Small ligand GPCRs (Homo sapiens)

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G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: [Wikipedia](https://en.wikipedia.org/wiki/G_protein–coupled_receptor) These small ligand receptors are part of the Rhodopsin-like family of GPCRs. Source: [Wikipedia](https://en.wikipedia.org/wiki/Rhodopsin-like_receptors)