Proteasome degradation (Drosophila melanogaster)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none ATPAMP Ubiquitin/E1 ComplexUbiquitin/E2 ComplexE3/ProteinProteins to be DegradedUbiquitin/ProteinProteasome 26 S(PA700) (ATP dependent)p45 ATPase SubunitUnfolds and DegradesIntact ProteinsProteasome 20SCatalytic Core (p45)Activators ofDegrades only PeptidesPresentation by MHC class 1Oxidatively DamagedCytosolic Proteins20S ComplexLid subunitsAlpha subunitsBeta subunitsH2AFXH2AFZUba1UBE1LUBE2BUBE2D1UBE2D2effPros26.4NEDD4Rpt4Rpn2Rpn1Dox-A2Pros54Pros45Rpt1Tbp-1Rpt3Pros35Pros25Pros26Prosalpha7Pros29Prosbeta3l(2)05070Prosbeta2Prosbeta5CG12000PSME1PSME2IFNGPSMB9PSMB10PSMB8REGMov34Rpn7Rpn12CG9588PSMD10Rpn6Rpn5Rpn9Pros45PSMA6PSMA7ProsMA5CG17331HLA-AHLA-BHLA-CHLA-EHLA-FHLA-GCG6370CG33303Ubi-p63ECG12096HLA-HHLA-JHIST1H2ABName: Proteasome degradationOrganism: Drosophila melanogaster


Description

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Quality Tags

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Image:Curated.pngApproved version
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Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
116929
Approved
view09:46, 16 May 2021EweitzModified title
79434view02:57, 22 March 2015Khanspersupdate schema
79433view02:56, 22 March 2015KhanspersReverted to version '11:33, 26 June 2013' by Khanspers
77443view20:28, 8 September 2014MaintBotremoved old homology label
71516view19:22, 17 October 2013MaintBotAutomated update of data sources
68725view21:59, 6 July 2013MaintBotUpdated to 2013 gpml schema
67612view11:33, 26 June 2013DdiglesOntology Term : 'ubiquitin/proteasome degradation pathway' added !
40900view22:35, 1 March 2011MaintBotRemoved redundant pathway information and comments
21271view11:31, 14 November 2008MaintBot[[Pathway:Drosophila melanogaster:Proteasome Degradation]] moved to [[Pathway:WP281]]: Moved to stable identifier
9026view14:15, 7 January 2008MaintBotAdded to category $category
9024view14:14, 7 January 2008NsalomonisUploaded new pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
CG12000GeneProduct40639 (Entrez Gene)
CG12096GeneProduct32269 (Entrez Gene)
CG17331GeneProduct34999 (Entrez Gene)
CG33303GeneProduct2768916 (Entrez Gene)
CG6370GeneProduct37029 (Entrez Gene)
CG9588GeneProduct41672 (Entrez Gene)
Dox-A2GeneProduct35176 (Entrez Gene)
H2AFXGeneProduct (Entrez Gene)
H2AFZGeneProduct (Entrez Gene)
HIST1H2ABGeneProduct (Entrez Gene)
HLA-AGeneProduct (Entrez Gene)
HLA-BGeneProduct (Entrez Gene)
HLA-CGeneProduct (Entrez Gene)
HLA-EGeneProduct (Entrez Gene)
HLA-FGeneProduct (Entrez Gene)
HLA-GGeneProduct (Entrez Gene)
HLA-HGeneProduct (Entrez Gene)
HLA-JGeneProduct (Entrez Gene)
IFNGGeneProduct (Entrez Gene)
Mov34GeneProduct37894 (Entrez Gene)
NEDD4GeneProduct (Entrez Gene)
PSMA6GeneProduct (Entrez Gene)
PSMA7GeneProduct (Entrez Gene)
PSMB10GeneProduct (Entrez Gene)
PSMB8GeneProduct (Entrez Gene)
PSMB9GeneProduct (Entrez Gene)
PSMD10GeneProduct (Entrez Gene)
PSME1GeneProduct (Entrez Gene)
PSME2GeneProduct (Entrez Gene)
Pros25GeneProduct41531 (Entrez Gene)
Pros26.4GeneProduct42828 (Entrez Gene)
Pros26GeneProduct39855 (Entrez Gene)
Pros29GeneProduct37378 (Entrez Gene)
Pros35GeneProduct34359 (Entrez Gene)
Pros45GeneProduct33105 (Entrez Gene) PRS6_HUMAN
Pros54GeneProduct40388 (Entrez Gene)
ProsMA5GeneProduct36951 (Entrez Gene)
Prosalpha7GeneProduct36018 (Entrez Gene)
Prosbeta2GeneProduct39628 (Entrez Gene)
Prosbeta3GeneProduct41079 (Entrez Gene)
Prosbeta5GeneProduct45269 (Entrez Gene)
REGGeneProduct32274 (Entrez Gene)
Rpn12GeneProduct39845 (Entrez Gene)
Rpn1GeneProduct40174 (Entrez Gene)
Rpn2GeneProduct43449 (Entrez Gene)
Rpn5GeneProduct40717 (Entrez Gene)
Rpn6GeneProduct36638 (Entrez Gene)
Rpn7GeneProduct42641 (Entrez Gene)
Rpn9GeneProduct42802 (Entrez Gene)
Rpt1GeneProduct35701 (Entrez Gene)
Rpt3GeneProduct32047 (Entrez Gene) PRS6_HUMAN
Rpt4GeneProduct31567 (Entrez Gene)
Tbp-1GeneProduct42805 (Entrez Gene)
UBE1LGeneProduct (Entrez Gene)
UBE2BGeneProduct (Entrez Gene)
UBE2D1GeneProduct (Entrez Gene)
UBE2D2GeneProduct (Entrez Gene)
Uba1GeneProduct35998 (Entrez Gene)
Ubi-p63EGeneProduct38456 (Entrez Gene)
effGeneProduct41785 (Entrez Gene)
l(2)05070GeneProduct46058 (Entrez Gene) U13393

Annotated Interactions

No annotated interactions

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