Methylcitrate cycle (Mycobacterium tuberculosis)

Description

The Methylcitrate cycle oxidizes Propionyl-CoA to pyruvate.

View approved pathways at the new wikipathways.org.

Muñoz-Elías EJ, Upton AM, Cherian J, McKinney JD; ''Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence.''; Mol Microbiol, 2006 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
87827	view	11:43, 25 July 2016	Elisa	Ontology Term : 'classic metabolic pathway' added !
78230	view	16:33, 14 December 2014	MaintBot	Added a missing data source.
78229	view	16:32, 14 December 2014	MaintBot	Widened boxes a bit to make all labels visable.
70838	view	16:58, 11 September 2013	Andra	Periodical save, work in progress
70818	view	17:06, 9 September 2013	Andra	Modified description
70817	view	17:03, 9 September 2013	Andra
70816	view	16:59, 9 September 2013	Andra	Specify description
70814	view	16:48, 9 September 2013	Andra	Finished pathways
70813	view	16:35, 9 September 2013	Andra	Periodical save, work in progress
70812	view	16:24, 9 September 2013	Andra	Periodical save, work in progress
70811	view	16:14, 9 September 2013	Andra	New pathway

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Name	Type	Database reference
2-methylcitrate dehydratase activity	GeneProduct	GO:0047547 (GeneOntology)
2-methylcitrate synthase activity	GeneProduct	GO:0050440 (GeneOntology)
2-methylisocitrate lyase	GeneProduct
Aconitase	GeneProduct
Fumarase	GeneProduct
Fumarate	Metabolite	4573886 (Chemspider)
Malate	Metabolite	140981 (Chemspider)
Methyl Isocitrate	Metabolite	1161 (Chemspider)
Methylcitrate	Metabolite	500 (Chemspider)
Oxaloacetate	Metabolite	2509917 (Chemspider)
Propionyl-CoA	Metabolite	83731 (Chemspider)
Pyruvate	Metabolite	96901 (Chemspider)
Succinate	Metabolite	140973 (Chemspider)
malate dehydrogenase activity	GeneProduct	GO:0016615 (GeneOntology)
malate quinone oxidoreductase;	GeneProduct
succinate dehydrogenase activity	GeneProduct	GO:0000104 (GeneOntology)

No annotated interactions