Oxidative stress response (Canis familiaris)
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Induction of
antioxidant genes
Stress-regulated MAP kinase
TF activation
Repression
Immediate-early
gene induction
Inhibition of oxidases
Repression of ROS-
producing systems
Reactive Oxygen Species
Activation
Adaptive response
TF inhibition
NQO1
NFKB1
SOD1
CYBA
GSTT2
GCLC
GSR
TXNRD2
XDH
MAOA
GPX3
FOS
MGST1
JUNB
GPX1
UGT1A6
TXNRD1
SOD2
SP1
NFIX
CAT
HMOX1
MAPK14
Nrf2
TXN2
MT1X
MAPK10
SOD3
CYP1A1
Description
No description
Comments
GenMAPP notes
Adapted from Biochem J 1999 Sep 15;342 Pt 3:481-96 Morel Y, Barouki R. Repression of gene expression by oxidative stress. Biochem J 1999 Sep 15;342 Pt 3:481-96
GenMAPP remarks
Adapted from rat by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP408(r21540)
with a 79% conversion rate.
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Bibliography
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History
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Compare
Revision
Action
Time
User
Comment
117035
view
14:11, 16 May 2021
Eweitz
Modified title
88283
view
14:42, 1 August 2016
Fehrhart
Ontology Term : 'oxidative stress response pathway' added !
71466
view
19:17, 17 October 2013
MaintBot
Automated update of data sources
68540
view
22:26, 5 July 2013
MaintBot
Updated to 2013 gpml schema
40696
view
21:51, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33980
view
18:31, 9 December 2009
MaintBot
Automatic update of empty xrefs
32258
view
12:59, 15 August 2009
MaintBot
Fixed text labels
31780
view
12:11, 14 August 2009
MaintBot
Fixed group labels
31283
view
20:03, 13 August 2009
MaintBot
Fixed text labels
30735
view
23:01, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
CAT
GeneProduct
403474 (Entrez Gene)
CYBA
GeneProduct
489664 (Entrez Gene)
Probe set ID: u18729
CYP1A1
GeneProduct
487648 (Entrez Gene)
FOS
GeneProduct
490792 (Entrez Gene)
GCLC
GeneProduct
609822 (Entrez Gene)
GPX1
GeneProduct
442961 (Entrez Gene)
GPX3
GeneProduct
489179 (Entrez Gene)
GSR
GeneProduct
475596 (Entrez Gene)
GSTT2
GeneProduct
HMOX1
GeneProduct
442987 (Entrez Gene)
JUNB
GeneProduct
484927 (Entrez Gene)
MAOA
GeneProduct
403450 (Entrez Gene)
MAPK10
GeneProduct
478464 (Entrez Gene)
MAPK14
GeneProduct
403856 (Entrez Gene)
MGST1
GeneProduct
477683 (Entrez Gene)
MT1X
GeneProduct
NFIX
GeneProduct
484920 (Entrez Gene)
NFKB1
GeneProduct
442859 (Entrez Gene)
NQO1
GeneProduct
610935 (Entrez Gene)
Nrf2
GeneProduct
SOD1
GeneProduct
403559 (Entrez Gene)
SOD2
GeneProduct
476258 (Entrez Gene)
SOD3
GeneProduct
488855 (Entrez Gene)
SP1
GeneProduct
486507 (Entrez Gene)
TXN2
GeneProduct
474519 (Entrez Gene)
TXNRD1
GeneProduct
474536 (Entrez Gene)
TXNRD2
GeneProduct
608155 (Entrez Gene)
UGT1A6
GeneProduct
403629 (Entrez Gene)
XDH
GeneProduct
483028 (Entrez Gene)
Annotated Interactions
No annotated interactions
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View approved pathways at the new wikipathways.org.Quality Tags
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