T cell receptor signaling pathway (Danio rerio)

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Reaction through unknown mechanisms/moleculesLigandDDemethylationNUMethylationMolecular associationPMAutophosphorylationNU->CYAcetylationAccession Number: NetPath_11Endoplasmic reticulumGOPalmitoylationUbiquitinationGlycosylationDeubiquitinationMolecule in the pathwayActivationDephosphorylationRecruitmentProteolytic cleavageSumoylationNucleusExtracellularCytoplasmEndosomeECGene SymbolControlInhibitionCY->NUERDesumoylationENPhosphorylationDGolgi apparatusProteins in a complex interactionCY->PMTranslocationAntigenMT(Protein-protein interaction)Plasma membraneMitochondrionCY->NUDeacetylationEnzyme complexReceptorCYoxsr1arac2LAX1CD3EMAP4K1STAT5AjunYWHAQzgc:63721cblbLOC564517PTPRHARHGEF7LOC100151491mapk1LOC100003365CD3ZbrafSHBPPP3CBLOC100149388ripk2MUC1LATptpn6LOC100000720cdc42lptk2.1cebpbLOC100000665zgc:110383DKEY-234H16.4creb1DTX1zgc:112450sla1LOC798084mapk7GRAPptk2bbitkLOC563639dnm2lPTPN12NFAM1tuba8l2zgc:92124CD2LOC564899LCKSTAT5BRASGRP2SH2D2Acbltubb5CH211-127H20.2pxncd2aplPTPN3zgc:158223CD8Askap2zgc:162320fosCD3DcrebbpbDOCK2ENAHzgc:55557ctnnb1fynbPRKD2rasa1sykplcg1VAV2FCRL3LOC571865TRB@NEDD9CD4wu:fk86g11sh2d3caTXKLOC557176UNC119junLOC792354JAK3evlbrap1agrb2zgc:172250ptpn11stat1asi:dkey-24l11.5LOC557072pak1crkHDAC7AarhgdigKHDRBS1HDAC7ACD3GSOS1zgc:110844mapk3zgc:101809CD3EPRKCQpik3r2TRAT1LIME1TRA@CD5LOC796938CD3ZcrklWASF2ptprjazgc:153534map2k1STAT5ACH211-67F24.8VAV1zgc:112091zgc:101809zgc:171590LIME1PTPRCncldlg1LNKSTAT5BNCK1LOC796938NCK1SIT1LOC793398wu:fb79a07srccishsi:dkey-78k11.1LOC558288wasb


Description

No description

Comments

GenMAPP notes 
NetPath_11 - T Cell Receptor Signaling Pathway NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP69(r20823) with a 60% conversion rate.

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Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
116910view11:48, 15 May 2021EweitzModified title
87698view08:59, 25 July 2016MirellaKalafatiOntology Term : 'signaling pathway' added !
87697view08:59, 25 July 2016MirellaKalafatiOntology Term : 'T cell' added !
68678view05:36, 6 July 2013MaintBotUpdated to 2013 gpml schema
40851view22:19, 1 March 2011MaintBotRemoved redundant pathway information and comments
34233view21:38, 9 December 2009MaintBotAutomatic update of empty xrefs
31362view20:34, 13 August 2009MaintBotFixed text labels
31055view01:23, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGEF7GeneProduct
CD2GeneProduct
CD3DGeneProduct
CD3EGeneProduct
CD3GGeneProduct
CD3ZGeneProduct
CD4GeneProduct
CD5GeneProduct
CD8AGeneProduct677754 (Entrez Gene)
CH211-127H20.2GeneProduct558635 (Entrez Gene)
CH211-67F24.8GeneProduct561670 (Entrez Gene)
DKEY-234H16.4GeneProduct793882 (Entrez Gene)
DOCK2GeneProduct571408 (Entrez Gene)
DTX1GeneProduct570481 (Entrez Gene)
ENAHGeneProduct563805 (Entrez Gene)
FCRL3GeneProduct
GRAPGeneProduct553596 (Entrez Gene)
HDAC7AGeneProduct
JAK3GeneProduct561370 (Entrez Gene)
KHDRBS1GeneProduct
LATGeneProduct100233211 (Entrez Gene)
LAX1GeneProduct
LCKGeneProduct414333 (Entrez Gene)
LIME1GeneProduct
LNKGeneProduct
LOC100000665GeneProduct100000665 (Entrez Gene)
LOC100000720GeneProduct100000720 (Entrez Gene)
LOC100003365GeneProduct100003365 (Entrez Gene)
LOC100149388GeneProduct100149388 (Entrez Gene)
LOC100151491GeneProduct100151491 (Entrez Gene)
LOC557072GeneProduct557072 (Entrez Gene)
LOC557176GeneProduct557176 (Entrez Gene)
LOC558288GeneProduct558288 (Entrez Gene)
LOC563639GeneProduct563639 (Entrez Gene)
LOC564517GeneProduct564517 (Entrez Gene)
LOC564899GeneProduct564899 (Entrez Gene)
LOC571865GeneProduct571865 (Entrez Gene)
LOC792354GeneProduct792354 (Entrez Gene)
LOC793398GeneProduct793398 (Entrez Gene)
LOC796938GeneProduct796938 (Entrez Gene)
LOC798084GeneProduct798084 (Entrez Gene)
MAP4K1GeneProduct
MUC1GeneProduct
NCK1GeneProduct
NEDD9GeneProduct
NFAM1GeneProduct
PPP3CBGeneProduct
PRKCQGeneProduct555521 (Entrez Gene)
PRKD2GeneProduct
PTPN12GeneProduct393642 (Entrez Gene)
PTPN3GeneProduct407635 (Entrez Gene)
PTPRCGeneProduct559154 (Entrez Gene)
PTPRHGeneProduct
RASGRP2GeneProduct
SH2D2AGeneProduct
SHBGeneProduct
SIT1GeneProduct
SOS1GeneProduct
STAT5AGeneProduct
STAT5BGeneProduct
TRA@GeneProduct
TRAT1GeneProduct
TRB@GeneProduct
TXKGeneProduct
UNC119GeneProduct
VAV1GeneProduct
VAV2GeneProduct
WASF2GeneProduct
YWHAQGeneProduct
arhgdigGeneProduct394132 (Entrez Gene)
brafGeneProduct403065 (Entrez Gene)
cblGeneProduct492364 (Entrez Gene)
cblbGeneProduct556277 (Entrez Gene)
cd2aplGeneProduct494040 (Entrez Gene)
cdc42lGeneProduct793158 (Entrez Gene)
cebpbGeneProduct140814 (Entrez Gene)
cishGeneProduct767678 (Entrez Gene)
creb1GeneProduct573207 (Entrez Gene)
crebbpbGeneProduct503776 (Entrez Gene)
crkGeneProduct445234 (Entrez Gene)
crklGeneProduct556443 (Entrez Gene)
ctnnb1GeneProduct30265 (Entrez Gene)
dlg1GeneProduct114446 (Entrez Gene)
dnm2lGeneProduct406525 (Entrez Gene)
evlbGeneProduct402929 (Entrez Gene)
fosGeneProduct394198 (Entrez Gene)
fynbGeneProduct574422 (Entrez Gene)
grb2GeneProduct406308 (Entrez Gene)
itkGeneProduct798906 (Entrez Gene)
junGeneProduct335916 (Entrez Gene)
map2k1GeneProduct406728 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mapk3GeneProduct399480 (Entrez Gene)
mapk7GeneProduct541323 (Entrez Gene)
nclGeneProduct767714 (Entrez Gene)
oxsr1aGeneProduct568602 (Entrez Gene)
pak1GeneProduct373103 (Entrez Gene)
pik3r2GeneProduct404211 (Entrez Gene)
plcg1GeneProduct373867 (Entrez Gene)
ptk2.1GeneProduct142986 (Entrez Gene)
ptk2bbGeneProduct245950 (Entrez Gene)
ptpn11GeneProduct333979 (Entrez Gene)
ptpn6GeneProduct335573 (Entrez Gene)
ptprjaGeneProduct559679 (Entrez Gene)
pxnGeneProduct399546 (Entrez Gene)
rac2GeneProduct415151 (Entrez Gene)
rap1aGeneProduct415242 (Entrez Gene)
rasa1GeneProduct100002155 (Entrez Gene)
ripk2GeneProduct373874 (Entrez Gene)
sh2d3caGeneProduct558860 (Entrez Gene)
si:dkey-24l11.5GeneProduct571331 (Entrez Gene)
si:dkey-78k11.1GeneProduct565606 (Entrez Gene)
skap2GeneProduct368564 (Entrez Gene)
sla1GeneProduct571922 (Entrez Gene)
srcGeneProduct325084 (Entrez Gene)
stat1aGeneProduct30768 (Entrez Gene)
sykGeneProduct405769 (Entrez Gene)
tuba8l2GeneProduct393664 (Entrez Gene)
tubb5GeneProduct386701 (Entrez Gene)
wasbGeneProduct335158 (Entrez Gene)
wu:fb79a07GeneProduct571383 (Entrez Gene)
wu:fk86g11GeneProduct559145 (Entrez Gene)
zgc:101809GeneProduct336073 (Entrez Gene)
zgc:110383GeneProduct553615 (Entrez Gene)
zgc:110844GeneProduct541489 (Entrez Gene)
zgc:112091GeneProduct550452 (Entrez Gene)
zgc:112450GeneProduct553729 (Entrez Gene)
zgc:153534GeneProduct767738 (Entrez Gene)
zgc:158223GeneProduct563784 (Entrez Gene)
zgc:162320GeneProduct555805 (Entrez Gene)
zgc:171590GeneProduct568515 (Entrez Gene)
zgc:172250GeneProduct100002225 (Entrez Gene)
zgc:55557GeneProduct394088 (Entrez Gene)
zgc:63721GeneProduct394015 (Entrez Gene)
zgc:92124GeneProduct447804 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1345"
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