Transcription factors regulate miRNAs related to cardiac hypertrophy (Homo sapiens)

Description

Transcription Factors that possibly regulate the expression of microRNAs related to cardiac hypertrophy.

Interactions found by using TransMir. MicroRNAs are represented by a purple color and a rounded rectangle.

Proteins on this pathway have targeted assays available via the CPTAC Assay Portal.

View approved pathways at the new wikipathways.org.

No bibliography

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Revision	Action	Time	User	Comment
126397	view	15:30, 26 April 2023	Egonw	License is CCZero
117836	view	15:11, 22 May 2021	Eweitz	Modified title
116475	view	10:18, 7 May 2021	Eweitz	Modified title
105834	view	23:09, 15 August 2019	Khanspers	Modified description
103005	view	15:06, 31 January 2019	Marvin M2	Updated miRNA Ensembl IDs
98362	view	06:19, 24 August 2018	Egonw	Updated the MIR21 identifier.
97675	view	12:52, 1 June 2018	AMTan	Ontology Term : 'cardiac muscle cell' added !
84698	view	21:18, 15 March 2016	Khanspers	Quick edit to datanode annotation or property
68890	view	17:27, 8 July 2013	MaintBot	Updated to 2013 gpml schema
59091	view	22:10, 21 February 2013	MaintBot	Updated Ensembl and UniProt data source
45092	view	21:10, 6 October 2011	Khanspers	Ontology Term : 'DOID:114' removed !
45091	view	21:10, 6 October 2011	Khanspers	Ontology Term : 'hypertrophic cardimyopathy pathway' added !
45090	view	21:03, 6 October 2011	Khanspers	Ontology Term : 'heart disease' added !
41041	view	23:15, 1 March 2011	MaintBot	Removed redundant pathway information and comments
37871	view	17:27, 13 July 2010	Khanspers	Modified categories
37548	view	11:54, 10 June 2010	MLevels
37547	view	11:53, 10 June 2010	MLevels	Modified description
37546	view	11:52, 10 June 2010	MLevels
37545	view	11:46, 10 June 2010	MLevels	Modified description
37544	view	11:44, 10 June 2010	MLevels
37543	view	11:37, 10 June 2010	MLevels	Periodical save, work in progress
37542	view	11:27, 10 June 2010	MLevels	New pathway

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Name	Type	Database reference
AKT1	GeneProduct	207 (Entrez Gene)
AKT2	GeneProduct	208 (Entrez Gene)
Calcineurin	GeneProduct	5534 (Entrez Gene)
MEF-2	GeneProduct	50804 (Entrez Gene)
MIR1-2	Rna	ENSG00000284453 (Ensembl)
MIR29A	GeneProduct	ENSG00000284032 (Ensembl)
NFkB	GeneProduct	4790 (Entrez Gene)
RAS	GeneProduct	5923 (Entrez Gene)
STAT3	GeneProduct	6774 (Entrez Gene)
TGFbeta	GeneProduct	7040 (Entrez Gene)
hsa-mir-1-1	Rna	ENSG00000199017 (Ensembl)
hsa-mir-125b-1	Rna	ENSG00000207971 (Ensembl)
hsa-mir-125b-2	Rna	ENSG00000207863 (Ensembl)
hsa-mir-133b	Rna	ENSG00000199080 (Ensembl)
hsa-mir-21	Rna	ENSG00000284190 (Ensembl)

No annotated interactions