Metapathway biotransformation (Canis familiaris)

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Cytochrome P450ReductionHydrolysisMethylationGlutathione peroxidasesGlutathione reductaseGlutathione conjugationSulfotransferasesAldo-keto reductasesSulfationAmino acid conjugationGlutathione transferasesFlavin monooxygenasesAcetylationGlucuronosyltransferasesAmino acid acyl transferasesN-acetyltransferasesGlutathione synthetaseElectrophilesOxidationMethyltransferasesEpoxide hydrolasesGlucuronidationNucleophilesAKR1C4UGT2A2CYP51A1CHST12CHST1Q9TRV2_CANFACYP4F8Substrate-OHAKR1C2SulfotransferaseCHST3GSTA4Substrate-AaSULT2A1NAT11CYP2A13GSTO2Substrate=OUGT2A1FMO1_CANFAGAL3ST3CYP26C1SULT4A1GPX3Substrate-SHKCNAB2GSTT2BGSTM5Substrate-CH3UGT2B28AKR1B10CYP2U1CP2BB_CANFANAT5NAT14GSTT2GPX1AKR1B1CYP11A1MethyltransferaseCP1A2_CANFAGPX4UGT2B4GSRHS2ST1NAT8LSULT1E1INMTMGST2AKR1D1NNMTQ2VB21_CANFACYP7A1NAT10UGT1A8MGST3CP1A1_CANFACP2E1_CANFAN-acetyltransferaseHS3ST6CYP3A4Glutathione transferaseSULT2B1CHST10CYP8B1GSTM1GSTM2NAT2UGT1A4FMO3_CANFACHST8Q2VB21_CANFAGSTO1CYP27C1CYP1B1CYP2J2UGT2B17UGT2A3CYP27B1NAT9Q3HTU0_CANFAAKR7A2CHST4GAL3ST2CYP2C18CYP2A7Substrate-AcGSTM3AKR7A3FMO2NAT13GLYATL1Q2VB21_CANFAGLYATSULT1C4GAL3ST1Substrate-SO3HCYP17A1SULT1C2GLYATL2CYP7B1Q70DT1_CANFANAT8SULT1C4UGT1A9ST1A1_CANFAGSTK1Amino acid acyltransferaseNDST1HS3ST2AKR1C1TPMT_CANFAGPX2UGT1A1CYP4F12Xenobiotic substrateFMO5Q2VB21_CANFAST1A1_CANFAFlavin monooxygenaseGSTZ1CYP2R1CHST6GSTP1GSTT1CYP39A1Q3HTU0_CANFAKCNAB3CYP4F2CYP2C9CYP2C8NP_001004074.1Q7M327_CANFACYP24A1UGT1A5Substrate-SGCYP4V2CHST14KCNAB1CHST11CYP46A1CYP4F11HS3ST4Substrate-GlUGT1A10CYP3A7Substrate-O-RUGT1A7CYP450CYP4F3CYP4X1CHST5NAT6CYP2A6AKR1A1NDST4HS6ST3GAL3ST4CYP26A1CYP21ACYP4F22HNMTUGT2B7CYP20A1UGT2B11NDST3EPHX2HS3ST3A1HS3ST5ST1B1_CANFAAldo-keto reductaseCYP26B1MGST1CHST13Substrate-NH2CYP2S1CP19A_CANFAHS6ST2UGT2B15CYP3A43HS6ST1CYP4B1FMO4CYP2C19CYP27A1SULT6B1CHST9NDST2NAT12UGT1A3HS3ST1ST1A1_CANFAST1A1_CANFAGPX5_CANFAAKR1C3CYP2F1UGT1A6HS3ST3B1BAATGlucuronosyltransferaseCYP3A5Q6PXD9_CANFACHST2NAT1GSTCDSULT1C3CYP2W1CYP4Z1CHST7


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP702(r29945) with a 65% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
118165view10:42, 25 May 2021EweitzModified title
87788view11:14, 25 July 2016ElisaOntology Term : 'classic metabolic pathway' added !
68588view23:15, 5 July 2013MaintBotUpdated to 2013 gpml schema
58854view23:35, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40747view21:54, 1 March 2011MaintBotRemoved redundant pathway information and comments
34019view18:45, 9 December 2009MaintBotAutomatic update of empty xrefs
33198view18:20, 5 November 2009KhanspersModified categories
32558view13:08, 17 August 2009MaintBotFixed text labels
32239view12:52, 15 August 2009MaintBotFixed text labels
31749view12:02, 14 August 2009MaintBotFixed group labels
31256view19:53, 13 August 2009MaintBotFixed text labels
30693view22:47, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKR1A1GeneProductENSCAFG00000004549 (Ensembl)
AKR1B10GeneProduct
AKR1B1GeneProductENSCAFG00000001290 (Ensembl)
AKR1C1GeneProduct
AKR1C2GeneProduct
AKR1C3GeneProduct497070 (Entrez Gene)
AKR1C4GeneProduct
AKR1D1GeneProduct491379 (Entrez Gene)
AKR7A2GeneProduct478210 (Entrez Gene)
AKR7A3GeneProduct
Aldo-keto reductaseGeneProduct
Amino acid acyltransferaseGeneProduct
BAATGeneProductENSCAFG00000023863 (Ensembl)
CHST10GeneProductENSCAFG00000002235 (Ensembl)
CHST11GeneProductENSCAFG00000024233 (Ensembl)
CHST12GeneProduct609635 (Entrez Gene)
CHST13GeneProductENSCAFG00000003870 (Ensembl)
CHST14GeneProduct608435 (Entrez Gene)
CHST1GeneProductENSCAFG00000009385 (Ensembl)
CHST2GeneProductENSCAFG00000008005 (Ensembl)
CHST3GeneProductENSCAFG00000014410 (Ensembl)
CHST4GeneProductENSCAFG00000020184 (Ensembl)
CHST5GeneProductENSCAFG00000020075 (Ensembl)
CHST6GeneProductENSCAFG00000020075 (Ensembl)
CHST7GeneProductENSCAFG00000014753 (Ensembl)
CHST8GeneProductENSCAFG00000024101 (Ensembl)
CHST9GeneProduct490506 (Entrez Gene)
CP19A_CANFAGeneProductENSCAFG00000015338 (Ensembl)
CP1A1_CANFAGeneProductENSCAFG00000017937 (Ensembl)
CP1A2_CANFAGeneProductENSCAFG00000017941 (Ensembl)
CP2BB_CANFAGeneProductENSCAFG00000005052 (Ensembl)
CP2E1_CANFAGeneProductENSCAFG00000013318 (Ensembl)
CYP11A1GeneProductENSCAFG00000017888 (Ensembl)
CYP17A1GeneProductENSCAFG00000010279 (Ensembl)
CYP1B1GeneProductENSCAFG00000006164 (Ensembl)
CYP20A1GeneProductENSCAFG00000012765 (Ensembl)
CYP21AGeneProduct415124 (Entrez Gene)
CYP24A1GeneProductENSCAFG00000011839 (Ensembl)
CYP26A1GeneProduct
CYP26B1GeneProductENSCAFG00000009005 (Ensembl)
CYP26C1GeneProductENSCAFG00000007574 (Ensembl)
CYP27A1GeneProductENSCAFG00000014943 (Ensembl)
CYP27B1GeneProductENSCAFG00000000287 (Ensembl)
CYP27C1GeneProductENSCAFG00000004542 (Ensembl)
CYP2A13GeneProduct484494 (Entrez Gene)
CYP2A6GeneProduct
CYP2A7GeneProduct
CYP2C18GeneProduct
CYP2C19GeneProduct
CYP2C8GeneProduct
CYP2C9GeneProduct
CYP2F1GeneProductENSCAFG00000023821 (Ensembl)
CYP2J2GeneProductENSCAFG00000018871 (Ensembl)
CYP2R1GeneProductENSCAFG00000008504 (Ensembl)
CYP2S1GeneProductENSCAFG00000005049 (Ensembl)
CYP2U1GeneProductENSCAFG00000011203 (Ensembl)
CYP2W1GeneProductENSCAFG00000011551 (Ensembl)
CYP39A1GeneProductENSCAFG00000002026 (Ensembl)
CYP3A4GeneProduct
CYP3A43GeneProduct
CYP3A5GeneProduct
CYP3A7GeneProduct
CYP450GeneProduct
CYP46A1GeneProductENSCAFG00000017838 (Ensembl)
CYP4B1GeneProductENSCAFG00000004097 (Ensembl)
CYP4F11GeneProductENSCAFG00000023401 (Ensembl)
CYP4F12GeneProductENSCAFG00000023401 (Ensembl)
CYP4F22GeneProductENSCAFG00000023053 (Ensembl)
CYP4F2GeneProductENSCAFG00000023401 (Ensembl)
CYP4F3GeneProduct
CYP4F8GeneProduct
CYP4V2GeneProductENSCAFG00000007384 (Ensembl)
CYP4X1GeneProductENSCAFG00000023824 (Ensembl)
CYP4Z1GeneProduct
CYP51A1GeneProductENSCAFG00000001945 (Ensembl)
CYP7A1GeneProductENSCAFG00000007098 (Ensembl)
CYP7B1GeneProductENSCAFG00000007246 (Ensembl)
CYP8B1GeneProductENSCAFG00000005370 (Ensembl)
EPHX2GeneProductENSCAFG00000008438 (Ensembl)
FMO1_CANFAGeneProductENSCAFG00000014982 (Ensembl)
FMO2GeneProductENSCAFG00000014986 (Ensembl)
FMO3_CANFAGeneProductENSCAFG00000014992 (Ensembl)
FMO4GeneProductENSCAFG00000014980 (Ensembl)
FMO5GeneProductENSCAFG00000010883 (Ensembl)
Flavin monooxygenaseGeneProduct
GAL3ST1GeneProductENSCAFG00000012779 (Ensembl)
GAL3ST2GeneProductENSCAFG00000013175 (Ensembl)
GAL3ST3GeneProductENSCAFG00000013061 (Ensembl)
GAL3ST4GeneProductENSCAFG00000014551 (Ensembl)
GLYATGeneProductENSCAFG00000007663 (Ensembl)
GLYATL1GeneProduct
GLYATL2GeneProduct
GPX1GeneProductENSCAFG00000011495 (Ensembl)
GPX2GeneProductENSCAFG00000016165 (Ensembl)
GPX3GeneProduct489179 (Entrez Gene)
GPX4GeneProduct
GPX5_CANFAGeneProductENSCAFG00000011947 (Ensembl)
GSRGeneProduct475596 (Entrez Gene)
GSTA4GeneProductENSCAFG00000024066 (Ensembl)
GSTCDGeneProductENSCAFG00000010916 (Ensembl)
GSTK1GeneProduct475518 (Entrez Gene)
GSTM1GeneProduct
GSTM2GeneProduct
GSTM3GeneProductENSCAFG00000019809 (Ensembl)
GSTM5GeneProduct
GSTO1GeneProductENSCAFG00000010593 (Ensembl)
GSTO2GeneProductENSCAFG00000024905 (Ensembl)
GSTP1GeneProduct
GSTT1GeneProductENSCAFG00000014034 (Ensembl)
GSTT2BGeneProductENSCAFG00000014043 (Ensembl)
GSTT2GeneProductENSCAFG00000014043 (Ensembl)
GSTZ1GeneProductENSCAFG00000017185 (Ensembl)
GlucuronosyltransferaseGeneProduct
Glutathione transferaseGeneProduct
HNMTGeneProductENSCAFG00000005178 (Ensembl)
HS2ST1GeneProductENSCAFG00000020234 (Ensembl)
HS3ST1GeneProduct403672 (Entrez Gene)
HS3ST2GeneProductENSCAFG00000017700 (Ensembl)
HS3ST3A1GeneProduct489512 (Entrez Gene)
HS3ST3B1GeneProduct489516 (Entrez Gene)
HS3ST4GeneProductENSCAFG00000023052 (Ensembl)
HS3ST5GeneProductENSCAFG00000004054 (Ensembl)
HS3ST6GeneProductENSCAFG00000024261 (Ensembl)
HS6ST1GeneProductENSCAFG00000004232 (Ensembl)
HS6ST2GeneProductENSCAFG00000018850 (Ensembl)
HS6ST3GeneProduct485526 (Entrez Gene)
INMTGeneProduct489397 (Entrez Gene)
KCNAB1GeneProductENSCAFG00000008838 (Ensembl)
KCNAB2GeneProductENSCAFG00000019524 (Ensembl)
KCNAB3GeneProductENSCAFG00000016888 (Ensembl)
MGST1GeneProductENSCAFG00000012619 (Ensembl)
MGST2GeneProductENSCAFG00000003702 (Ensembl)
MGST3GeneProductENSCAFG00000013353 (Ensembl)
MethyltransferaseGeneProduct
N-acetyltransferaseGeneProduct
NAT1GeneProduct
NAT10GeneProductENSCAFG00000007028 (Ensembl)
NAT11GeneProductENSCAFG00000014746 (Ensembl)
NAT12GeneProductENSCAFG00000015251 (Ensembl)
NAT13GeneProductENSCAFG00000010694 (Ensembl)
NAT14GeneProductENSCAFG00000002575 (Ensembl)
NAT2GeneProduct
NAT5GeneProductENSCAFG00000005357 (Ensembl)
NAT6GeneProductENSCAFG00000024499 (Ensembl)
NAT8GeneProductENSCAFG00000008808 (Ensembl)
NAT8LGeneProductENSCAFG00000014913 (Ensembl)
NAT9GeneProductENSCAFG00000004601 (Ensembl)
NDST1GeneProductENSCAFG00000023069 (Ensembl)
NDST2GeneProductENSCAFG00000015050 (Ensembl)
NDST3GeneProductENSCAFG00000012299 (Ensembl)
NDST4GeneProductENSCAFG00000012211 (Ensembl)
NNMTGeneProductENSCAFG00000013523 (Ensembl)
NP_001004074.1GeneProductENSCAFG00000014253 (Ensembl)
Q2VB21_CANFAGeneProductENSCAFG00000002230 (Ensembl)
Q3HTU0_CANFAGeneProductENSCAFG00000001285 (Ensembl)
Q6PXD9_CANFAGeneProductENSCAFG00000007671 (Ensembl)
Q70DT1_CANFAGeneProductENSCAFG00000000980 (Ensembl)
Q7M327_CANFAGeneProductENSCAFG00000016160 (Ensembl)
Q9TRV2_CANFAGeneProductENSCAFG00000019812 (Ensembl)
ST1A1_CANFAGeneProductENSCAFG00000017122 (Ensembl)
ST1B1_CANFAGeneProductENSCAFG00000002871 (Ensembl)
SULT1C2GeneProductENSCAFG00000002041 (Ensembl)
SULT1C3GeneProductENSCAFG00000023398 (Ensembl)
SULT1C4GeneProduct474542 (Entrez Gene)
SULT1C4GeneProductENSCAFG00000023655 (Ensembl)
SULT1E1GeneProductENSCAFG00000002878 (Ensembl)
SULT2A1GeneProduct
SULT2B1GeneProductENSCAFG00000003981 (Ensembl)
SULT4A1GeneProductENSCAFG00000000899 (Ensembl)
SULT6B1GeneProductENSCAFG00000006067 (Ensembl)
Substrate-AaMetabolite
Substrate-AcMetabolite
Substrate-CH3Metabolite
Substrate-GlMetabolite
Substrate-NH2Metabolite
Substrate-O-RMetabolite
Substrate-OHMetabolite
Substrate-SGMetabolite
Substrate-SHMetabolite
Substrate-SO3HMetabolite
Substrate=OMetabolite
SulfotransferaseGeneProduct
TPMT_CANFAGeneProductENSCAFG00000010160 (Ensembl)
UGT1A1GeneProduct
UGT1A10GeneProduct
UGT1A3GeneProduct
UGT1A4GeneProduct
UGT1A5GeneProduct
UGT1A6GeneProduct403629 (Entrez Gene)
UGT1A7GeneProduct
UGT1A8GeneProductENSCAFG00000015350 (Ensembl)
UGT1A9GeneProduct
UGT2A1GeneProduct475163 (Entrez Gene)
UGT2A2GeneProduct
UGT2A3GeneProduct
UGT2B11GeneProduct
UGT2B15GeneProduct
UGT2B17GeneProduct
UGT2B28GeneProduct
UGT2B4GeneProduct
UGT2B7GeneProduct
Xenobiotic substrateMetabolite

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1124"
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