Triglyceride biosynthesis (Saccharomyces cerevisiae)

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Description

Triacylglycerol (TAG) is the major lipid reserve in plants and animals. The assembly of TAG occurs in the endoplasmic reticulum (ER). Four consecutive reactions are catalyzed by ER membrane bound enzymes. The two intermediates, phosphatidate and 1,2-diacylglycerol, are also substrates for the synthesis of membrane lipids glycosylglycerides and phosphoglycerides. Thus, the last step in the pathway, catalyzed by diacylglycerol acyltransferase, is the only dedicated step in triacylglycerol synthesis. Source: https://pathway.yeastgenome.org/.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Czabany T, Athenstaedt K, Daum G; ''Synthesis, storage and degradation of neutral lipids in yeast.''; Biochim Biophys Acta, 2007 PubMed Europe PMC Scholia
  2. ''diacylglycerol and triacylglycerol biosynthesis''; Yeast Pathways,

History

View all...
CompareRevisionActionTimeUserComment
135515view23:24, 20 September 2024KhanspersOntology Term : 'classic metabolic pathway' added !
135514view23:23, 20 September 2024Khanspersremoved GenMAPP comments
135513view23:21, 20 September 2024KhanspersModified description
135512view23:20, 20 September 2024Khanspersupdated reference
135511view23:09, 20 September 2024Khanspersoverhaul
124926view22:56, 31 December 2022EgonwFixed the AcylCoA identifier
117353view11:54, 20 May 2021EweitzModified title
69843view15:47, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
69616view20:34, 8 July 2013MaintBotUpdated to 2013 gpml schema
67721view11:54, 26 June 2013DdiglesOntology Term : 'triacylglycerol biosynthetic pathway' added !
41850view04:51, 2 March 2011MaintBotRemoved redundant pathway information and comments
36649view22:38, 9 April 2010MaintBotDescription and bibliography added from SGD
21239view11:31, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Triglyceride Biosynthesis]] moved to [[Pathway:WP266]]: Moved to stable identifier
12879view08:06, 17 May 2008MaintBotautomated metabolite conversion
8978view14:13, 7 January 2008MaintBotAdded to category $category
8976view14:13, 7 January 2008M.BraymerUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1,2-diacyl-sn-glycerol 3-phosphateMetabolite29089 (ChEBI)
1,2-diacyl-sn-glycerolMetabolite17815 (ChEBI)
1-acyl-sn-glycero-3-phosphocholineMetabolite17504 (ChEBI)
1-acyl-sn-glycerol 3-phosphateMetabolite16975 (ChEBI)
Acyl-CoAMetaboliteCHEBI:17984 (ChEBI)
COENZYME AMetaboliteCHEBI:15346 (ChEBI)
DGA1GeneProductYOR245C (Ensembl)
DPP1GeneProductYDR284C (Ensembl)
GPT2GeneProductYKR067W (Ensembl)
H2OMetabolite15377 (ChEBI)
LPP1GeneProductYDR503C (Ensembl)
LRO1GeneProductYNR008W (Ensembl)
PAH1GeneProductYMR165C (Ensembl)
PhosphateMetabolite43474 (ChEBI)
SCT1GeneProductYBL011W (Ensembl)
SLC1GeneProductS000002210 (SGD)
phosphatidylcholineMetabolite16110 (ChEBI)
sn-glycerol 3-phosphateMetabolite57597 (ChEBI)
triacyl-sn-glycerolMetabolite64615 (ChEBI)

Annotated Interactions

No annotated interactions

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