TGF-beta receptor signaling pathway (Mus musculus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Proteolytic cleavageReaction through unknown mechanisms/moleculesECDephosphorylationNucleusCYMolecular associationCYReceptorUbiquitinationDeacetylationEnzyme complexAutophosphorylationNUCYCYNU -> CYMTNUENNUNUNUCYCYCYDGlycosylationGolgi apparatusNUAcetylationCYCYNUNUNUCYNUNUActivationNUProteins in a complex interactionSumoylationNUNUGOEndoplasmic reticulumCYEndosomeNUERDesumoylationNUAccession Number: NetPath 7; cellmap:7MethylationTranslocationNUCYCYCYDeubiquitinationNUCYCYCYNU(Protein-protein interaction)ExtracellularMolecule in the pathwayNUMitochondriaNUPalmitoylationNUNUControlCytoplasmPlasma membraneCYCYRecruitmentPhosphorylationLigandNUPMNUInhibitionCYNUCYNUCYGlycosylationCYDemethylationCYCYCYNU -> CYCYBtrcTgfbr2CtcfTgfbr2E2f5Atf3PcafJunbMef2cUbe2d1Camk2dZfhx1aRock1JunRbl2NfycMllt7Zfhx1bAp2b1EngSmad3Tgfbr3Skp1aNup153Cdc27Cdc27Cdk4Cdc27E2f4Runx2Ctnnb1Rb1Cdkn1aTgfbr1Prkar2aSNW1Mapk14Foxg1Anapc4NfybFoxh1Smad7Arrb2Smurf2Cdc16E2f5Rbx1Dcp1aTgfbr1Smad2Lef1Map2k6E2f4Tfdp1Tgfb1BtrcAnapc10Trp73Yap1Smad3MycCcnd1Cul1Smad3VdrSp1Anapc5Smad2Zfyve9Snx4SkilAnapc7Tgfbr2Cav1Tgfb3Xpo1Fkbp1aPIK3R1Cul1FntaGene SymbolSmad4Smurf1Tgfbr2E2f5Smad2Tgfbr1Cd44Pik3r2Tgfbr3Anapc2Smad2Tgfb1Cdc16Cops5Cri2Smad3Tgfbr2Cdc2aPias2DaxxAtf2Anapc2Rbx1Ets1TgifRbx1CrebbpStk11ipE2f5FosSnip1Tgfbr2Tgfb2Tgfb2Smad4Anapc4ArSnx6Stk11Tgfbr2Tgfbr3FosbRb1Nup214PrkcdMapk8Rbl1Dvl1Tgfb3Cul1Fzr1Skp1aE2f4Tgfbr3Hoxa9E2f4Smad4Jund1Smad3Tgfbr3Prkcb1Smad6Mapk14Map3k7ip1Cdc23Tgfbr2SkiE2f5Map2k3Tfdp1Rbl1Ep300Ube2d3Smurf2Tgfb1Tfdp2Axin1Dcp1aStrapHspa8Stambpl1Pard3Kpnb1Dab2Kpnb1Tfdp2Sumo1E2f5HgsCcnb2Esr1Mef2aSmad3Cdc25aTgfb2Rbl1Ube2d2Rbl1Eif3s2E2f4Anapc5Axin2Smad4Tgfbr2Prkar1bSdc2Cdk6Anapc1Tfdp2Pias1Snx2Rock1Ccne1Tgfb3Rb1Map3k7Snx6Foxo3aAcvrl1Snx1NfyaE2f4Rbl2Tgfb3Anapc10Smad7Ncoa1Gipc1Smad3StrapTrap1Smad4Esr1Foxo1Erbb2ipAnapc7CDK2Rbl1Ppp2r2aHdac1Anapc1Camk2bSmad4Camk2aCamk2gTgfb1Tgfbr1Tfdp1Trp53Smad3PRKCGSmad3Hnf4aSmad7Cdc23SparcTgfbr3Mapk8Smurf1Cited1Tgfbr2Name: TGF-beta receptor signaling pathwayOrganism: Mus musculus


Description

No description

Comments

GenMAPP notes 
NetPath 7; cellmap:7 - TGF-beta Receptor Signaling Pathway

The TGF-beta Receptor Signaling pathway was kindly reviewed by Van Le Hong, Wei He and other members of Joan Massague’s lab. This cancer signaling pathway is available at Cancer Cell Map (http://cancer.cellmap.org) and NetPath (http://www.netpath.org) and is part of a collaborative project between the Computational Biology Center at Memorial Sloan-Kettering Cancer Center (http://cbio.mskcc.org), PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the Cancer Cell Map and NetPath websites until the pathway is published.

GenMAPP remarks 
http://cancer.cellmap.org; http://www.netpath.org

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Quality Tags

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Ontology Terms

Pathway Ontology : androgen signaling pathway
 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
118015view11:34, 23 May 2021EweitzModified title
111024view14:42, 30 June 2020L DupuisConverted interactions in legend to graphical lines
73847view00:33, 26 February 2014MaintBotupdated schema
71764view20:29, 17 October 2013MaintBotremoved data source from nodes without identifier
67695view11:50, 26 June 2013DdiglesOntology Term : 'transforming growth factor-beta superfamily mediated signaling pathway' added !
41259view00:20, 2 March 2011MaintBotRemoved redundant pathway information and comments
34374view22:44, 9 December 2009MaintBotAutomatic update of empty xrefs
28139view21:51, 27 January 2009KhanspersReverted to version '11:31, 14 November 2008' by Khanspers
28138view21:50, 27 January 2009KhanspersChanged name
21221view11:31, 14 November 2008MaintBot[[Pathway:Mus musculus:TGF-beta-Receptor NetPath 7]] moved to [[Pathway:WP258]]: Moved to stable identifier
8436view13:46, 7 January 2008MaintBot[[Pathway:Mouse:TGF-beta-Receptor NetPath 7]] moved to [[Pathway:Mus musculus:TGF-beta-Receptor NetPath 7]]: Renaming species
7834view16:21, 18 December 2007MaintBotfixed category names
7305view12:42, 4 November 2007MaintBotAdded categories to GPML
6501view22:19, 22 May 2007A.PandeyReverted to version '14:05, 9 March 2007' by Thomas

External references

DataNodes

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Annotated Interactions

No annotated interactions
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