IL-3 signaling pathway (Danio rerio)

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MADemethylationReceptorDMTDEndosomeDDesumoylationDMANUDDRecruitmentERPMMolecular AssociationDPalmitoylationEndoplasmic reticulumGolgi apparatusGODCY->PMDENDUbiquitinationEnzyme complexAccession Number: NetPath 15GlycosylationMolecule in the pathwayCY->NUDCY->NUPhosphorylationProteolytic cleavageCY->PMActivationDephosphorylationCY->PMCYMT->CYControl(Protein-protein interaction)DMAAutophosphorylationDMAMethylationDeacetylationSumoylationMAExtracellularDMitochondrionProteins in a complex interactionAcetylationInhibitionDDPlasma membraneDDNucleusLigandReaction through unknown mechanisms/moleculesTranslocationDeubiquitinationCytoplasmECDMABCL2L11IL3RAsocs2RARAzgc:172209SOS1CSF2RBLCKTYK2IL3rac1ptpn11chek1zgc:56064LOC559103IL3SOCS3NFKB1LOC563639spi1CH211-127H20.2Gene SymbolVAV1pxnRPS6KB2atf1LOC563639prkcb1PILRBrxraamapk3hspb1LOC561737mapk14ajak2brac2FOXO1ABAXbcl2lfynbsrcCH211-63J24.2LOC796481IL3RAdnm2LOC100149498mapk3mmp2jak1FEScrkcishrap1amrasbirc5ammp9grb2ptk2.1zgc:92124YWHAQBADSTAT5BvclLOC100149498cblLOC566983pik3r2GSK3AIL3mapk7crklLOC557176mapkapk2aBCL2slc2a1stat1aLOC569951stat3NFKB1map2k1YWHAZpak1zgc:158799gsk3bslc2a1STAT5Agata2apik3cdIL3CSF2RBzgc:175287creb1LOC564517FCER2LOC100149273ptpn6gnb2l1HRASGATA1BMXraf1id1KCNIP3atf2lBADLOC796190cdc42lsykLOC792354gab1YWHABkrasmapk1


Description

No description

Comments

GenMAPP notes 
NetPath:15 - IL-3 Signaling Pathway. NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP286(r21281) with a 67% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
116885view11:06, 15 May 2021EweitzModified title
86926view13:01, 15 July 2016MkutmonOntology Term : 'interleukin-3 signaling pathway' added !
68619view04:06, 6 July 2013MaintBotUpdated to 2013 gpml schema
40782view22:15, 1 March 2011MaintBotRemoved redundant pathway information and comments
34173view21:19, 9 December 2009MaintBotAutomatic update of empty xrefs
31372view20:38, 13 August 2009MaintBotFixed text labels
31070view01:29, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
BADGeneProduct58100 (Entrez Gene)
BAXGeneProduct
BCL2GeneProduct570772 (Entrez Gene)
BCL2L11GeneProduct100190951 (Entrez Gene)
BMXGeneProduct
CH211-127H20.2GeneProduct558635 (Entrez Gene)
CH211-63J24.2GeneProduct567405 (Entrez Gene)
CSF2RBGeneProduct100135062 (Entrez Gene)
FCER2GeneProduct
FESGeneProduct
FOXO1AGeneProduct768121 (Entrez Gene)
GATA1GeneProduct30481 (Entrez Gene)
GSK3AGeneProduct30664 (Entrez Gene)
Gene SymbolGeneProduct
HRASGeneProduct550286 (Entrez Gene)
IL3GeneProduct
IL3RAGeneProduct
KCNIP3GeneProduct393755 (Entrez Gene)
LCKGeneProduct414333 (Entrez Gene)
LOC100149273GeneProduct100149273 (Entrez Gene)
LOC100149498GeneProduct100149498 (Entrez Gene)
LOC557176GeneProduct557176 (Entrez Gene)
LOC559103GeneProduct559103 (Entrez Gene)
LOC561737GeneProduct561737 (Entrez Gene)
LOC563639GeneProduct563639 (Entrez Gene)
LOC564517GeneProduct564517 (Entrez Gene)
LOC566983GeneProduct566983 (Entrez Gene)
LOC569951GeneProduct569951 (Entrez Gene)
LOC792354GeneProduct792354 (Entrez Gene)
LOC796190GeneProduct796190 (Entrez Gene)
LOC796481GeneProduct796481 (Entrez Gene)
NFKB1GeneProduct565756 (Entrez Gene)
PILRBGeneProduct
RARAGeneProduct
RPS6KB2GeneProduct
SOCS3GeneProduct
SOS1GeneProduct
STAT5AGeneProduct
STAT5BGeneProduct
TYK2GeneProduct
VAV1GeneProduct
YWHABGeneProduct
YWHAQGeneProduct
YWHAZGeneProduct
atf1GeneProduct325609 (Entrez Gene)
atf2lGeneProduct100006516 (Entrez Gene)
bcl2lGeneProduct114401 (Entrez Gene)
birc5aGeneProduct373110 (Entrez Gene)
cblGeneProduct492364 (Entrez Gene)
cdc42lGeneProduct793158 (Entrez Gene)
chek1GeneProduct393162 (Entrez Gene)
cishGeneProduct767678 (Entrez Gene)
creb1GeneProduct573207 (Entrez Gene)
crkGeneProduct445234 (Entrez Gene)
crklGeneProduct556443 (Entrez Gene)
dnm2GeneProduct559334 (Entrez Gene)
fynbGeneProduct574422 (Entrez Gene)
gab1GeneProduct406666 (Entrez Gene)
gata2aGeneProduct30480 (Entrez Gene)
gnb2l1GeneProduct30722 (Entrez Gene)
grb2GeneProduct406308 (Entrez Gene)
gsk3bGeneProduct30654 (Entrez Gene)
hspb1GeneProduct368243 (Entrez Gene)
id1GeneProduct30493 (Entrez Gene)
jak1GeneProduct30280 (Entrez Gene)
jak2bGeneProduct30298 (Entrez Gene)
krasGeneProduct445289 (Entrez Gene)
map2k1GeneProduct406728 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mapk14aGeneProduct65237 (Entrez Gene)
mapk3GeneProduct399480 (Entrez Gene)
mapk7GeneProduct541323 (Entrez Gene)
mapkapk2aGeneProduct327321 (Entrez Gene)
mmp2GeneProduct337179 (Entrez Gene)
mmp9GeneProduct406397 (Entrez Gene)
mrasGeneProduct564799 (Entrez Gene)
pak1GeneProduct373103 (Entrez Gene)
pik3cdGeneProduct394174 (Entrez Gene)
pik3r2GeneProduct404211 (Entrez Gene)
prkcb1GeneProduct393953 (Entrez Gene)
ptk2.1GeneProduct142986 (Entrez Gene)
ptpn11GeneProduct333979 (Entrez Gene)
ptpn6GeneProduct335573 (Entrez Gene)
pxnGeneProduct399546 (Entrez Gene)
rac1GeneProduct327204 (Entrez Gene)
rac2GeneProduct415151 (Entrez Gene)
raf1GeneProduct30716 (Entrez Gene)
rap1aGeneProduct415242 (Entrez Gene)
rxraaGeneProduct555578 (Entrez Gene)
slc2a1GeneProduct555778 (Entrez Gene)
socs2GeneProduct562062 (Entrez Gene)
spi1GeneProduct30117 (Entrez Gene)
srcGeneProduct325084 (Entrez Gene)
stat1aGeneProduct30768 (Entrez Gene)
stat3GeneProduct30767 (Entrez Gene)
sykGeneProduct405769 (Entrez Gene)
vclGeneProduct552980 (Entrez Gene)
zgc:158799GeneProduct564064 (Entrez Gene)
zgc:172209GeneProduct562720 (Entrez Gene)
zgc:175287GeneProduct571588 (Entrez Gene)
zgc:56064GeneProduct393885 (Entrez Gene)
zgc:92124GeneProduct447804 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1359"
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