CFTR activity in the plasma membrane (Rattus norvegicus)

Description

Mechanisms that regulate the Cl excretion by CFTR channel.

View approved pathways at the new wikipathways.org.

Guggino WB, Stanton BA; ''New insights into cystic fibrosis: molecular switches that regulate CFTR.''; Nat Rev Mol Cell Biol, 2006 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
126277	view	04:27, 20 April 2023	Egonw	License is CCZero
78473	view	10:27, 7 January 2015	MaintBot	added missing graphIds
69430	view	19:03, 8 July 2013	MaintBot	Updated to 2013 gpml schema
67107	view	10:07, 26 June 2013	Christine Chichester	Ontology Term : 'chloride ion transport pathway' added !
41754	view	02:40, 2 March 2011	MaintBot	Removed redundant pathway information and comments
36245	view	00:59, 12 March 2010	Khanspers	Modified categories
36154	view	15:08, 3 March 2010	Karin	Modified description
36153	view	15:06, 3 March 2010	Karin	New pathway

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Name	Type	Database reference
AMPK	GeneProduct	78975 (Entrez Gene)
CFTR	GeneProduct	24255 (Entrez Gene)
ERM BD	GeneProduct
Ezrin	GeneProduct	54319 (Entrez Gene)
NBD1	GeneProduct
NBD2	GeneProduct
NHERF1	Protein	59114 (Entrez Gene)
NHERF2	Protein	116501 (Entrez Gene)
PDZ1	Protein	65144 (Entrez Gene)
PDZ2	GeneProduct	65144 (Entrez Gene)
PKA	GeneProduct	25636 (Entrez Gene)
PKC	GeneProduct	24681 (Entrez Gene)
PLC b1	GeneProduct	24654 (Entrez Gene)
PLC b2	GeneProduct	85240 (Entrez Gene)
PLC b3	GeneProduct	29322 (Entrez Gene)
PLC zeta	GeneProduct	497197 (Entrez Gene)
PP2A	GeneProduct	24672 (Entrez Gene)
R	GeneProduct
RACK1	GeneProduct	83427 (Entrez Gene)
Rho GTPase	GeneProduct	689752 (Entrez Gene)
SNAP23	GeneProduct	64630 (Entrez Gene)
SYN1A	GeneProduct	24949 (Entrez Gene)
b2-AR	GeneProduct	24176 (Entrez Gene)
cAMP	GeneProduct

No annotated interactions