Metapathway biotransformation (Mus musculus)

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Glutathione reductaseN-acetyltransferasesAldo-keto reductasesGlutathione transferasesGlucuronidationGlutathione peroxidasesAmino acid conjugationFlavin monooxygenasesGlutathione synthetaseEpoxide hydrolasesCytochrome P450MethylationMethyltransferasesOxidationGlucuronosyltransferasesSulfotransferasesReductionHydrolysisSulfationNucleophilesAcetylationGlutathione conjugationElectrophilesAmino acid acyl transferasesMgst1Hs3st2Cyp46a1Cyp2f2Nat6Cyp11a1CYP11B1CYP4F12AC154274.1-1AKR7A3Chst3HS3ST3B1Cyp4f18Cyp4x1Gal3st1Ugt2a2UGT1A10Substrate-CH3SulfotransferaseChst8AC140307.3-1Akr1a4GAL3ST2AC161058.2-1Sult1a1Ndst3Nat14UGT2B17Sult1c2Nat12Ndst4Chst11UGT1A9UGT2B7CYP4F11Sult1a1AKR1C1Cyp8b1HnmtAkr7a5Ndst1Gstm7CYP2C18Cyp24a1AKR1C4Chst14Nat10CYP2B6UGT1A5CYP2A7Hs6st3Gstm5GSTP1Nat8lUGT2B4Ndst2Substrate-NH2SULT2A1Chst5Cyp1a1Gpx3CYP2C8Xenobiotic substrateSULT1C2CYP4Z1CYP3A4Hs3st5Substrate=OUgt1a2GSTA5Cyp51Cyp19a1CYP2A6UGT1A7Substrate-O-RChst2Cyp4v3Fmo1AKR1C2Gstt2Sult1b1Cyp26a1Chst9CYP2J2InmtUgt1a10GlyatFmo4CYP2A13Ugt1a5CYP2C19Substrate-AcSult1e1Gpx4Hs6st2Substrate-AaGSTA4Hs2st1Kcnab2Ephx2Cyp20a1Cyp21a1Ugt2a3UGT2B15Nat13Gal3st3Comt1Chst12Mgst3GLYATL2Ugt1a1AKR1B10CYP4F8NnmtCYP2C9CYP3A7CYP3A5Gstz1Flavin monooxygenaseSULT1C4CYP27C1CYP2D6Cyp39a1Gstt2GLYATL1Cyp4f39Cyp2u1AC122521.4GssSubstrate-SO3HFmo2Gpx1GstcdAkr1d1Cyp7a1Chst1Substrate-OHKcnab1AKR1C3GSTM1Cyp2s1CYP4F2NAT8Cyp26c1Gstt1Hs3st6HS3ST3A1GSTM4Chst10Cyp17a1Gal3st4N-acetyltransferaseBaatKcnab3Gsto1Nat9SULT1C3Hs3st1GsrSult4a1Gsto2Aldo-keto reductaseCYP3A43Sult1a1Gpx5Ephx1Substrate-SHGpx2Hs6st1Hs3st4Cyp27b1Mgst2Chst5Cyp1a2Glutathione transferaseNat5Substrate-GlChst4Cyp7b1GlucuronosyltransferaseCyp27a1Chst7Akr1b3UGT2A2UGT2B11MethyltransferaseCyp2e1GSTA1GSTA3Cyp2r1Cyp4b1Sult2b1CYP450Fmo3GSTM5Substrate-SGUGT1A6Cyp1b1UGT2B28Cyp26b1Gstk1Sult1a1NAT2GSTA2Amino acid acyltransferaseTpmtCYP11B2NAT1Fmo5


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP702(r29945) with a 64% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
94721view14:08, 5 October 2017EgonwConverted two complexes (which they are not) to groups.
94720view14:04, 5 October 2017EgonwMim-typed interactions.
69747view09:37, 11 July 2013EgonwAdded ChEBI identifiers for a few compound classes.
69160view18:19, 8 July 2013MaintBotUpdated to 2013 gpml schema
67456view11:04, 26 June 2013DdiglesOntology Term : 'cellular detoxification pathway' added !
59060view21:01, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
58513view19:13, 14 February 2013MaintBotModified title
41349view00:26, 2 March 2011MaintBotRemoved redundant pathway information and comments
34408view23:07, 9 December 2009MaintBotAutomatic update of empty xrefs
33190view18:06, 5 November 2009KhanspersModified categories
32293view13:12, 15 August 2009MaintBotFixed text labels
31856view12:33, 14 August 2009MaintBotFixed group labels
31321view20:17, 13 August 2009MaintBotFixed text labels
30847view00:06, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AC122521.4GeneProductENSMUSG00000056643 (Ensembl)
AC140307.3-1GeneProductENSMUSG00000024764 (Ensembl)
AC154274.1-1GeneProductENSMUSG00000038045 (Ensembl)
AC161058.2-1GeneProductENSMUSG00000029541 (Ensembl)
AKR1B10GeneProduct67861 (Entrez Gene)
AKR1C1GeneProduct
AKR1C2GeneProduct
AKR1C3GeneProduct
AKR1C4GeneProduct
AKR7A3GeneProduct
Akr1a4GeneProductENSMUSG00000028692 (Ensembl)
Akr1b3GeneProductENSMUSG00000001642 (Ensembl)
Akr1d1GeneProductENSMUSG00000038641 (Ensembl)
Akr7a5GeneProductENSMUSG00000028743 (Ensembl)
Aldo-keto reductaseGeneProduct
Amino acid acyltransferaseGeneProduct
BaatGeneProductENSMUSG00000039653 (Ensembl)
CYP11B1GeneProduct110115 (Entrez Gene)
CYP11B2GeneProduct13072 (Entrez Gene)
CYP27C1GeneProduct
CYP2A13GeneProduct
CYP2A6GeneProduct
CYP2A7GeneProduct
CYP2B6GeneProduct
CYP2C18GeneProduct
CYP2C19GeneProduct
CYP2C8GeneProduct
CYP2C9GeneProduct
CYP2D6GeneProduct
CYP2J2GeneProduct
CYP3A4GeneProduct
CYP3A43GeneProduct
CYP3A5GeneProduct
CYP3A7GeneProduct
CYP450GeneProduct
CYP4F11GeneProduct
CYP4F12GeneProduct
CYP4F2GeneProduct
CYP4F8GeneProduct
CYP4Z1GeneProduct
Chst10GeneProductENSMUSG00000026080 (Ensembl)
Chst11GeneProductENSMUSG00000034612 (Ensembl)
Chst12GeneProductENSMUSG00000036599 (Ensembl)
Chst14GeneProduct72136 (Entrez Gene)
Chst1GeneProductENSMUSG00000027221 (Ensembl)
Chst2GeneProductENSMUSG00000033350 (Ensembl)
Chst3GeneProductENSMUSG00000057337 (Ensembl)
Chst4GeneProductENSMUSG00000035930 (Ensembl)
Chst5GeneProductENSMUSG00000031952 (Ensembl)
Chst7GeneProductENSMUSG00000037347 (Ensembl)
Chst8GeneProductENSMUSG00000060402 (Ensembl)
Chst9GeneProduct71367 (Entrez Gene)
Comt1GeneProductENSMUSG00000000326 (Ensembl)
Cyp11a1GeneProductENSMUSG00000032323 (Ensembl)
Cyp17a1GeneProductENSMUSG00000003555 (Ensembl)
Cyp19a1GeneProductENSMUSG00000032274 (Ensembl)
Cyp1a1GeneProductENSMUSG00000032315 (Ensembl)
Cyp1a2GeneProductENSMUSG00000032310 (Ensembl)
Cyp1b1GeneProductENSMUSG00000024087 (Ensembl)
Cyp20a1GeneProductENSMUSG00000049439 (Ensembl)
Cyp21a1GeneProduct13079 (Entrez Gene)
Cyp24a1GeneProductENSMUSG00000038567 (Ensembl)
Cyp26a1GeneProductENSMUSG00000024987 (Ensembl)
Cyp26b1GeneProductENSMUSG00000063415 (Ensembl)
Cyp26c1GeneProductENSMUSG00000062432 (Ensembl)
Cyp27a1GeneProductENSMUSG00000026170 (Ensembl)
Cyp27b1GeneProductENSMUSG00000006724 (Ensembl)
Cyp2e1GeneProductENSMUSG00000025479 (Ensembl)
Cyp2f2GeneProductENSMUSG00000052974 (Ensembl)
Cyp2r1GeneProductENSMUSG00000030670 (Ensembl)
Cyp2s1GeneProductENSMUSG00000040703 (Ensembl)
Cyp2u1GeneProductENSMUSG00000027983 (Ensembl)
Cyp39a1GeneProductENSMUSG00000023963 (Ensembl)
Cyp46a1GeneProductENSMUSG00000021259 (Ensembl)
Cyp4b1GeneProductENSMUSG00000028713 (Ensembl)
Cyp4f18GeneProductENSMUSG00000003484 (Ensembl)
Cyp4f39GeneProductENSMUSG00000061126 (Ensembl)
Cyp4v3GeneProductENSMUSG00000079057 (Ensembl)
Cyp4x1GeneProductENSMUSG00000047155 (Ensembl)
Cyp51GeneProductENSMUSG00000001467 (Ensembl)
Cyp7a1GeneProductENSMUSG00000028240 (Ensembl)
Cyp7b1GeneProductENSMUSG00000039519 (Ensembl)
Cyp8b1GeneProductENSMUSG00000050445 (Ensembl)
Ephx1GeneProductENSMUSG00000038776 (Ensembl)
Ephx2GeneProductENSMUSG00000022040 (Ensembl)
Flavin monooxygenaseGeneProduct
Fmo1GeneProductENSMUSG00000040181 (Ensembl)
Fmo2GeneProductENSMUSG00000040170 (Ensembl)
Fmo3GeneProductENSMUSG00000026691 (Ensembl)
Fmo4GeneProductENSMUSG00000026692 (Ensembl)
Fmo5GeneProductENSMUSG00000028088 (Ensembl)
GAL3ST2GeneProduct381334 (Entrez Gene)
GLYATL1GeneProduct
GLYATL2GeneProduct
GSTA1GeneProduct14857 (Entrez Gene)
GSTA2GeneProduct14858 (Entrez Gene)
GSTA3GeneProduct14859 (Entrez Gene)
GSTA4GeneProduct14860 (Entrez Gene)
GSTA5GeneProduct
GSTM1GeneProduct14862 (Entrez Gene)
GSTM4GeneProduct14865 (Entrez Gene)
GSTM5GeneProduct14866 (Entrez Gene)
GSTP1GeneProduct14870 (Entrez Gene)
Gal3st1GeneProductENSMUSG00000049721 (Ensembl)
Gal3st3GeneProductENSMUSG00000047658 (Ensembl)
Gal3st4GeneProductENSMUSG00000075593 (Ensembl)
GlucuronosyltransferaseGeneProduct
Glutathione transferaseGeneProduct
GlyatGeneProductENSMUSG00000063683 (Ensembl)
Gpx1GeneProductENSMUSG00000063856 (Ensembl)
Gpx2GeneProductENSMUSG00000042808 (Ensembl)
Gpx3GeneProductENSMUSG00000018339 (Ensembl)
Gpx4GeneProductENSMUSG00000075706 (Ensembl)
Gpx5GeneProductENSMUSG00000004344 (Ensembl)
GsrGeneProductENSMUSG00000031584 (Ensembl)
GssGeneProductENSMUSG00000027610 (Ensembl)
GstcdGeneProductENSMUSG00000028018 (Ensembl)
Gstk1GeneProductENSMUSG00000029864 (Ensembl)
Gstm5GeneProductENSMUSG00000004032 (Ensembl)
Gstm7GeneProductENSMUSG00000004035 (Ensembl)
Gsto1GeneProductENSMUSG00000025068 (Ensembl)
Gsto2GeneProductENSMUSG00000025069 (Ensembl)
Gstt1GeneProductENSMUSG00000001663 (Ensembl)
Gstt2GeneProductENSMUSG00000033318 (Ensembl)
Gstz1GeneProductENSMUSG00000021033 (Ensembl)
HS3ST3A1GeneProduct15478 (Entrez Gene)
HS3ST3B1GeneProduct54710 (Entrez Gene)
HnmtGeneProductENSMUSG00000026986 (Ensembl)
Hs2st1GeneProductENSMUSG00000040151 (Ensembl)
Hs3st1GeneProductENSMUSG00000051022 (Ensembl)
Hs3st2GeneProductENSMUSG00000046321 (Ensembl)
Hs3st4GeneProductENSMUSG00000078591 (Ensembl)
Hs3st5GeneProductENSMUSG00000044499 (Ensembl)
Hs3st6GeneProductENSMUSG00000039628 (Ensembl)
Hs6st1GeneProductENSMUSG00000045216 (Ensembl)
Hs6st2GeneProductENSMUSG00000062184 (Ensembl)
Hs6st3GeneProductENSMUSG00000053465 (Ensembl)
InmtGeneProductENSMUSG00000003477 (Ensembl)
Kcnab1GeneProductENSMUSG00000027827 (Ensembl)
Kcnab2GeneProductENSMUSG00000028931 (Ensembl)
Kcnab3GeneProductENSMUSG00000018470 (Ensembl)
MethyltransferaseGeneProduct
Mgst1GeneProductENSMUSG00000008540 (Ensembl)
Mgst2GeneProductENSMUSG00000074604 (Ensembl)
Mgst3GeneProductENSMUSG00000026688 (Ensembl)
N-acetyltransferaseGeneProduct
NAT1GeneProduct
NAT2GeneProduct17961 (Entrez Gene)
NAT8GeneProduct68396 (Entrez Gene)
Nat10GeneProductENSMUSG00000027185 (Ensembl)
Nat12GeneProductENSMUSG00000036282 (Ensembl)
Nat13GeneProductENSMUSG00000022698 (Ensembl)
Nat14GeneProductENSMUSG00000035285 (Ensembl)
Nat5GeneProductENSMUSG00000002728 (Ensembl)
Nat6GeneProductENSMUSG00000079334 (Ensembl)
Nat8lGeneProductENSMUSG00000048142 (Ensembl)
Nat9GeneProductENSMUSG00000015542 (Ensembl)
Ndst1GeneProductENSMUSG00000054008 (Ensembl)
Ndst2GeneProductENSMUSG00000039308 (Ensembl)
Ndst3GeneProductENSMUSG00000027977 (Ensembl)
Ndst4GeneProductENSMUSG00000027971 (Ensembl)
NnmtGeneProductENSMUSG00000032271 (Ensembl)
SULT1C2GeneProduct69083 (Entrez Gene)
SULT1C3GeneProduct
SULT1C4GeneProduct
SULT2A1GeneProduct20859 (Entrez Gene)
Substrate-AaMetabolite
Substrate-AcMetabolite
Substrate-CH3Metabolite
Substrate-GlMetabolite
Substrate-NH2MetaboliteCHEBI:50047 (ChEBI)
Substrate-O-RMetaboliteCHEBI:25698 (ChEBI)
Substrate-OHMetaboliteCHEBI:30879 (ChEBI)
Substrate-SGMetabolite
Substrate-SHMetaboliteCHEBI:29256 (ChEBI)
Substrate-SO3HMetabolite
Substrate=OMetaboliteCHEBI:36586 (ChEBI)
SulfotransferaseGeneProduct
Sult1a1GeneProductENSMUSG00000030711 (Ensembl)
Sult1b1GeneProductENSMUSG00000029269 (Ensembl)
Sult1c2GeneProductENSMUSG00000023122 (Ensembl)
Sult1e1GeneProductENSMUSG00000029272 (Ensembl)
Sult2b1GeneProductENSMUSG00000003271 (Ensembl)
Sult4a1GeneProductENSMUSG00000018865 (Ensembl)
TpmtGeneProductENSMUSG00000021376 (Ensembl)
UGT1A10GeneProduct394430 (Entrez Gene)
UGT1A5GeneProduct394433 (Entrez Gene)
UGT1A6GeneProduct
UGT1A7GeneProduct
UGT1A9GeneProduct394434 (Entrez Gene)
UGT2A2GeneProduct552899 (Entrez Gene)
UGT2B11GeneProduct
UGT2B15GeneProduct
UGT2B17GeneProduct
UGT2B28GeneProduct
UGT2B4GeneProduct
UGT2B7GeneProduct
Ugt1a10GeneProductENSMUSG00000054545 (Ensembl)
Ugt1a1GeneProduct394436 (Entrez Gene)
Ugt1a2GeneProduct22236 (Entrez Gene)
Ugt1a5GeneProduct394433 (Entrez Gene)
Ugt2a2GeneProductENSMUSG00000029268 (Ensembl)
Ugt2a3GeneProductENSMUSG00000035780 (Ensembl)
Xenobiotic substrateMetabolite

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1251"
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