Small ligand GPCRs (Rattus norvegicus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Platelet ActivatingLysophosphatidic AcidPtafrGq/G11 PathwayGq/G11 PathwayGi PathwayMelatoninCannabinoidProstanoidsCnr1Cnr2S1pr1Lpar1S1pr3S1pr2S1pr4Mtnr1aMtnr1bMel-1CPTGDRPtger1Ptger2Ptger3Ptger4PtgfrPtgirTbxa2rName: Small ligand GPCRsLast Modified: 10/17/2013Organism: Rattus norvegicus


Description

G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: [Wikipedia](https://en.wikipedia.org/wiki/G_protein–coupled_receptor) These small ligand receptors are part of the Rhodopsin-like family of GPCRs. Source: [Wikipedia](https://en.wikipedia.org/wiki/Rhodopsin-like_receptors)

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP247(r21199) with a 89% conversion rate.

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Quality Tags

Image:NonTypical.pngAnnotated lists
Image:Curated.pngApproved version
Image:NeedsRef.pngAdd references
Image:Unconnected.pngFix interactions
Image:MissingXref.pngAnnotate nodes
Homology Converted

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
137232
Approved
view10:09, 1 March 2025EgonwModified description
117014view11:24, 16 May 2021EweitzModified title
96074view18:43, 15 February 2018KhanspersModified description
96073view18:43, 15 February 2018KhanspersModified description
71786view20:32, 17 October 2013MaintBotAutomated update of data sources
71301view16:58, 17 October 2013MaintBotAutomated update of data sources
71008view18:57, 22 September 2013EgonwConverted pathway Label nodes into PathWay DataNodes, and three Labels into Metabolite DataNodes.
69389view18:57, 8 July 2013MaintBotUpdated to 2013 gpml schema
67649view11:44, 26 June 2013DdiglesOntology Term : 'G protein mediated signaling pathway' added !
62847view05:04, 3 May 2013MaintBotUpdated UniProt data source
41704view02:37, 2 March 2011MaintBotRemoved redundant pathway information and comments
34085view19:14, 9 December 2009MaintBotAutomatic update of empty xrefs
32352view13:38, 15 August 2009MaintBotFixed text labels
31978view13:10, 14 August 2009MaintBotFixed group labels
31401view20:49, 13 August 2009MaintBotFixed text labels
30920view00:33, 30 July 2009MaintBotConverted from Homo sapiens
21019view11:30, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Small ligand GPCRs]] moved to [[Pathway:WP161]]: Moved to stable identifier
8394view13:46, 7 January 2008MaintBot[[Pathway:Rat:Small ligand GPCRs]] moved to [[Pathway:Rattus norvegicus:Small ligand GPCRs]]: Renaming species
7814view16:19, 18 December 2007MaintBotfixed category names
7448view12:42, 4 November 2007MaintBotAdded categories to GPML
19542view22:20, 22 May 2007M.Ramirezgpml file for [[Rat:Small_ligand_GPCRs]]
6594view22:20, 22 May 2007Nsalomonisgpml file for [[Rat:Small_ligand_GPCRs]]

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
CannabinoidMetaboliteCHEBI:67194 (ChEBI)
Cnr1GeneProduct25248 (Entrez Gene)
Cnr2GeneProduct57302 (Entrez Gene)
Gi PathwayPathway
Gq/G11 PathwayPathway
Lpar1GeneProduct116744 (Entrez Gene)
Mel-1CGeneProduct
MelatoninMetaboliteCHEBI:16796 (ChEBI)
Mtnr1aGeneProduct114211 (Entrez Gene)
Mtnr1bGeneProduct192646 (Entrez Gene)
PTGDRGeneProduct498475 (Entrez Gene)
ProstanoidsMetaboliteCHEBI:26347 (ChEBI)
PtafrGeneProduct58949 (Entrez Gene)
Ptger1GeneProduct25637 (Entrez Gene)
Ptger2GeneProduct81752 (Entrez Gene)
Ptger3GeneProduct24929 (Entrez Gene)
Ptger4GeneProduct84023 (Entrez Gene)
PtgfrGeneProduct25652 (Entrez Gene)
PtgirGeneProduct292661 (Entrez Gene)
S1pr1GeneProduct29733 (Entrez Gene)
S1pr2GeneProduct29415 (Entrez Gene)
S1pr3GeneProduct306792 (Entrez Gene)
S1pr4GeneProduct314649 (Entrez Gene)
Tbxa2rGeneProduct24816 (Entrez Gene)

Annotated Interactions

No annotated interactions
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