2019
MaintBot
HMDB identifier normalization
87601
view
08:53, 25 July 2016
Lindarieswijk
Ontology Term : 'prostaglandin biosynthetic pathway' added !
87600
view
08:53, 25 July 2016
Lindarieswijk
Ontology Term : 'prostaglandin signaling pathway' added !
71459
view
19:17, 17 October 2013
MaintBot
Automated update of data sources
68524
view
22:08, 5 July 2013
MaintBot
Updated to 2013 gpml schema
40678
view
21:49, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33968
view
18:27, 9 December 2009
MaintBot
Automatic update of empty xrefs
32549
view
13:05, 17 August 2009
MaintBot
Fixed text labels
32231
view
12:49, 15 August 2009
MaintBot
Fixed text labels
31737
view
11:59, 14 August 2009
MaintBot
Fixed group labels
31247
view
19:50, 13 August 2009
MaintBot
Fixed text labels
30680
view
22:43, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ANXA1
GeneProduct
476322 (Entrez Gene)
ANXA2
GeneProduct
403435 (Entrez Gene)
ANXA3
GeneProduct
478447 (Entrez Gene)
ANXA4
GeneProduct
606756 (Entrez Gene)
ANXA5
GeneProduct
476094 (Entrez Gene)
ANXA6
GeneProduct
479325 (Entrez Gene)
ANXA8
GeneProduct
Arachidonic Acid
Metabolite
Calcium
Metabolite
HMDB0000464 (HMDB)
Cortisol
Metabolite
EDN1
GeneProduct
403424 (Entrez Gene)
PMID: 1474344
EDNRA
GeneProduct
450187 (Entrez Gene)
EDNRB
GeneProduct
403862 (Entrez Gene)
HPGD
GeneProduct
486073 (Entrez Gene)
HSD11B1
GeneProduct
449023 (Entrez Gene)
HSD11B2
GeneProduct
489758 (Entrez Gene)
LOC478365
GeneProduct
478365 (Entrez Gene)
PGE2
Metabolite
HMDB0003175 (HMDB)
PGF2a
Metabolite
HMDB0001139 (HMDB)
PGI2
Metabolite
HMDB0001335 (HMDB)
PLA2G4A
GeneProduct
480048 (Entrez Gene)
PRL
GeneProduct
488241 (Entrez Gene)
PTGDR
GeneProduct
610845 (Entrez Gene)
PTGDS
GeneProduct
403740 (Entrez Gene)
PTGER1
GeneProduct
610774 (Entrez Gene)
PTGER2
GeneProduct
403797 (Entrez Gene)
PTGER3
GeneProduct
403430 (Entrez Gene)
PTGER4
GeneProduct
403589 (Entrez Gene)
PTGFR
GeneProduct
479981 (Entrez Gene)
PTGIR
GeneProduct
484429 (Entrez Gene)
PTGIS
GeneProduct
485919 (Entrez Gene)
PTGS1
GeneProduct
403544 (Entrez Gene)
PTGS2
GeneProduct
442942 (Entrez Gene)
Progesterone
Metabolite
Prostaglandin H2
Metabolite
S100A10
GeneProduct
475851 (Entrez Gene)
PMID: 12962548 relationship with Annexin 2
S100A6
GeneProduct
480143 (Entrez Gene)
SCGB1A1
GeneProduct
476060 (Entrez Gene)
PMID: 7615804, PMID: 3292559
TBXAS1
GeneProduct
482771 (Entrez Gene)
TXA2
Metabolite
HMDB0001452 (HMDB)
Annotated Interactions
No annotated interactions
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External references
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Annotated Interactions
No annotated interactions