miRNAs and TFs in iPS Cell Generation (Mus musculus)

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1SpliceosomeBat1aPhf5aOct4Prpf4SnrpamiR-200b-3pSox2Sf3a3miR-429-3pmiR-200a-3pmiR-183-5p


Description

This pathway describes how a set of miRNA is responsible for different steps of induced pluripotent stem cell generation in a mouse embryonic fibroblasts cell model, infected with Oct3/4, Sox2, Klf4 and c-Myc.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Chen J, Wang G, Lu C, Guo X, Hong W, Kang J, Wang J; ''Synergetic cooperation of microRNAs with transcription factors in iPS cell generation.''; PLoS One, 2012 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
104965view13:33, 27 June 2019FehrhartModified description
89964view18:15, 6 October 2016Mkutmonfix unconnected lines and layout
87846view11:49, 25 July 2016ElisaOntology Term : 'regulatory pathway' added !
69065view18:08, 8 July 2013MaintBotUpdated to 2013 gpml schema
58155view22:21, 8 February 2013MaintBotModified categories
54266view14:12, 26 November 2012SusanStart
54265view13:50, 26 November 2012SusanPeriodical save, work in progress
54264view13:33, 26 November 2012SusanNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Bat1aGeneProduct53817 (Entrez Gene)
Oct4GeneProduct18999 (Entrez Gene)
Phf5aGeneProduct68479 (Entrez Gene)
Prpf4GeneProduct70052 (Entrez Gene)
Sf3a3GeneProduct75062 (Entrez Gene)
SnrpaGeneProduct53607 (Entrez Gene)
Sox2GeneProduct20674 (Entrez Gene)
miR-183-5pRnaMIMAT0000212 (miRBase Sequence)
miR-200a-3pRnaMIMAT0000657 (miRBase Sequence)
miR-200b-3pRnaMIMAT0000233 (miRBase Sequence)
miR-429-3pRnaMIMAT0001537 (miRBase Sequence)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2375"
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