Dopaminergic neurogenesis (Homo sapiens)

Description

Converted to human from mouse: [WP:WP1498](http://www.wikipathways.org/index.php/Pathway:WP1498). Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2855).

View approved pathways at the new wikipathways.org.

Pathway Ontology : nuclear factor, erythroid derived 2, like 2 signaling pathway

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Revision	Action	Time	User	Comment
137824	view	06:47, 8 March 2025	Egonw	Modified description
126378	view	17:55, 25 April 2023	Egonw	License is CCZero
117704	view	12:25, 22 May 2021	Eweitz	Modified title
106728	view	13:21, 17 September 2019	MaintBot	HMDB identifier normalization
106390	view	21:26, 28 August 2019	Khanspers	Modified description
105572	view	06:27, 9 August 2019	Khanspers	Modified description
87239	view	09:52, 20 July 2016	Susan	Ontology Term : 'dopamine signaling pathway' added !
79211	view	19:21, 12 March 2015	Khanspers	Modified title
79210	view	19:20, 12 March 2015	Khanspers	connected interaction
79204	view	18:05, 10 March 2015	Nsalomonis	Modified description
79203	view	18:05, 10 March 2015	Nsalomonis	Modified description
77959	view	21:51, 31 October 2014	Egonw	Modified description
77682	view	19:11, 7 October 2014	Nsalomonis	New pathway

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Name	Type	Database reference
ALDH1A1	GeneProduct	ENSG00000165092 (Ensembl)
ASCL1	GeneProduct	ENSG00000139352 (Ensembl)
CDKN1C	GeneProduct	ENSG00000129757 (Ensembl)
DDC	GeneProduct	ENSG00000132437 (Ensembl)
EN1	GeneProduct	ENSG00000163064 (Ensembl)
EN2	GeneProduct	ENSG00000164778 (Ensembl)
FGF8	GeneProduct	ENSG00000107831 (Ensembl)
FOXA2	GeneProduct	ENSG00000125798 (Ensembl)
GBX2	GeneProduct	ENSG00000168505 (Ensembl)
GLI1	GeneProduct	ENSG00000111087 (Ensembl)
GLI2	GeneProduct	ENSG00000074047 (Ensembl)
LMX1A	GeneProduct	ENSG00000162761 (Ensembl)
LMX1B	GeneProduct	ENSG00000136944 (Ensembl)
MSX1	GeneProduct	ENSG00000163132 (Ensembl)
NEUROD1	GeneProduct	ENSG00000162992 (Ensembl)
NEUROG2	GeneProduct	ENSG00000178403 (Ensembl)
NKX2-2	GeneProduct	ENSG00000125820 (Ensembl)
NKX6-1	GeneProduct	ENSG00000163623 (Ensembl)
NR4A2	GeneProduct	ENSG00000153234 (Ensembl)
OTX2	GeneProduct	ENSG00000165588 (Ensembl)
PITX3	GeneProduct	ENSG00000107859 (Ensembl)
RET	GeneProduct	ENSG00000165731 (Ensembl)
Retinoic acid	Metabolite	HMDB0001852 (HMDB)
SHH	GeneProduct	ENSG00000164690 (Ensembl)
SLC18A2	GeneProduct	ENSG00000165646 (Ensembl)
SLC6A3	GeneProduct	ENSG00000142319 (Ensembl)
SOX2	GeneProduct	ENSG00000181449 (Ensembl)
STAT3	GeneProduct	ENSG00000168610 (Ensembl)
TGFB1	GeneProduct	ENSG00000105329 (Ensembl)
TH	GeneProduct	ENSG00000180176 (Ensembl)
WNT1	GeneProduct	ENSG00000125084 (Ensembl)