Methylation (Mus musculus)

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Approved version The current version of this pathway was approved for data analysis by Maintenance bot.

Annotate nodes Comment: 4 out of 23 DataNodes have a missing external reference. Check DataNode table at the bottom of the page. Please help improve this pathway by annotating gene, protein and metabolite nodes.

Homology Converted Comment: Inferred from another species Revision {{{tag_revision}}} of this pathway has been inferred from another species (tagged by Maintenance bot). Expression error: Unrecognised punctuation character "{"

Ontology Terms

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Bibliography

1. Testa B, Kramer SD; ''The biochemistry of drug metabolism--an introduction: part 4. reactions of conjugation and their enzymes.''; Chem Biodivers, 2008 PubMed Europe PMC Scholia
2. Weinshilboum RM; ''Pharmacogenomics: catechol O-methyltransferase to thiopurine S-methyltransferase.''; Cell Mol Neurobiol, 2006 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
ATP	Metabolite	HMDB0000538 (HMDB)
Comt1	GeneProduct	ENSMUSG00000000326 (Ensembl)
Hnmt	GeneProduct	ENSMUSG00000026986 (Ensembl)
Inmt	GeneProduct	ENSMUSG00000003477 (Ensembl)
L-Methionine	Metabolite	HMDB0000696 (HMDB)
Mat1a	GeneProduct	ENSMUSG00000037798 (Ensembl)
Mat2a	GeneProduct	ENSMUSG00000053907 (Ensembl)
Mat2b	GeneProduct	ENSMUSG00000042032 (Ensembl)
N-methylated substrate	Metabolite
Nnmt	GeneProduct	ENSMUSG00000032271 (Ensembl)
O-methylated substrate	Metabolite
Phosphate	Metabolite	HMDB0001429 (HMDB)
Pnmt	GeneProduct	ENSMUSG00000038216 (Ensembl)
S-Adenosylhomocysteine	Metabolite	HMDB0000939 (HMDB)
S-Adenosylmethionine	Metabolite	HMDB0001185 (HMDB)
S-methylated substrate	Metabolite
Substrate	Metabolite
Tpmt	GeneProduct	ENSMUSG00000021376 (Ensembl)

Annotated Interactions