Limb and fin development (Mus musculus)

From WikiPathways

Jump to: navigation, search
13Regulatory ElementsEtv genesSall genesEpha genesWnt genesTelomeric Gene DesertPitx genesFgf genesBmp genesHox genesTbx genesosr genesAnd genesHand genesfgf17hoxa13pdlim7ptc1/ptch1wnt2bTbx5osr1fibinhoxa11hand1fgf10Pitx2fgf4etv5/etv5awnt8cfgf24wnt3aGrem1bmp2apea3Pitx1raldh2osr2hoxc10Tbx4retinoic acidTbx3bmp2betv4fgf9Meis1hand2chordinNogginhoxd13a/ hoxd13and1shh/shhaermfgf8a/ fgf8gli3and2Epha4Epha3Sall1Sall3Island 2Island 4CsBCscCNS 65CNS 39Hoxd10Hoxd11Hoxd12


Description

No description

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

View all...
  1. Mao J, McGlinn E, Huang P, Tabin CJ, McMahon AP; ''Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb.''; Dev Cell, 2009 PubMed Europe PMC Scholia
  2. Agarwal P, Wylie JN, Galceran J, Arkhitko O, Li C, Deng C, Grosschedl R, Bruneau BG; ''Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo.''; Development, 2003 PubMed Europe PMC Scholia
  3. Riddle RD, Johnson RL, Laufer E, Tabin C; ''Sonic hedgehog mediates the polarizing activity of the ZPA.''; Cell, 1993 PubMed Europe PMC Scholia
  4. Bouldin CM, Gritli-Linde A, Ahn S, Harfe BD; ''Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterning.''; Proc Natl Acad Sci U S A, 2010 PubMed Europe PMC Scholia
  5. Schulte CJ, Allen C, England SJ, Juárez-Morales JL, Lewis KE; ''Evx1 is required for joint formation in zebrafish fin dermoskeleton.''; Dev Dyn, 2011 PubMed Europe PMC Scholia
  6. Nohno T, Noji S, Koyama E, Ohyama K, Myokai F, Kuroiwa A, Saito T, Taniguchi S; ''Involvement of the Chox-4 chicken homeobox genes in determination of anteroposterior axial polarity during limb development.''; Cell, 1991 PubMed Europe PMC Scholia
  7. Izpisúa-Belmonte JC, Tickle C, Dollé P, Wolpert L, Duboule D; ''Expression of the homeobox Hox-4 genes and the specification of position in chick wing development.''; Nature, 1991 PubMed Europe PMC Scholia
  8. Galli A, Robay D, Osterwalder M, Bao X, Bénazet JD, Tariq M, Paro R, Mackem S, Zeller R; ''Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development.''; PLoS Genet, 2010 PubMed Europe PMC Scholia
  9. Duboc V, Logan MP; ''Regulation of limb bud initiation and limb-type morphology.''; Dev Dyn, 2011 PubMed Europe PMC Scholia
  10. Tarchini B, Duboule D, Kmita M; ''Regulatory constraints in the evolution of the tetrapod limb anterior-posterior polarity.''; Nature, 2006 PubMed Europe PMC Scholia
  11. Sims K Jr, Eble DM, Iovine MK; ''Connexin43 regulates joint location in zebrafish fins.''; Dev Biol, 2009 PubMed Europe PMC Scholia
  12. King M, Arnold JS, Shanske A, Morrow BE; ''T-genes and limb bud development.''; Am J Med Genet A, 2006 PubMed Europe PMC Scholia
  13. Tanaka M; ''Molecular and evolutionary basis of limb field specification and limb initiation.''; Dev Growth Differ, 2013 PubMed Europe PMC Scholia
  14. Sheth R, Grégoire D, Dumouchel A, Scotti M, Pham JM, Nemec S, Bastida MF, Ros MA, Kmita M; ''Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth.''; Development, 2013 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118206view11:43, 26 May 2021EweitzModified title
97686view15:08, 1 June 2018Fehrhartcorrected ID
97589view08:28, 28 May 2018Fehrhartadded ID
88675view15:40, 12 August 2016JmeliusOntology Term : 'regulatory pathway' added !
85552view07:45, 29 May 2016EgonwReplaced a mim-conversion with Arrow.
79792view16:03, 16 April 2015Mkutmonfixed unconnected line
78418view10:26, 7 January 2015MaintBotadded missing graphIds
73066view19:03, 22 December 2013LmjacksonModified title
73065view19:01, 22 December 2013LmjacksonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CNS 39GeneProductConserved Noncoding Sequence
CNS 65GeneProductConserved Noncoding Sequence
CsBGeneProduct
CscGeneProduct
Epha3GeneProductMGI:99612 (MGI)
Epha4GeneProductMGI:98277 (MGI)
Grem1GeneProduct
Hoxd10GeneProductMGI:96202 (MGI)
Hoxd11GeneProductMGI:96203 (MGI)
Hoxd12GeneProductMGI:96204 (MGI)
Island 2GeneProduct
Island 4GeneProduct
Meis1GeneProduct
NogginGeneProduct
Pitx1GeneProduct
Pitx2GeneProduct
Sall1GeneProductMGI:1889585 (MGI)
Sall3GeneProductMGI:109295 (MGI)
Tbx3GeneProduct
Tbx4GeneProduct
Tbx5GeneProduct
and1GeneProductZDB-GENE-030131-9105 (ZFIN)
and2GeneProductZDB-GENE-041105-2 (ZFIN)
bmp2aGeneProduct
bmp2bGeneProduct
chordinGeneProduct
ermGeneProduct
etv4GeneProduct
etv5/etv5aGeneProductZDB-GENE-030131-9572 (ZFIN)
fgf10GeneProduct
fgf17GeneProduct
fgf24GeneProduct
fgf4GeneProduct
fgf8a/ fgf8GeneProductZDB-GENE-990415-72 (ZFIN)
fgf9GeneProduct
fibinGeneProduct
gli3GeneProductZDB-GENE-041111-162 (ZFIN)
hand1GeneProduct
hand2GeneProductZDB-GENE-000511-1 (ZFIN)
hoxa11GeneProductENSMUSG00000038210 (Ensembl)
hoxa13GeneProduct
hoxc10GeneProduct
hoxd13a/ hoxd13GeneProductZDB-GENE-990415-119 (ZFIN)
osr1GeneProduct
osr2GeneProduct
pdlim7GeneProduct
pea3GeneProduct
ptc1/ptch1GeneProduct
raldh2GeneProductZebrafish mutants for retinaldehyde dehydrogenase 2 (raldh2) lack pectoral fin buds
retinoic acid
shh/shhaGeneProductZDB-GENE-980526-166 (ZFIN)
wnt2bGeneProduct
wnt3aGeneProduct
wnt8cGeneProduct

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2604"
Personal tools