Glyoxylate cycle (Mycobacterium tuberculosis)

From WikiPathways

Jump to: navigation, search
21, 3, 4, 6, 7ICL2bOxaloacetateMQOSuccinateGlyoxylateMDHMLSMalateAcetyl-CoACitrateCITAIsocitrateICL1ACNICL2aFUMSDHAFumarateCITEAcetyl-CoA1, 4-6SDHBSDHCSDHDACN


Description

The glyoxylate cycle transforms acetyl-CoA derived from the β-oxidation of fatty acids into oxaloacetate, an intermediate of the citric acid cycle

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

View all...
  1. Bharadwaj VP, Katoch VM, Sharma VD, Kannan KB, Datta AK, Shivannavar CT; ''Metabolic studies on mycobacteria. IV. Assay of isocitrate lyase and malate synthase activity in M. leprae.''; Indian J Lepr, 1987 PubMed Europe PMC Scholia
  2. Muñoz-Elías EJ, Upton AM, Cherian J, McKinney JD; ''Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence.''; Mol Microbiol, 2006 PubMed Europe PMC Scholia
  3. Muñoz-Elías EJ, McKinney JD; ''Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence.''; Nat Med, 2005 PubMed Europe PMC Scholia
  4. Wheeler PR, Ratledge C; ''Use of carbon sources for lipid biosynthesis in Mycobacterium leprae: a comparison with other pathogenic mycobacteria.''; J Gen Microbiol, 1988 PubMed Europe PMC Scholia
  5. KORNBERG HL, KREBS HA; ''Synthesis of cell constituents from C2-units by a modified tricarboxylic acid cycle.''; Nature, 1957 PubMed Europe PMC Scholia
  6. Seshadri R, Murthy PS, Venkitasubramanian TA; ''Isociatrate lyase in mycobacteria.''; Indian J Biochem Biophys, 1976 PubMed Europe PMC Scholia
  7. McKinney JD, Höner zu Bentrup K, Muñoz-Elías EJ, Miczak A, Chen B, Chan WT, Swenson D, Sacchettini JC, Jacobs WR Jr, Russell DG; ''Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase.''; Nature, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
97588view08:24, 28 May 2018Fehrhartupdated outdated uniprot ID for MLS
89931view13:42, 6 October 2016MkutmonModified description
77539view19:52, 23 September 2014KhanspersOntology Term : 'glyoxylate and dicarboxylate metabolic pathway' added !
77538view19:47, 23 September 2014Khanspersconnected interactions
71840view19:46, 18 October 2013MaintBotUpdated UniProt/TrEMBL data source
70854view10:23, 12 September 2013AndraSpecify description
70849view08:59, 12 September 2013Mkutmoncircular structure
70841view17:29, 11 September 2013AndraModified description
70840view17:09, 11 September 2013AndraAdded MLS and ICL references
70839view17:06, 11 September 2013AndraPeriodical save, work in progress
70836view22:41, 10 September 2013AndraSpecify description
70834view17:24, 10 September 2013AndraMade it more circular
70831view16:30, 10 September 2013Andrafirst draft
70830view16:28, 10 September 2013AndraPeriodical save, work in progress
70829view16:18, 10 September 2013AndraPeriodical save, work in progress
70828view16:08, 10 September 2013AndraPeriodical save, work in progress
70827view15:57, 10 September 2013AndraPeriodical save, work in progress
70826view15:25, 10 September 2013Andrawork in progress
70825view15:14, 10 September 2013AndraPeriodical save, work in progress
70821view12:49, 10 September 2013AndraAdded source reference
70820view12:48, 10 September 2013AndraFirst Draft
70819view12:47, 10 September 2013AndraNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACNGeneProductL7N4I7 (Uniprot-TrEMBL)
Acetyl-CoAMetabolite392413 (Chemspider)
CITAGeneProductP63777 (Uniprot-TrEMBL)
CITEGeneProductO06162 (Uniprot-TrEMBL)
CitrateMetabolite29081 (Chemspider)
FUMGeneProductO53446 (Uniprot-TrEMBL)
FumarateMetabolite4573886 (Chemspider)
GlyoxylateMetabolite2849615 (Chemspider)
ICL1GeneProductP0A5H3 (Uniprot-TrEMBL)
ICL2aGeneProductL0T829 (Uniprot-TrEMBL)
ICL2bGeneProductL0T891 (Uniprot-TrEMBL)
IsocitrateMetabolite4573809 (Chemspider)
MDHGeneProductP0A5J6 (Uniprot-TrEMBL)
MLSGeneProductP9WK16 (Uniprot-TrEMBL)
MQOGeneProductP65419 (Uniprot-TrEMBL)
MalateMetabolite140981 (Chemspider)
OxaloacetateMetabolite2509917 (Chemspider)
SDHAGeneProductL7N501 (Uniprot-TrEMBL)
SDHBGeneProductL7N605 (Uniprot-TrEMBL)
SDHCGeneProductL7N510 (Uniprot-TrEMBL)
SDHDGeneProductL0TC66 (Uniprot-TrEMBL)
SuccinateMetabolite140973 (Chemspider)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2566"
Personal tools