Cytokines and inflammatory response (Canis familiaris)
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1
Eos
Tc
Eos
T-helper
Endothelial Cells
Plasma Cell
Lymphocyte Activated
Killer Cells (LAK)
antigen
Eos
Hematopoietic Stem Cell
MHC II
Neutrophil
Fibroblasts
T-helper
B Cell
antibodies
Mast Cell
NK cell
B Cell
Tc
B Cell
Hematopoiesis
Hypothalamus
(fever)
Macrophage
Clonal expansion of T cells
Th
TCR
Th
B Cell
Th
Tc
IL4
IL2
CSF3
IFNG
IL1B
IL1A
IL2
IFNB1
IL11
IL6
CSF2
IL10
Inflammatory Response
IL3
TNF
IFN1@
IL1B
IL5
CSF2
CSF1
IFN1@
IL4
IL1B
IL1A
TRB
IL2
TNF
IL4
IFNG
IL10
TGFB1
IL12
IL12B
IFNG
TNF
TGFB1
IL1B
IL10
TRA
IL15
IL6
IL4
IL4
TNF
DLA-DRA1
IL13
TGFB1
IL6
PDGFA
IL1A
TNF
IL1B
CXCL1
TNF
IL10
IL15
IL2
IL5
IL3
IL3
IL3
IL1A
CXCL2
IL13
IL15
DLA-DRB1
TNF
IL6
IL6
CD4
IL7
IL1A
IL2
IL2
IL12B
IL2
Description
See BioCarta version:
http://www.biocarta.com/pathfiles/h_inflamPathway.asp
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP530(r21794)
with a 81% conversion rate.
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Kataoka T; ''Chemical biology of inflammatory cytokine signaling.''; J Antibiot (Tokyo), 2009
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
122663
view
05:36, 28 April 2022
Egonw
Made a pathway clickable
117443
view
10:52, 21 May 2021
Eweitz
Modified title
86862
view
07:30, 14 July 2016
Mkutmon
Ontology Term : 'inflammatory response pathway' added !
86861
view
07:30, 14 July 2016
Mkutmon
Ontology Term : 'PW:0000025' removed !
68531
view
22:16, 5 July 2013
MaintBot
Updated to 2013 gpml schema
67128
view
10:10, 26 June 2013
Christine Chichester
Ontology Term : 'inflammatory response pathway' added !
40687
view
21:50, 1 March 2011
MaintBot
Removed redundant pathway information and comments
38709
view
19:30, 23 September 2010
AlexanderPico
38657
view
12:58, 23 September 2010
FerryJagers
fixed database @ linked pathway
38650
view
12:38, 23 September 2010
FerryJagers
Linked Pathway
35253
view
20:01, 11 February 2010
Thomas
added literature
33973
view
18:29, 9 December 2009
MaintBot
Automatic update of empty xrefs
32550
view
13:06, 17 August 2009
MaintBot
Fixed text labels
32232
view
12:50, 15 August 2009
MaintBot
Fixed text labels
31739
view
12:00, 14 August 2009
MaintBot
Fixed group labels
31248
view
19:51, 13 August 2009
MaintBot
Fixed text labels
30682
view
22:44, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Inflammatory Response
Pathway
WP1156 (WikiPathways)
CD4
GeneProduct
403931 (Entrez Gene)
CSF1
GeneProduct
611795 (Entrez Gene)
CSF2
GeneProduct
403923 (Entrez Gene)
CSF3
GeneProduct
608246 (Entrez Gene)
CXCL1
GeneProduct
CXCL2
GeneProduct
DLA-DRA1
GeneProduct
481731 (Entrez Gene)
DLA-DRB1
GeneProduct
474860 (Entrez Gene)
IFN1@
GeneProduct
IFNB1
GeneProduct
481558 (Entrez Gene)
IFNG
GeneProduct
403801 (Entrez Gene)
IL10
GeneProduct
403628 (Entrez Gene)
IL11
GeneProduct
611309 (Entrez Gene)
IL12
GeneProduct
IL12B
GeneProduct
403976 (Entrez Gene)
IL13
GeneProduct
442990 (Entrez Gene)
IL15
GeneProduct
403584 (Entrez Gene)
IL1A
GeneProduct
403782 (Entrez Gene)
IL1B
GeneProduct
403974 (Entrez Gene)
IL2
GeneProduct
403989 (Entrez Gene)
IL3
GeneProduct
481497 (Entrez Gene)
IL4
GeneProduct
403785 (Entrez Gene)
IL5
GeneProduct
403790 (Entrez Gene)
IL6
GeneProduct
403985 (Entrez Gene)
IL7
GeneProduct
751768 (Entrez Gene)
PDGFA
GeneProduct
491597 (Entrez Gene)
TGFB1
GeneProduct
403998 (Entrez Gene)
TNF
GeneProduct
403922 (Entrez Gene)
TRA
GeneProduct
TRB
GeneProduct
Annotated Interactions
No annotated interactions
Views
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Discussion
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Bibliography
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External references
DataNodes
Annotated Interactions
No annotated interactions