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Graham EE, Walsh RJ, Hirst CM, Maggs JL, Martin S, Wild MJ, Wilson ID, Harding JR, Kenna JG, Peter RM, Williams DP, Park BK; ''Identification of the thiophene ring of methapyrilene as a novel bioactivation-dependent hepatic toxicophore.''; J Pharmacol Exp Ther, 2008 PubMedEurope PMCScholia
Ratra GS, Cottrell S, Powell CJ; ''Effects of induction and inhibition of cytochromes P450 on the hepatotoxicity of methapyrilene.''; Toxicol Sci, 1998 PubMedEurope PMCScholia
Craig A, Sidaway J, Holmes E, Orton T, Jackson D, Rowlinson R, Nickson J, Tonge R, Wilson I, Nicholson J; ''Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat.''; J Proteome Res, 2006 PubMedEurope PMCScholia
Uehara T, Kiyosawa N, Hirode M, Omura K, Shimizu T, Ono A, Mizukawa Y, Miyagishima T, Nagao T, Urushidani T; ''Gene expression profiling of methapyrilene-induced hepatotoxicity in rat.''; J Toxicol Sci, 2008 PubMedEurope PMCScholia
Mercer AE, Regan SL, Hirst CM, Graham EE, Antoine DJ, Benson CA, Williams DP, Foster J, Kenna JG, Park BK; ''Functional and toxicological consequences of metabolic bioactivation of methapyrilene via thiophene S-oxidation: Induction of cell defence, apoptosis and hepatic necrosis.''; Toxicol Appl Pharmacol, 2009 PubMedEurope PMCScholia
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